Programs
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Daniel L. Saenz, PhD
Associate Professor
Daniel Saenz is an Assistant Professor and Medical Physicist in the Department of Radiation Oncology. His clinical focuses are on quality assurance, patient safety, and stereotactic radiosurgery. Academically, he isthe course director of RADI 6030 and mentors PhD students, DMP students, and medical physics residents. He also participates at the university level in interprofessional education at UTHSCSA. His research focuses include image-guidance techniques in lung SBRT including 4D-CBCT and intrafractional image guidance for motion compensation and adaptive radiotherapy. Also, he focuses on accurate and efficient forms of stereotactic radiosurgery including the treatment of multiple intracranial brain metastases with a single isocenter. This work also includes dosimetry applications for the quality assurance of dose delivery.
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Professional Background
Education
- 2014 - PhD - Medical Physics - University of Wisconsin-Madison
- 2011 - MS - Medical Physics - University of Wisconsin-Madison
- 2009 - BS - Physics - Rice University
Appointments
- 2/2017 - Assistant Professor/Clinical and Other - UT Health San Antonio, Radiation Oncology, San Antonio
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Instruction & Training
- 2/2017 - Present, Rotation Student Supervision, UT Health San Antonio
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Research & Grants
Grants
Private
Funding Agency BrainLab Title BrainLab MME 2.0 validation Status Active Period 2/2019 - 8/2019 Role Co-Investigator Grant Detail
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Publications
Abstract
Ghahremani, S, Dolormente, K, Ha CS, Livadiotis, G, Papanikolaou N, Rasmussen KH, Kirby NA, Saenz DL, Myers PA, Mavroidis P, Stathakis S. Sensitivity of Dose Volume Objectives On Radiation Therapy Optimization Algorithms; 2019 Jun. (Medical Physics; vol. 46, no. 6). Nicewonger, D, Stathakis S, Papanikolaou N, Kirby NA, Saenz DL, Myers PA, Fakhreddine, M, Rasmussen KH. Improvements in Efficiency and Accuracy for HDR Source Positioning Through the Use of a High Resolution Camera Localization System; 2019 Jun. (Medical Physics; vol. 46, no. 6). Rembish, J, Myers PA, Rasmussen KH, Kirby NA, Saenz DL, Mavroidis, P, Papanikolaou N, Kabat, C, Bice, N, Stathakis S. Developing An Automated Method for Pre-Treatment Data Transfer Checks; 2019 Jun. (Medical Physics; vol. 46, no. 6). Bry, V, McCulloch, J, Rembish, J, Papanikolaou N, Crownover RL, Kirby NA, Saenz DL, Myers PA, Stathakis S, Rasmussen KH. Comparing the Accuracy of Surface Guided Imaging to Orthogonal X-Rays for Stereotactic Radiosurgery; 2019 Jun. (Medical Physics; vol. 46, no. 6). Licon, A, Stathakis S, Kirby NA, Rasmussen KH, Saenz DL, Papanikolaou N, Myers PA. Effect of Photon Energy on Whole Brain Radiation Therapy; 2019 Jun. (Medical Physics; vol. 46, no. 6). Kabat, C, Mavroidis, P, Parenica, H, Nicewonger, D, Defoor, D, Rasmussen KH, Myers PA, Saenz DL, Kirby NA, Stathakis S, Papanikolaou N. A Flexibel Radiobiological Tool for the Evaluation of Radiotherapy Treatment Plans; 2019 Jun. (Medical Physics; vol. 46, no. 6). Rembish, J, Myers PA, Rasmussen KH, Kirby NA, Saenz DL, Bry, V, Mavroidis, P, Papanikolaou N, Stathakis S. Evaluating the Effects of Varying Statistical Uncertainity Using a Monte Carlo Based Treatment Planning System; 2019 Jun. (Medical Physics; vol. 46, no. 6). Baley, C, Stathakis S, Myers PA, Kirby NA, Rasmussen KH, Papanikolaou N, Saenz DL. Validation of Simulated Target Motion Spatial Accuracy of Elekta Symmetry Versus 4D CT; 2019 Jun. (Medical Physics; vol. 46, no. 6). Myers PA, Kabat, C, Saenz DL, Rasmussen KH, Kirby NA, Papanikolaou N, Stathakis S. A Software Tool to Harvest and Analyze MLC Log Files of the Elekta VersaHD Linear Accelerator; 2019 Jun. (Medical Physics; vol. 46, no. 6). Martin, T, Saenz DL, Myers PA, Rasmussen KH, Stathakis S, Papanikolaou N, Kirby NA. An Easy to Create In-House Phantom for TG-132 Deformable Image Registration Evaluation; 2019 Jun. (Medical Physics; vol. 46, no. 6). Saenz DL, McCulloch, J, Rasmussen KH, Kirby NA, Myers PA, Stathakis S, Papanikolaou N. On the Spatial Accuracy of Single Isocenter Multiple Brain Metastases SRS with BrainLab Elements; 2019 Jun. (Medical Physics; vol. 46, no. 6). Delgado, AB, Rasmussen KH, Kauweloa, K, Pesqueira , Medrano T, Cohen, D, Eng T, Kirby NA, Saenz DL, Shi Z, Stathakis S, Papanikolaou N, Gutierrez, A. A Graphical User Interface GUI toolkit for Treatment Plan Quality Analysis in Right Lung SBRT; 2019 Jun. (Medical Physics; vol. 46, no. 6). Parenica, H, Kabat, C, Kirby NA, Rasmussen KH, Saenz DL, Mavroidis, P, Papanikolaou N, Stathakis S. Treatment Delivery Verification Using ELEKTA Versa HD High-Resolution Log Files; 2019 Jun. (Medical Physics; vol. 46, no. 6). Bales, K, George, R, Naessig, M, Fischer, K, Papanikolaou N, Kirby NA, Myers PA, Saenz DL, Rasmussen KH, Stathakis S. Dosimetric Evaluation of Electron Beam Doses at Various Interfaces; 2019 Jun. (Medical Physics; vol. 46, no. 6). McCulloch, J, Bry, V, Papanikolaou N, Saenz DL, Myers PA, Kirby NA, Stathakis S, Rasmussen KH. Quantifying the Effect of Eye Movement on Surface Guided Imaging for Stereotactic Radiosurgery; 2019 Jun. (Medical Physics; vol. 46, no. 6). Yu, V, Lee, C, Tenn, S, O`Connell, D, Weinstein, L, Skinner, M, McGuinness, C, Saenz DL, Papanikolaou N, Agazaryan, N. Use and Validation of IAEA Correction Factors for Small Field Dosimetry Commissioning: A Multi-Institution Study; 2019 Jun. (Medical Physics; vol. 46, no. 6). Kabat, C, Solis, J, Schantz, T, Graham, B, Defoor, D, Myers PA, Kirby NA, Rasmussen KH, Saenz DL, Jones, W, Mavroidis, P, Papanikolaou N, Stathakis S. An Ideal Planning Assistant Application for Planning Guidance and Patient Review in Radiotherapy; 2019 Jun. (Medical Physics; vol. 46, no. 6). Parenica H, Kabat, C, Fischer, K, Kirby NA, Rasmussen KH, Saenz DL, Myers PA, Mavroidis, P, Papanikolaou N, Stathakis S. Monte Carlo Modeling and Patient Dose Calculation Using DOSXYZnrc for the Elekta Versa HD with the Agility Collimator; 2019 Jun. (Medical Physics; vol. 46, no. 6). Stathakis S, Papanikolaou N, Kirby NA, Rasmussen KH, Saenz DL. ChartAlert: Automation for Physics Weekly Patient Chart Checks in Radiation Oncology; 2018 Jun. (Medical Physics; vol. 45, no. 6). Parencia, H, Kirby NA, Rasmussen KH, Saenz DL, Fakhreddine, M, Papanikolaou N, Stathakis S. Monte Carlo Modeling of the Elekta Versa HD with the Agility Collimator; 2018 Jun. (Medical Physics). Licon, A, Rembish, J, Crownover RL, Saenz DL, Kirby NA, Rasmussen KH, Papanikolaou N, Stathakis S. Feasibility of SRS Delivery for Single Mets Using the Versa HD Linac; 2018 Jun. (Medical Physics; vol. 45, no. 6). Saenz DL, Papanikolaou N, Kirby NA, Stathakis S, Rasmussen KH, Crownover RL, Floyd JR. Dosimetric Assessment of Spine SRS with the Brainlab Elements Treatment Planning System; 2018 Jun. (Medical Physics; vol. 45, no. 6). Astorga, N, Rasmussen KH, Kirby NA, Roring, J, Stathakis S, Saenz DL, Crownover RL, Papanikolaou N, George R. Design of a Real Time Online Tracking Solution for HDR Inventory; 2018 Jun. (Medical Physics). Bedre, M, Alexandrian, A, Papanikolaou N, Stathakis S, Sampson AJ, Rasmussen KH, Saenz DL, Kirby NA. An Open-Source Image Quality Assurance Software for Matlab/Octave; 2018 Jun. (Medical Physics; vol. 45, no. 6). Rembish, J, Saenz DL, Mavroidis, P, Crownover RL, Myers PA, Papanikolaou N, Stathakis S. Is Monte Carlo Necessary for IntraCranial Stereotactic Radiosurgery?; 2018 Jun. (Medical Physics; vol. 45, no. 6). Rembish, J, Mal,M, Kabat, C, Nunez, F, Kirby NA, Saenz DL, Rasmussen KH, Parenica, H, Papanikolaou N, Stathakis S. Rapid Database Parsing for Compressed Pinnacle Patient Files; 2018 Jun. (Medical Physics; vol. 45, no. 6). McCulloch, J, Rasmussen KH, Roring, J, Kabat, C, Stanley, D, Licon, A, Crownover RL, Shi Z, Kirby NA, Saenz DL, Stathakis S, Papanikolaou N. Is Surface Imaging Practical for 4D Gating On Animal Patients: A Feasibility Study; 2018 Jun. (Medical Physics; vol. 45, no. 6). Parenica, H, Rembish, J, Saenz DL, Rasmussen KH, Kirby NA, Shi Z, Li Y, Fakhreddine, M, Crownover RL, Ha CS, Papanikolaou N, Stathakis S. Comparison of Collapsed Cone Convolution Superposition and Monte Carlo Dose Calculations for Spine SBRT Dose; 2018 Jun. (Medical Physics; vol. 45, no. 6). Bassiri, N, McCulloch, J, Shi Z, Stathakis S, Saenz DL, Kirby NA, Papanikolaou N, Rasmussen JW. Quantification of Standard and FFF Beam Perturbations with a New Linac Mounted Transmission Detector; 2018 Jun. (Medical Physics; vol. 45, no. 6). Parenica, H, Rembish, J, Saenz DL, Rasmussen KH, Kirby NA, Shi Z, Li Y, Fakhreddine, M, Crownover RL, Ha CS, Papanikolaou N, Stathakis S. Comparison of Collapsed Cone Convolution Superposition and Monte Carlo Dose Calculations for Spine SBRT Dose; 2018 Jun. (Medical Physics; vol. 45, no. 6). Saenz DL, Papanikolaou N, Rasmussen KH, Kirby NA, Stathakis S, Pappas, E, Li Y. Quality Assurance for Multi-Focal Single Isocenter Stereotactic Radiosurgery Through 3D Gel Dosimetry; 2018 Jun. (Medical Physics; vol. 45, no. 6). George, R, Saenz DL, Kirby NA, Rasmussen KH, Stathakis S, Papanikolaou N. A Dosimetric Comparison of ICVI Varian Cones and BrainLab Cones; 2018 Jun. (Medical Physics; vol. 45, no. 6). Stathakis S, Licon, A, Saenz DL, Kirby NA, Rasmussen KH, Crownover RL, Li Y, Mavroidis, P, Papanikolaou N. Dynamic Conformal Arc Therapy for Lung and Liver SBRT; 2018 Jun. (Medical Physics; vol. 45, no. 6). Brito Delgado, A, Shi Z, Rasmussen KH, Medrano Pesqueira, T, Kauweloa, K, Cohen, D, Eng, T, Kirby NA, Saenz DL, Stathakis S, Papanikolaou N, Gutierrez, A. The Analytical Hierarchy Process (AHP) to Score Plan Quality of Lung SBRT Treatment Plans; 2018 Jun. (Medical Physics; vol. 45, no. 6). George, R, Stathakis S, Astorga, N, Kirby NA, Saenz DL, Rasmussen KH, Papanikolaou N. Retrospective Analysis of Plan-Of-The-Day Implementation for Prostate Cancer Patients; 2018 Jun. (Medical Physics; vol. 45, no. 6). Bassiri, N, Galvan, Eva, Crownover RL, Fakhreddine, M, Papanikolaou N, Saenz DL, Stathakis S, Kirby NA, Rasmussen KH. The Effect of Dose Inhomogeniety On Sarcoma HDR Treatments; 2018 Jun. (Medical Physics; vol. 45, no. 6). Astorga, N, Saenz DL, Kirby NA, Rasmussen KH, Stathakis S, Papanikolaou N. Pre-Treatment Table Coordinate Prediction for Improving Patient Safety in Radiation Therapy; 2018 Jun. (Medical Physics; vol. 45, no. 6). Ghahremani, S, Stanley,D, Papanikolaou N, Kirby NA, Rasmussen KH, Saenz DL, Jones W", Stathakis S. Institutional Experience of a Commercial Data Base System for Ongoing Daily/Weekly/Monthly QA of Linear Accelerators; 2018 Jun. (Medical Physics; vol. 45, no. 6). Rasmussen KH, Roring, J, Astorga, N, George, R, Stanley, DN, Stathakis S, Saenz DL, Gutierrez, AN, Shi Z, Papanikolaou N. Quantification of Signal Strength Variation Between OSLD Drawers; 2017 Jul. (Medical Physics). DN Stanley, K Mcconnell, Rasmussen KH, AN Gutierrez, Saenz DL, Stathakis S, Papanikolaou N, Kirby NA. Variability of Breast Surface Positioning for Deep Inspiration Breath Hold From An Active Breathing Coordinator; 2017 Jun. (Medical Physics; vol. 44, no. 6). R George, Stathakis S, Papanikolaou N, Saenz DL, Kirby NA, Rasmussen KH. Evaluation of the Effect of Body Habitus and Radiation Therapist On Initial Positioning of Prostate Patients; 2017 Jun. (Medical Physics; vol. 44, no. 6). Papanikolaou N, Saenz DL. Quality Assurance in MRI for Radiotherapy Planning; 2016 Sep. (Physica Medica; vol. 32, no. 3). Alexandrian, A, Kabat, C, Defoor, W, Saenz DL, Rasmussen KH, Kirby NA, Gutierrez AN, Papanikolaou N, Stathakis S. Tracking Trends of TG-142 Parameters Via Analysis of Data Recorded by 2D Chamber Array; 2016 Jun. (Med Phys; vol. 43, no. 6). Saenz DL, Gutierrez AN. Characterization of the Clinically Released ScandiDos Discover Diode Array for In-Vivo Dose Monitoring; 2016 Jun. (Medical Physics; vol. 43, no. 6). Stathakis S, Defoor, D, Saenz DL, Kirby NA, Mavroidis, P, Papanikolaou N. SRS Dose Calculation Accuracy Comparison Between Pencil Beam and Monte Carlo Algorithms; 2016 Jun. (Med Phys; vol. 43, no. 6). Saenz DL, Stathakis S. Differences in Lung Sparing in Deep Inspiration Breath-Hold and Free Breathing Breast Plans Calculated in Pinnacle and Monaco; 2016 Jun. (Medical Physics; vol. 43, no. 6). Yan Y, Du K, Saenz DL, Bassetti M, Harari PM, Paliwal B. A Soft Spectrum Filter to Improve the Dosimetric and Biologic Aspects of Flattening Filter Free TrueBeam; 2015 Oct. (Intl J Rad Onc Biol Phys; vol. 93, no. 3). Saenz DL, Yan Y, Ellefson S, Asprey W, Bayouth J, Paliwal B. Comparison of ViewRay 0.35 T MRI and Conventional CT Scans for Normal Structure Segmentation; 2015 Oct. (Intl J Rad Onc Biol Phys; vol. 93, no. 3). Roring J, Saenz DL, Cruz W, Papanikolaou N, Stathakis S. Analysis of Variability and Stability Between Two Water Tank Phantoms Utilizing Water Tank Commissioning Procedures; 2015 Jun. (Medical Physics; vol. 42, no. 6). Saenz DL, Kim H, Chen J, Stathakis S, Kirby N. Quality Assurance of Deformable Image Registration Algorithms: How Realistic Should Phantoms Be?; 2015 Jun. (Medical Physics; vol. 42, no. 6). Saenz DL, Narayanasamy G, Cruz W, Papanikolaou N, Stathakis S. End-To-End Dosimetric Testing of a Versa HD Linear Accelerator with the Agility Head Modeled in Pinnacle; 2015 Jun. (Medical Physics; vol. 42, no. 6). Paliwal B, Asprey W, Yan Y, Saenz DL, Bayouth J. Evaluation of ViewRay 0.35 T MRI Normal Structure Segmentation; 2015 Jun. (Medical Physics; vol. 42, no. 6). Yan Y, Saenz DL, Bayouth J, Paliwal B. Assessing the Consistency of the ViewRay 0.35 T MRI System; 2015 Jun. (Medical Physics; vol. 42, no. 6). Narayanasamy G, Saenz DL, Cruz W, Mavroidis P, Papanikolaou N, Stathakis S. Commissioning An Elekta VersaHD Linear Accelerator; 2015 Jun. (Medical Physics; vol. 42, no. 6). Saenz DL, Bayouth J, Christensen N, Henzler M, Forrest L, Paliwal B. ViewRay Real-Time Imaging of a Motion Phantom and In-Vivo Canine Patients; 2014 Jun. (Medical Physics; vol. 41, no. 6). Saenz DL, Bayouth J, Paliwal B. A Comparison of IMRT Plans for the ViewRay MR-Guided RT System with TomoTherapy and Pinnacle; 2013 Jun. (Medical Physics; vol. 40, no. 6). Chebrolu V, Dai J, Tewatia D, Yan Y, Saenz DL, Sethares W, Kissick M, Cannon G, Fain S, Paliwal B. Real-Time Automated Target Volume and Motion Quantification for Adaptive Four-Dimensional MRI/CT Guided Radiation Therapy; 2011 Oct. (Intl J Rad Onc Biol Phys; vol. 81, no. 2). Chebrolu V, Tewatia D, Dai J, Saenz DL, Sethares W, Fain S, Paliwal B. Four-Dimensional MRI/CT Based Auto-Adaptive Segmentation for Real-Time Radiotherapy in Lung Cancer Treatment; 2011 Jan. (Medical Physics; vol. 38, no. 6). Narayanasamy G, Bosse C, Saenz DL, Cruz W, Mavroidis P, Papanikolaou N, Stathakis S. Commissioning of Monaco Treatment Planning System On An Elekta VersaHD Linear Accelerator; 2001 Feb. (Medical Physics; vol. 42, no. 6).
Journal Article
Nicewonger D, Myers PA, Saenz DL, Kirby NA, Rasmussen KH, Papanikolaou N, Stathakis S. PTW QUICKCHECKwebline: Daily quality assurance phantom comparison and overall performance Journal of the Balkan Union of Oncology 2019 Aug;24(4):1727-1734. Kabat C, Defoor D, Myers PA, Kirby NA, Rasmussen KH, Saenz DL, Mavroidis P, Papanikolaou N, Stathakis S. Evaluation of the Elekta Agility MLC performance using high-resolution log files Medical Physics 2019 Jan;46(3):1397-1407. Saenz DL, Crownover RL, Stathakis S, Papanikolaou N. A dosimetric analysis of a spine SBRT specific treatment planning system J Appl Clin Med Phys 2019 Jan;20(1):154-159. Saenz DL, Li Y, Rasmussen K, Stathakis S, Pappas E, Papanikolaou N. Dosimetric and localization accuracy of Elekta high definition dynamic radiosurgery Physica Medica 2018 Oct;54:146-151. Saenz DL, Astorga NR, Kirby N, Fakhreddine M, Rasmussen K, Stathakis S, Papanikolaou N. A method to predict patient‐specific table coordinates for quality assurance in external beam radiation therapy Journal of Applied Clinical Medical Physics 2018 Sep;19(5):625-631. Saenz DL, Astorga NR, Kirby NA, Fakhreddine M, Rasmussen KH, Stathakis S, Papanikolaou N. A method to predict patient-specific table coordinates for quality assurance in external beam radiation therapy J Appl Clin Med Phys 2018 Sep;19(5):625-631. Narayanasamy G, Saenz DL, Defoor D, Papanikolaou N, Stathakis S. Dosimetric validation of Monaco treatment planning system on an Elekta VersaHD linear accelerator Journal of Applied Clinical Medical Physics 2017 Nov;18(6):123-129. Saenz DL, Kim H, Chen J, Stathakis S, Kirby NA. The level of detail required in a deformable phantom to accurately perform quality assurance of deformable image registration Physics in Medicine and Biology 2016 Aug;61(17):6269-6280. Saenz DL, Kirby NA, Gutierrez AN. Characterization of Air Temperature in Modern Ion Chambers Due to Phantom Geometry and Ambient Temperature Changes Medical Physics 2016 Jul;43(7):4032-4039. Narayanasamy G, Cruz W, Saenz DL, Stathakis S, Papanikolaou N, Kirby N. Effect of electron contamination on in vivo dosimetry for lung block shielding during TBI J Appl Clin Med Phys 2016 Jan;17(3):486-491. Saenz DL, Roring J, Cruz W, Sarkar V, Papanikolaou N, Stathakis S. Commissioning and cross-comparison of four scanning water tanks Journal of Cancer Therapy and Oncology 2015 Dec;4(1):1-9. Narayanasamy G, Saenz DL, Cruz W, Ha CS, Papanikolaou N, Stathakis S. Commissioning An Elekta VersaHD Linear Accelerator J Appl Clin Med Phys 2015 Sep;17(1):1-13. Saenz, DL, Narayanasamy, G, Cruz, W, Papanikolaou N, Stathakis S. Pinnacle3 modeling and end-to-end dosimetric testing of a Versa HD linear accelerator with the Agility head and flattening filter-free modes J Appl Clin Med Phys 2015 Aug;17(1):1-15. Saenz DL, Yan Y, Christensen N, Henzler M, Forrest L, Bayouth J, Paliwal B. Characterization of a 0.35T MR system for phantom image quality stability and in vivo assessment of motion quantification J Appl Clin Med Phys 2015 Jun;16(6):1-11. Saenz DL, Paliwal B, Bayouth J. A dose homogeneity and conformity evaluation between ViewRay and pinnacle-based linear accelerator IMRT treatment plans J Med Phys 2014 Apr;39(2):64-70.
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Makris DN, Pappas EP, Zoros E, Papanikolaou N, Saenz DL, Kalaitzakis G, Zourari K, Efstathopoulos E, Maris TG, Pappas E. Characterization of a novel 3D printed patient specific phantom for quality assurance in cranial stereotactic radiosurgery applications Phys Med Biol 2019 May;64(10):1-11.