Nu Zhang, Ph.D.

Associate Professor

Department of Microbiology, Immunology & Molecular Genetics

Currently seeking Ph.D. students

Dr. Zhang studies the mechanisms underlying the differentiation and retention of tissue resident memory T cells controlled by transforming growth factor-beta (TGF-B) signaling. In addition, we study the biology of CD8+ T cells under various settings, including autoimmunity, chronic infection and tumor immunity.

Professional Background
Education
- 2005 - Ph.D. - Immunology - Duke University
- 2000 - B.S. - Biochemistry and Molecular Biology - Peking University, China
Highlights

Rising Research Superstars Award from Long School of Medicine, UTHSCSA, 2019

Faculty of the Year: Annual Award from Department of MIMG, UTHSCSA, 2017

Voelcker Young Investigator Award, 2015

University of Texas System Rising STARs Award, 2014
Publications

Shruti Mishra, Wei Liao, Yong Liu, Ming Yang, Chaoyu Ma, Haijing Wu, Ming Zhao, Xin Zhang, Yuanzheng Qiu, Qianjin Lu and Nu Zhang. TGF-ß and Eomes control the homeostasis of CD8+ regulatory T cells. J. Exp. Med. 2021 Jan 4;218(1):e20200030. doi: 10.1084/jem.20200030.

https://doi.org/10.1084/jem.20200030

Yong Liu, Chaoyu Ma and Nu Zhang. Tissue-specific control of tissue resident memory T cells. Crit. Rev. Immunol. 2018 DOI:10.1615/CritRevImmunol. 2018025653

Chaoyu Ma, Shruti Mishra, Erika L. Demel, Yong Liu and Nu Zhang. TGF-ß controls the formation of kidney-resident T cells via promoting effector T cell extravasation. J. Immunol. 2017 Jan 15;198(2):749-756. doi: 10.4049/jimmunol.1601500.

Chaoyu Ma and Nu Zhang. Transforming growth factor-ß signaling is constantly shaping memory T cell population.Proc. Natl. Acad. Sci. U.S.A. 2015;Sep 1;112 (35): 11013-7. doi: 10.1073/ pnas. 1510119112.

Nu Zhang and Michael J. Bevan. Transforming growth factor-ß signaling controls the formation and maintenance of gut-resident memory T cells by regulating migration and retention. Immunity,2013 Oct 17;39 (4):687-96. doi: 10.1016/j.immuni.2013.08.019.

Nu Zhang and Michael J. Bevan. TGF-ß signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation. Nat Immunol. 2012 May 27; 13(7): 667-73. doi: 10.1038/ni.2319.

Nu Zhang and Michael J. Bevan. CD8+ T cells: foot soldiers of the immune system. Immunity. 2011 Aug; 35 (2): 161-168.

Nu Zhang, Ph.D.

Education

Highlights