Karthigayan Shanmugasundaram, PhD

My Scientific career has been devoted to study the molecular mechanism, regulation of key genes in cancer biology and drug development for the same for the past 16 years, of which I am working on Kidney cancer for more than 9 years. My major focus is on both metabolome and transcriptome in order to comprehensively characterize the metabolism of Kidney cancer. Currently working on reserach projects to understand role of NOX4 in promoting proliferation, pseudohypoxia through increased fumarate levels and fatty acid oxidation defects in RCC. 

Renal cancer; Uterine FIbroids; Oxidative stress; Metabolic singaling and targeted therapy-PROTACs