Hai Rao, Ph.D.

Abstract

Rao H, and Cheng H. A F box protein RCY1 and other ubiquitin ligases promote histone variant CSE4 turnover and genome stability; 2017 Jan. (Zomes IX: PCI complexes and ubiquitin defining Hub for protein homeostasis). Rao H. Ub-mediated proteolysis in DNA repair; 2016 Jan. (Second conference on advances in cell biology).

Journal Article

Cheng, H., Hu, G., Luo, S., Gan, X., and Rao, H. A simple PCR-based strategy for the introduction of point mutations in the yeast S. cerevisiae via CRISPR/CAS9 Biochem Mol Biol J 2018 Feb;4(9). Cheng, H., Bao, X., Gan, X., Luo, S. and Rao, H. Multiple E3s promote the degradation of Histone variant Cse4 Scientific Reports 2017 Aug;7. Shao J., Xu L., Chen L., Lu Q., Xie X., Shi W., Xiong W., Shi C., Huang X., Mei J., Rao H, Lu H., Lu N., Luo S. The small G-protein Arl13b promotes tumorigenesis by regulating Smoothened trafficking and subsequent Hedgehog signaling pathway activation Cancer Research 2017 Jun;. Zhou F, Huang D, Li Y, Hu G, Rao H, Lu Q, Luo S, Wang Y. Nek2A/SuFu feedback loop regulates Gli-mediated Hedgehog signaling pathway International Journal of Oncology 2017 Feb;. Peng H, Yang J, Li G, You Q, Han W, Li T, Gao D, Xie X, Lee BH, Du J, Hou J, Zhang T, Rao H, Huang Y, Li Q, Zeng R, Hui L, Wang H, Xia Q, Zhang X, He Y, Komatsu M, Dikic I, Finley D, Hu. Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress Cell Research 2017 Jan;27. Klionsky DJ, ....Kumar AP.... et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Autophagy 2016 Jan;12(1):1-222. Rao H. Nek2A phosphorylates and stabilizes SuFu: A new strategy of Gli2/Hedgehog signaling regulatory mechanism Cellular signaling 2016 Jan;28:1304-1313. Rao H. The F box protein Rcy1 is involved in the degradation of Histone variant Cse4 and genome maintenance J. Biol. Chem 2016 Jan;291:10372-10377. Rao H. Rad25 protein is targeted for degradation by the Ubc4-Ufd4 pathway J. Biol Chem 2015 Jan;290:8606-8612. Rao H. Inhibition of Hedgehog signaling pathway impedes cancer cell proliferation by promotion of autophagy Euro. J. Cell Biol 2015 Jan;94:223-233. Shao J, Choe V, Cheng H, Tsai YC, Weissman AM, Luo S, Rao H. Ubiquitin ligase gp78 targets unglycosylated prion protein PrP for ubiquitylation and degradation PLoS One 2014 Apr;9(4).