Programs
Departments & Divisions
Currently seeking Ph.D. students
Nu Zhang, Ph.D.
Associate Professor
Department of Microbiology, Immunology & Molecular Genetics
Dr. Zhang studies the mechanisms underlying the differentiation and retention of tissue resident memory T cells controlled by transforming growth factor-beta (TGF-B) signaling. In addition, we study the biology of CD8+ T cells under various settings, including autoimmunity, chronic infection and tumor immunity.
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Professional Background
Education
- 2005 - Ph.D. - Immunology - Duke University
- 2000 - B.S. - Biochemistry and Molecular Biology - Peking University, China
Highlights
Rising Research Superstars Award from Long School of Medicine, UTHSCSA, 2019
Faculty of the Year: Annual Award from Department of MIMG, UTHSCSA, 2017
Voelcker Young Investigator Award, 2015
University of Texas System Rising STARs Award, 2014
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Publications
Shruti Mishra, Wei Liao, Yong Liu, Ming Yang, Chaoyu Ma, Haijing Wu, Ming Zhao, Xin Zhang, Yuanzheng Qiu, Qianjin Lu and Nu Zhang. TGF-ß and Eomes control the homeostasis of CD8+ regulatory T cells. J. Exp. Med. 2021 Jan 4;218(1):e20200030. doi: 10.1084/jem.20200030.
https://doi.org/10.1084/jem.20200030
Yong Liu, Chaoyu Ma and Nu Zhang. Tissue-specific control of tissue resident memory T cells. Crit. Rev. Immunol. 2018 DOI:10.1615/CritRevImmunol. 2018025653
Chaoyu Ma, Shruti Mishra, Erika L. Demel, Yong Liu and Nu Zhang. TGF-ß controls the formation of kidney-resident T cells via promoting effector T cell extravasation. J. Immunol. 2017 Jan 15;198(2):749-756. doi: 10.4049/jimmunol.1601500.
Chaoyu Ma and Nu Zhang. Transforming growth factor-ß signaling is constantly shaping memory T cell population.Proc. Natl. Acad. Sci. U.S.A. 2015;Sep 1;112 (35): 11013-7. doi: 10.1073/ pnas. 1510119112.
Nu Zhang and Michael J. Bevan. Transforming growth factor-ß signaling controls the formation and maintenance of gut-resident memory T cells by regulating migration and retention. Immunity,2013 Oct 17;39 (4):687-96. doi: 10.1016/j.immuni.2013.08.019.
Nu Zhang and Michael J. Bevan. TGF-ß signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation. Nat Immunol. 2012 May 27; 13(7): 667-73. doi: 10.1038/ni.2319.
Nu Zhang and Michael J. Bevan. CD8+ T cells: foot soldiers of the immune system. Immunity. 2011 Aug; 35 (2): 161-168.