Departments & Divisions
Shujie Zhao, MD
Assistant Professor/Research
Patients with pancreatic ductal adenocarcinoma that show an initial response to chemotherapy generally develop resistance during their course of therapy. Cancer cell undergo adaptive changes in response to stresses involves a phenotypic switch with cells undergoing an epithelial to mesenchymal transition and expressing stem cell markers. The consequences of this switch are resistant to chemotherapy and more invasive. We are focus on understanding the molecular basis of adaptive plasticity to provide new strategies by either inhibiting these adaptive responses or by identifying molecules that can be targeted to improve response to therapy.
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Professional Background
Education
- 1989 - MS - Medical Science - Shanxi Medical University
- 1982 - MD - Medicine - Shanxi Medical University
- Postdoctoral Fellowship - Moledular Endocrinology - Foundation pour Recherches Medicales, University of Geneva
- Postdoctoral Fellowship - Molecular and cell biology of pancreatic cancer - UTHSCSA, Department of Surgery
- Postdoctoral Fellowship - Bone Biology and Cancer Bone Metastasis - UTHSCSA, Department of Medicine
Appointments
- 6/2003 - Assistant Professor/Research - University of Texas Health Science Center at San Antonio, Medicine, San Antonio
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Instruction & Training
- 5/2006 - Present, Individual Instruction, UTHSCSA