Tim Hui-Ming Huang, Ph.D.
Professor and Chair - Department of Molecular Medicine
Alice P. McDermott President’s Distinguished University Chair in Molecular Medicine
Max and Minnie Tomerlin Voelcker Distinguished University Chair in Targeted Cancer Therapy
Currently seeking M.S. & Ph.D. students
Dr. Tim Huang's lab has been conducting epigenetic/genetic analyses of cancer for the last twenty-nine years and has pioneered the development of high-throughput microarray and next-generation sequencing technologies for integrative analysis of cancer genomes. These omics approaches are used in combination with statistical and bioinformatic tools to develop biological models of tumor progression.
More recently, our research team has developed novel technologies to characterize single cancer cells and to address intra-tumor heterogeneity in prostate cancer patients. These novel technologies include isolation of single prostate tumor cells from blood and urine samples, single-cell expression profiling with microfluidic devices, and single-cell topographical analysis using atomic force microscopy.
The novel technologies will now be used for early detection and for identifying prostate cancer patients who are at risk of advanced development.
Related Diseases: Breast, prostate, lung and endometrial cancers.
Techniques: Single-cell genomics and omics.