Peng Zhang, Ph.D.

Assistant Professor/Research

Department of Cell Systems and Anatomy

Professional Background
Education
- 2012 - PhD - Genetics - University of Chinese Academy of Sciences
Training
- 2017 - Postdoctoral Associate - Hematology and Epigenetics - University of Miami Miller School of Medicine
- 2015 - Postdoctoral Research Fellow - Stem Cell - Indiana University School of Medicine
Research & Grants

My work currently focuses on the studies of cellular and molecular mechanisms of epigenetic regulators (e.g. ASXL1 and ASXL2) in normal hematopoiesis and malignant diseases. My long-term research goal is to provide the comprehensive understanding of the epigenetic regulators in hematopoietic stem cells and how alterations contribute to hematologic malignancies.
Publications

1. The role of ASXL1/2 and their associated proteins in malignant hematopoiesis

2. Chromatin regulator Asxl1 loss and Nf1 halpoinsufficiency cooperate to accelerate myeloid malignancy

3. Loss of ASXL1 in the bone marrow niche dysregulates hematopoietic stem cell fates

4. Loss of Asxl2 leads to myeloid malignancies in mice

5. Loss of Asxl1 alters self-renewal and cell fate of bone marrow stromal cell, leading to Bohring-Opitz-like syndrome in mice

Education