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Gail Tomlinson, MD, PhD

Contact

210-567-7477

tomlinsong@uthscsa.edu

For administrative calls, please contact:

Departments & Divisions

Institutes & Centers

Gail Tomlinson, M.D., Ph.D.

Division Chief, Pediatrics Hematology/Oncology

Co-Director, Population Science Program and Prevention

Greehey Distinguished Chair in the Genetics of Cancer

I am a pediatric cancer specialist with specific expertise in inherited cancer syndromes which affect children and adults.  In addition to providing care for children with cancer, I work with individuals and families who are at higher than average risk of cancer to provide personalized longitudinal surveillance plans to decrease risk or enhance early detection.  I also have a long -standing interest in pediatric liver tumors and rare cancers.

  • Professional Background

    Education

    • 1992 - Postdoctoral Fellowship - Pediatrics-Hematology/Oncology - University of Texas Southwestern Medical Center
    • 1989 - Postdoctoral Fellowship - Pediatrics-Hematology/Oncology - University of Texas M.D. Anderson Cancer Center
    • 1987 - Residency - Pediatrics - Children's Hospital National Medical Center
    • 1984 - MD - Medicine - George Washington University Medical School
    • 1982 - PhD - Biochemistry - Duke University
    • 1974 - BS - Biology (Summa Cum Laude) - Dickinson College

    Appointments

    • 1/2007 - Professor with Tenure - University of Texas Health Science Center at San Antonio, Pediatrics, San Antonio
    • 1/2007 - Division Chief, Pediatrics Hematology/Oncology - University of Texas Health Science Center at San Antonio, Pediatrics, San Antonio

  • Instruction & Training

    • 04/2007 - 12/2012, MEDI6067 Genetics and Genetic Epidemiology, UT Health San Antonio
    • 03/2007 - 04/2016, CSBL6069 Cancer Biology Core II, UT Health San Antonio
    • 11.2018 - present, Team-Based Learning - Cancer Genetic Counseling, UT Health San Antonio
    • 09/2017 - present, CIRC5007 Inherited Cancer Lecture (MS1) , UT Health San Antonio
    • 09/2017 - present, GSBS TSCI16067 Cancer Genetics , UT Health San Antonio
    • 09/2017 - present, CIRC5007 Mock Tumor Board (MS1) , UT Health San Antonio
    • 08/2017 - 09/2019 , UTRGV: Ethics and Genetics Panel Leader (MS1) , UT Health San Antonio
    • 2012 - present, Associate Director, Pediatric Hematology/Oncology Fellowship Program, UT Health San Antonio

  • Publications

      Journal Articles

      * 1.  Grimes AC, Chen Y, Bansal H, Aguilar C, Perez Prado L, Quezada G, Estrada J, Tomlinson GE. Genetic Markers for Treatment-Related Pancreatitis in a Cohort of Hispanic Children With Acute Lymphoblastic Leukemia Support Care Cancer 2020 May

      * 2.  Gad M, Langevin AM, Sugalski A, Tomlinson GE. Highly Aggressive Thoracic Desmoid Tumors in Adolescent Siblings With Fatal Outcomes in an FAP Kindred: A Need for Increased Vigilance and Intervention in At-Risk AYAs Fam Cancer 2020 Apr

      * 3.  Koczkowska M, Callens T, Tomlinson GE, Messaien LM, and many others. Clinical Spectrum of Individuals With Pathogenic NF1 Missense Variants Affecting p.Met1149, p.Arg1276, and p.Lys1423: Genotype-Phenotype Study in Neurofibromatosis Type 1 Hum Mutat 2020 Jan;41(1):299-315.

      * 4.  Haines K, Sarabia SF, Alvarez KR, Tomlinson G, Vasudevan SA, Heczey AA, Roy A, Finegold MJ, Parsons DW, Plon SE, Lopez-Terrada D. Characterization of pediatric hepatocellular carcinoma reveals genomic heterogeneity and diverse signaling pathway activation. Pediatr Blood Cancer 2019 Jul;66(7)

      * 5.  Ding YC, Adamson AW, Steele L, VanNess C, Su L, Bailis AM, John EM, Tomlinson G, Neuhausen SL. Discovery of Mutations in Homologous Recombination Genes in African-American Women with Breast Cancer. Familial Cancer 2018 Apr;17(2):187-195.

      * 6.  Janitz AE, Ramachandran G, Tomlinson GE, Krailo M, Richardson M, Spector L. Maternal and paternal occupational exposures and hepatoblastoma: results from the HOPE study through the Children‘s Oncology Group. J Expo Sci Environ Epidemiol 2017 Jul;27(4):359-364.

      * 7.  Achatz MI, Porter CC, Brugières L, Druker H, Frebourg T, Foulkes W, Kratz CP, Kuiper R, Hansford JR, Hernandez HS, Nathanson K, Kohlmann WK, Doros L, Onel K, Schneider K, Scollon S, Tabori U, Tomlinson GE, Evans G, Plon SE. Cancer Screening Recommendations and Clinical Management of Inherited Gastrointestinal Cancer Syndromes in Childhood. Clin Cancer Res 2017 Jul;23(13):e107-e114.

      * 8.  Kalish JM, Doros L, Hellman L, Hennekam RCM, Kuiper R, Mass SM, Maher E, Nichols KE, Plon SE, Porter CC, Rednam S, Schultz KAP, States LJ, Tomlinson GE, Zelley K, Druley TE. Surveillance Recommendations for Children with Overgrowth Syndromes and Predisposition to Wilms Tumors and Hepatoblastoma. Clin Cancer Res 2017 Jul;23(13):e115-e122.

      * 9.  Wasserman JD, Tomlinson GE, Druker H, Kamihara J, Kohlmann WK, Kratz CP, Nathanson KL, Paitler KW, Parareda A, Rednam SP, States LJ, Villani A, Walsh MF, Zelley K, Schiffman JD. Multiple Endocrine Neoplasia and Hyperparathyroid-Jaw Tumor Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood. Clin Cancer Res 2017 Jul;23(13):e123-e132.

      * 10. Rednam SP, Erez A, Druker H, Janeway KA, Kamihara J, Kohlmann WK, Nathanson KL, States LJ, Tomlinson GE, Villani A, Voss SD, Schiffman JD, Wasserman JD. Von Hippel-Lindau and Hereditary Pheochromocytoma/Paraganglioma Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood. Clin Cancer Res 2017 Jun;23(12):e68-e75.

      * 11. Sumazin P, Chen Y, Trevino L, Sarabia SF, Hampton OA, Patel K, Mistretta T-A, Zorman B, Thompson P, Heczey A, Comerford S, Wheeler DA, Chintagumpala M, Meyer R, Rakheja D, Finegold MJ, Tomlinson G, Parson DW, Lopez-Terrada D. Genomic Analysis of Hepatoblastoma Identifies Distinct Molecular and Prognostic Subgroups Hepatology 2017 Jan;65(1):104-121.

      * 12. Grimes A, Mirkeshti, N, Chatterjee B, Tomlinson G, Assanasen C. Paraneoplastic Galactorrhea in Childhood T-ALL: An Evaluation of Tumor- derived Prolactin J Pediatr Hematol Oncol 2017 Jan;39(1):e18-e20.

      * 13. Comerford SA, Hinnant EA, Chen Y, Bansal H, Klapproth S, Rakheja D, Finegold MJ, Lopez-Terrada D, O‘Donnell KA, Tomlinson GE, Hammer RE. Hepatoblastoma modeling in mice places Nrf2 within a cancer field established by mutant β-catenin JCI Insight 2016 Oct;1(16)

      * 14. Elzi DJ, Song M, Blackman B, Weintraub ST, Lopez-Terrada D, Chen Y, Tomlinson GE, Shiio Y. FGF19 functions as autocrine growth factor for hepatoblastoma. Genes and Cancer 2016 Apr;7(3-4):125-135.

      * 15. Mette LA, Saldivar AM, Poullard NE, Torres IC, Seth SG, Pollock BH, Tomlinson GE. Reaching high-risk underserved individuals for cancer genetic counseling by video-teleconferencing. J Community Support Oncol 2016 Apr;14(4):162-168.

      * 16. Wei C, Peng B, Han Y, Chen WV, Rother J, Tomlinson GE, Boland CR, Chaussabel M, Frazier ML, Amos CI. Mutations of HNRNPA0 and WIF1 predispose members of a large family to multiple cancers. Fam Cancer 2015 Jun;14(2)

      * 17. King EE, Qin Y, Toledo RA, Luo A, Ball E, Faucz FR, Janeway KA, Stratakis CA, Tomlinson GE, Dahia PL. Integrity of the pheochromocytoma susceptibility TMEM127 gene in patients with pediatric malignancies. Endocr Relat Cancer 2015 Jun;22(3):5-7.

      * 18. Piwkham D, Siriboonpiputtana T, Beuten J, Pakakasama S, Gelfond JA, Paisooksantivatana K, Tomlinson GE, Rerkamnuaychoke B. Mutation Screening and Association Study of the Folylpolyglutamate Synthetase (FPGS) Gene with Susceptibility to Childhood Acute Lymphoblastic Leukemia Asian Pac J Cancer Prev 2015;16(11):4727-4732.

      * 19. Chai X, Friebel TM, Singer CF, Evans DG, Lynch HT, Isaacs C, Garber JE, Neuhausen SL, Matloff E, Eeles R, Tung N, Weitzel JN, Couch FJ, Hulick PJ, Ganz PA, Daly MB, Olopade OI, Tomlinson M, Blum JL, Domchek SM, Chen J, Rebbeck TR. Use of risk-reducing surgeries in a prospective cohort of 1,499 BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat 2014 Nov;148(2):397-406.

      * 20. Turcotte LM, Georgieff MK, Ross JA, Feusner JH, Tomlinson GE, Malogolowkin MH, Krailo MD, Miller N, Fonstad R, Spector LG. Neonatal medical exposures and characteristics of low birth weight hepatoblastoma cases: a report from the Children's Oncology Group. Pediatr Blood Cancer 2014 Nov;61(11):2018-2023.

  • Clinical

    Board Certifications

    • 1992 - Hematology-Oncology - American Board of Pediatrics
    • 1988 - General Pediatrics - American Board of Pediatrics