Journal Article
Curiel TJ. Age effects of distinct immune checkpoint blockade treatments in a mouse melanoma model Experimental Gerontology 2018 Jan;105:146-154.
Ellen Kraig, Leslie A. Linehan, Hanyu Liang, Terry Q. Romo,
Qianqian Liu, Yubo Wu, Adriana D. Benavides, Tyler J. Curiel,
Martin A. Javors, Nicolas Musi, Laura Chiodo, Wouter Koek,
Jonathan A.L. Gelfond, Dean L. Kellogg. A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: Immunological, physical performance, and cognitive effects Experimental Gerontology 2018 Jan;105:53-69.
Zhang X., Huai-Chin Chiang, Yao Wang, Chi Zhang, Sabrina Smith, Xiayan Zhao, Sreejith Nair, Joel Michalek, Ismail Jatoi, Meeghan Lautner, Boyce Oliver, Howard Wang, Anna Petit, M Teresa Soler Monso, Joan Brunet, Francesca Mateo, Miguel Pujana, Elizabeth Poggi, Krysta Chaldekas, Claudine Isaacs, Beth Peshkin, Oscar Ochoa, Frederic Che'din, Constantine Theoharis, Lu-Zhe Sun, Tyler Curiel, Richard Elledge, Victor Jin, Yanfen Hu, and Rong Li. Attenuation of RNA Polymerase II Pausing Mitigates BRCA1-Associated R-loop Accumulation and Tumorigenesis Nat Commun 2017 Jun;26(8).
Curiel TJ. Tumor cell-intrinsic PD-L1: a novel metabolic balancing act with clinical potential Autophagy 2017 Jan;13(5):987-988.
Curiel TJ. Follicle-stimulating hormone receptor is expressed by most ovarian cancer subtypes and is a safe and effective immunotherapeutic target Clinical Cancer Research 2017 Jan;23:441-453.
Curiel TJ. Considerations for successful cancer immunotherapy in aged hosts Clinical & Experimental Immunology 2017 Jan;187:53-63.
Curiel TJ. Biphasic rapamycin effects in lymphoma and carcinoma treatment Cancer Research 2017 Jan;77:520-531.
Curiel TJ. Acquired resistance to BRAF inhibitors restores immunosuppressive myeloid cells that impair immunotherapy against autochthonous mouse melanoma Cancer Research 2017 Jan;77:1599-1610.
Curiel TJ. Characterization of tumor-driven Th17-to-Treg cell transdifferentiation Nature Communications 2017 Jan;8.
Curiel TJ. Tumor-extrinsic discoidin domain receptor 1 promotes mammary tumor growth by regulating adipose stromal interleukin 6 production in mice Journal of Biological Chemistry 2017 Jan;293(8):2841-2849.
Curiel TJ. Tumor cell-independent estrogen signaling drives progression through mobilization of myeloid-derived suppressor cells Cancer Discovery 2017 Jan;7:72-85.
Curiel TJ. Tumor intrinsic PD-L1 promotes tumor initiating cell generation and functions Signal Transduction and Targeted Therapy 2016 Jan;.
Curiel TJ. Tumor-intrinsic PD-L1 signals regulate cell growth, pathogenesis and autophagy in ovarian cancer and melanoma Cancer Research 2016 Jan;76:6964-6974.
Curiel TJ. Immune stimulatory effects of rapamycin are mediated by stimulation of antitumor γδ T cells Cancer Research 2016 Jan;76:5970-5982.
Curiel TJ. Tyrosine phosphorylation regulates ERβ ubiquitination, protein turnover, and inhibition of breast cancer Oncotarget 2016 Jan;7:42585-42597.
Curiel TJ. Safety and Efficacy of Durvalumab (MEDI4736), an Anti-PD-L1 Immune Checkpoint Inhibitor, in Patients with Advanced Urothelial Bladder Cancer Journal of Clinical Oncology 2016 Jan;34:3119-3125.
Hurez V, Dao V, Liu A, Pandeswara S, Gelfond J, Sun L, Bergman M, Orihuela J, Galvan V, Padron A, Drerup J, Liu Y, Hasty P, Sharp ZD, Curiel TJ. Chronic mTOR inhibition in mice with rapamycin alters T, B, myeloid and innate lymphoid cells and gut flora and prolongs life of immune deficient mice. (In Press) Aging Cell 2015 Jan;14(6):945-956.
Curiel TJ. Immunotherapy for Ovarian Cancer Current Treatment Options in Oncology 2015 Jan;.
Curiel TJ. Sequential Intravesical Mitomycin plus Bacillus Calmette-Guerin for Non-Muscle Invasive Urothelial Bladder Carcinoma: Translational and Phase I Clinical Trial Clinical Cancer Research 2015 Jan;21:303-311.
Curiel TJ. Interventions to Slow Aging in Humans: Are We Ready? Aging Cell 2015 Jan;14:497-510.
Curiel TJ. Host miR-155 promotes tumor growth through a myeloid-derived suppressor cell-dependent mechanism Cancer Research 2015 Jan;75:519-531.
Curiel TJ. Prevention of carcinogen and inflammation-induced dermal cancer by oral rapamycin includes reducing genetic damage Cancer Prevention Research 2015 Jan;8:400-409.
Messer JC, Curiel TJ, Kamat AM, Svatek RS. Female gender is associated with a worse survival after radical cystectomy for urothelial carcinoma of the bladder: a competing risk analysis Urology 2014 Apr;83:863-867.
Curiel TJ, Cheng P, Mottram P, Alvarez X, Moons L, Evdemon-Hogan M, Wei S, Zou L, Kryczek I, Hoyle G, Lackner A, Carmeliet P, Zou W. Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer. PMID 15313886 Cancer Res 2004 Aug;64(16):5535-5538.
