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Steven R Seidner, MD

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210-567-5202

seidner@uthscsa.edu

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Departments & Divisions

Research

Research profile

Steven R Seidner, MD

Professor and Pediatric Department Chair

Miss Eloise Alexander Chair in Pediatric Pulmonary and Critical Care

Dr. Steven Seidner, M.D. is Professor and Chair of the Department of Pediatrics.  He has been at UTHSCSA since 1989 and was Division Chief of Neonatal-Perinatal Medicine from 2000-2019.  His research has focused on pulmonary surfactant, lung maturational agents, bronchopulmonary dysplasia, patent ductus arteriosus, and mesenchymal stromal cell therapy to prevent lung injury.  He is a neonatologist in San Antonio, Texas who is currently affiliated with University Health System.

  • Professional Background

    Education

    • 1988 - Postdoctoral Fellowship - Neonatology - UCLA School of Medicine, Harbor-UCLA Medical Center
    • 1985 - Residency - Pediatrics - UCLA School of Medicine, Harbor-UCLA Medical Center
    • 1982 - MD - Medicine - University of Arizona School of Medicine
    • 1976 - BA - Chemistry - Cornell University

    Appointments

    • 4/2019 - Miss Eloise Alexander Chair in Pediatric Pulmonary and Critical Care - The University of Texas Health Science Center at San Antonio, Pediatrics, San Antonio
    • 1/2019 - Chair, Department of Pediatrics - The University of Texas Health Sciences Center at San Antonio, Pediatrics, San Antonio
    • 11/2009 - Neonatologist - University Medicine Associates, Pediatrics, San Antonio
    • 9/2002 - Professor with Tenure - The University of Texas Health Science Center at San Antonio, Pediatrics, San Antonio
    • 9/1996 - Associate Professor with Tenure - The University of Texas Health Science Center at San Antonio, Pediatrics, San Antonio
    • 8/1989 - Medical Staff Member - University HospitalSan Antonio
    • 8/1989 - Assistant Professor - The University of Texas Health Science Center at San Antonio, Pediatrics, San Antonio
    • 1/2001 - Chief, Division of Neonatal-Perinatal Medicine - The University of Texas Health Science Center at San Antonio, Pediatrics, San Antonio

  • Instruction & Training

    • 8/2008 - Present, Neonatal Thematic Journal Update, UTHSA
    • 7/2001 - Present, Pediatric Resident Didactic Conference, University of Texas Health Science Center
    • 7/1999 - Present, Neonatology Fellowship Program, University of Texas Health Science Center at San Antonio
    • 7/1996 - Present, Primary Care New Born Service, University Hospital
    • 7/1993 - Present, Perinatal Morbidity Case Conference, University Hospital
    • 1/1990 - Present, Neonatal Resuscitation Course, University Hospital
    • 7/1989 - Present, NICU Rotation, NICU, University Hospital

  • Research & Grants

    Research profile

    Grants

    Federal

    Funding Agency Canadian Health Research Institute subcontract from Ottawa Hospital Research Institute Title Therapeutic Potential of Stem Cells in Lung Injury Status Active Period 1/2015 - 12/2018 Role Co-Investigator Grant Detail

    Private

    Funding Agency Draeger Medical Title A Clinical Study to Evaluate the Safety and Effectiveness of the Infinity Acute Care System Workstation Neonatal Care Babylog VN500 Device in High-Frequency Oscillatory Ventilation (HFOV) Mode in Extremely Low Birth Weight (ELBW) Neonates Status Active Period 12/2015 - 5/2020 Role Co-Principal Investigator Grant Detail Multicenter trial of Draeger High Frequency Oscillatory Vent Funding Agency Ottawa Health Research Instittute Title Therapeutic Potential of Stem Cells in Lung Injury Status Active Period 10/2016 - 5/2020 Role Principal Investigator Grant Detail Funding Agency Ottawa Health Research Instittute from Stem Cell Network Title Therapeutic Potential of Stem Cells in Lung Injury Status Active Period 6/2014 - 12/2018 Role Principal Investigator Grant Detail Funding Agency University Health System Title Preterm Baboon Model Status Active Period 1/2018 - 12/2018 Role Principal Investigator Grant Detail Health System contract supporting Neonatal Translational Research

  • Publications

      Abstract

      Macias R, Moreira A, Siddiqui S, Wilson D, Johnson-Pais T, Gelfond J, Seidner SR, Mustafa S. Gene Expression Profiles of Endogenous Lung Mesenchymal Stromal Cells Following Postnatal Adaptation and Mechanical Ventilation; 2018 May. (EPAS).

      Seidner SR, Mobius M, Mustafa SB, McCurnin DC, Blanco CL, Freund D, Rudiger M, Thebaud B. Decreased Pressor Use and Fluid Requirements Following Intravenous Administration of Human Umbilical Cord Derived Mesenchymal Stem Cells to Preterm Baboons of Borderline Viability; 2017 May. (Peds Res).

      SR Seidner,M Mobius, SB Mustafa, DC McCurnin, CL Blanco, M Rudiger, B Thebaud. Intravenous Administration of Human Umbilical Cord Derived Mesenchymal Stem Cells Decreases Pressor Use and Fluid Requirements in Preterm Baboons of Borderline Viability; 2017 Feb. (Journal of Investigative Medicine; vol. 65).

      Siddiqui S, Mustafa SB, Vasquez MM, Werner S, Seidner SR. Mechanical Ventilation Alters the Differentiation Potential and Ultrastructure of Endogenous Lung Mesenchymal Stromal Cells; 2016 May. (E-PAS2016:3873.662).

      Mustafa S, Siddiqui SK, Vasquez M, Werner SL, Seidner SR. Effect of Mechanical Ventilation and Postnatal Adaptation on Endogenous Premature Lung Mesenchymal Stromal Cells; 2016 Feb. (RegenMed SA Conference February 11-12, 2016, San Antonio, TX).

      Siddiqui SK, Mustafa SB, Vasquez MM, Seidner SR. Effect of Mechanical Ventilation and Postnatal Adaptation on Mesenchymal Stromal Cells Isolated from Late Preterm Rabbit Lung; 2016 Jan. (Journal of Investigative Medicine).

      Sartaj K. Siddiqui, Shamim Mustafa, Margarita Vasquez, Sherry L. Werner, Steve Seidner. Mechanical Ventilation Alters the Differentiation Potential and Ultrastructure of Endogenous Lung Mesenchymal Stromal Cells; 2016 Jan. (Peds Res).

      Siddiqui SK, Mustafa S, Vasquez M, Werner SL, Seidner SR. Mechanical Ventilation alters the Differentiation Potential and Ultrastructure of Endogenous Lung MSC from Late Preterm Rabbit Lung; 2016 Jan. (American Academy of Pediatrics Meeting on Perinatal Research January 6-8, 2016, Indian Wells, CA).

      Journal Article

      Blanco CL, Gastaldelli A, Anzueto DG, Winter LA, Seidner SR, McCurnin DC, Liang H, Javors MA, DeFronzo RA, Musi N. Effects of intravenous AICAR (5-aminoinidazole-4-carboximide riboside) administration on insulin signaling and resistance in premature baboons, Papio sp. (Accepted) PLOS One 2018 Jan;13.

      McGill-Vargas L, Gastaldelli A, Liang H, Anzueto Guerra D, Johnson-Pais T, Seidner S, McCurnin D, Muscogiuri G, DeFronzo R, Musi N, Blanco CL. Hepatic Insulin Resistance and Altered Gluconeogenic Pathway in Premature Baboons Endocrinology 2017 Jan;158(5):1140-1151.

      Blanco CL, Mcgill-Vargas LL, Gastaldelli A, Seidner SR, McCurinin DC, Leland MM, Anzueto DG, Johnson MC, Liang H, DeFronzo RA, Musi N. Peripheral Insulin Resistance and Impaired Insulin Signaling Contribute To Abnormal Glucose Metabolism in Preterm Baboons Endocrinology 2015 Mar;156(3):813-823.

      Mustafa SB, Isaac, Seidner SR, Dixon PS, Henson BM, and DiGeronimo RJ. Experimental Lung Research. 40(8):380-91, 2014.. Mechanical stretch induces lung alpha-epithelial Na+ channel expression Experimental Lung Research 2014 Nov;40(8):380-391.

      Not Specified

      Seidner SR, Mobius, Marius, Mustafa SB, McCurnin DC, Blanco CL, Freund, Daniel, Rudiger, Mario, Thebaud, Bernard. Decreased Pressor Use and Fluid Requirements Following Intravenous Administration of Human Umbilical Cord Derived Mesenchymal Stem Cells to Preterm Baboons of Borderline Viability Pediatric Academic Society Meeting 2017 San Francisco, CA 2017 Jan;.

  • Clinical

    Board Certifications

    • American Board of Pediatrics/Neonatal-Perinatal
    • American Board of Pediatrics