Faculty Directory
Instructor/Research
2024 - Ebrahimi B, Viswanadhapalli S, Pratap UP, Rahul G, Yang X, Pitta Venkata P, Drel V, Santhamma B, Konda S, Li X, Sanchez ALR, Yan H, Sareddy GR, Xu Z, Singh BB, Valente PT, Chen Y, Lai Z, Rao M, Kost ER, Curiel T, Tekmal RR, Nair HB, Vadlamudi RK. Pharmacological inhibition of the LIF/LIFR autocrine loop reveals vulnerability of ovarian cancer cells to ferroptosis. NPJ Precis Oncol. 8(1):118. doi: 10.1038/s41698-024-00612-y.
2024 - Chen Y, Johnson JD, Jayamohan S, He Y, Venkata PP, Jamwal D, Alejo S, Zou Y, Lai Z, Viswanadhapalli S, Vadlamudi RK, Kost E, Sareddy GR. KDM1A/LSD1 inhibition enhances chemotherapy response in ovarian cancer. Mol Carcinog. 63(10):2026-2039. doi: 10.1002/mc.23792.
2023 - Venkata PP, Jayamohan S, He Y, Alejo S, Johnson JD, Palacios BE, Pratap UP, Chen Y, Liu Z, Zou Y, Lai Z, Suzuki T, Viswanadhapalli S, Weintraub ST, Palakurthi S, Valente PT, Tekmal RR, Kost ER, Vadlamudi RK, Sareddy GR. Pharmacological inhibition of KDM1A/LSD1 enhances estrogen receptor beta-mediated tumor suppression in ovarian cancer. Cancer Lett. 575:216383. doi: 10.1016/j.canlet.2023.216383.
2023 - Salvador Alejo, Bridgitte E. Palacios, Prabhakar Pitta Venkata, Yi He, Wenjing Li, Jessica D. Johnson, Yihong Chen, Uday P. Pratap, Sridharana Jayamohan, Kyra Clarke, Yi Zou, Suryavathi Viswanadhapalli, Zhao Lai, Zhenqing Ye, Yidong Chen, Andrea R. Gilbert, Takayoshi Suzuki, Rajeshwar R. Tekmal, Weixing Zhao, Siyuan Zheng, Ratna K. Vadlamudi, Andrew J. Brenner, Gangadhara R. SareddyLysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double strand break repair and augments efficacy of temozolomide in glioblastoma. Neuro Oncology, https://doi.org/10.1093/neuonc/noad018.
2022 - Yi He, Salvador Alejo, Prabhakar Pitta Venkata, Jessica D. Johnson, Ilanna Loeffel, Uday P. Pratap, Yi Zou, Zhao Lai, Rajeshwar R. Tekmal, Edward R. Kost, Gangadhara R. Sareddy. Therapeutic Targeting of Ovarian Cancer Stem Cells Using Estrogen Receptor Beta Agonist. Int. J. Mol. Sci. 23(13), 7159.
2021 - Prabhakar Pitta Venkata, Yihong Chen, Salvador Alejo, Yi He, Bridgitte E Palacios, Ilanna Loeffel, Junhao Liu, Uday P Pratap, Gabrielle Gray, Sureshkumar Mulampurath Achuthan Pillai, Yi Zou, Zhao Lai, Takayoshi Suzuki, Suryavathi Viswanadhapalli, Srinath Palakurthi, Rajeshwar R Tekmal, Ratna K Vadlamudi, Edward Kost, Gangadhara R Sareddy. KDM1A inhibition augments the efficacy of rapamycin for the treatment of endometrial cancer. Cancer Letters. 524, 219-231.
2021 - Weiwei Tang, Kumaraguruparan Ramasamy, Sureshkumar Pillai, Bindu Santhamma, Swapna Konda, Prabhakar Pitta Venkata, Logan Blankenship, Junhao Liu, Zexuan Liu, Kristin A Altwegg, Behnam Ebrahimi, Uday P Pratap, Xiaonan Li, Philip T Valente, Edward Kost, Gangadhara R Sareddy, Ratna K Vadlamudi, Hareesh B Nair, Rajeshwar R Tekmal, Suryavathi Viswanadhapalli. LIF/LIFR oncogenic signaling is a novel therapeutic target in endometrial cancer. Cell death discovery. 7 (1), 1-10.
2021 - Gangadhara R. Sareddy, Uday P. Pratap, Prabhakar Pitta Venkata, Mei Zhou, Salvador Alejo, Suryavathi Viswanadhapalli, Rajeshwar R. Tekmal, Andrew J. Brenner, Ratna K. Vadlamudi. Activation of estrogen receptor beta signaling reduces stemness of glioma stem cells. Stem Cells. 39 (5), 536-550.
2021 - Uday P Pratap, Gangadhara R Sareddy, Zexuan Liu, Prabhakar Pitta Venkata, Junhao Liu, Weiwei Tang, Kristin A Altwegg, Behnam Ebrahimi, Xiaonan Li, R R Tekmal, Suryavathi Viswanadhapalli, Stanton McHardy, Andrew J Brenner, Ratna K Vadlamudi. Histone deacetylase inhibitors enhance estrogen receptor beta expression and augment agonist-mediated tumor suppression in glioblastoma, Neuro-Oncology Advances, Volume 3, Issue 1.
2020 - Mei Zhou*, Prabhakar Pitta Venkata*, Suryavathi Viswanadhapalli, Bridgitte Palacios, Salvador Alejo, Yihong Chen, Yi He, Uday P. Pratap, Junhao Liu, Yi Zou, Zhao Lai, Takayoshi Suzuki, Andrew J. Brenner, Rajeshwar R. Tekmal, Ratna K. Vadlamudi & Gangadhara R. Sareddy. KDM1A inhibition is effective in reducing stemness and treating triple negative breast cancer. Breast Cancer Res Treat. 185, 343–357 *Equal first author.
2020 - Yiliao Luo, Mengxing Li, Uday P. Pratap, Suryavathi Viswanadhapalli, Junhao Liu, Prabhakar P. Venkata, Kristin A. Altwegg, Bridgitte E. Palacios, Xiaonan Li, Yihong Chen, Manjeet K. Rao, Andrew J. Brenner, Gangadhara R. Sareddy, Ratna K. Vadlamudi. PELP1 signaling contributes to medulloblastoma progression by regulating the NF‐κB pathway. Molecular Carcinogenesis. 59: 281– 292.
2019 - Gangadhara R Sareddy, Uday P Pratap, Suryavathi Viswanadhapalli, Prabhakar Pitta Venkata, Binoj C Nair, Samaya Rajeshwari Krishnan, Siyuan Zheng, Andrea R Gilbert, Andrew J Brenner, Darrell W Brann, Ratna K Vadlamudi. PELP1 promotes glioblastoma progression by enhancing Wnt/β-catenin signaling, Neuro-Oncology Advances. Volume 1, Issue 1.
2019 - Zhou M, Sareddy GR, Li M, Liu J, Luo Y, Venkata PP, Viswanadhapalli S, Tekmal RR, Brenner A, Vadlamudi RK. Estrogen receptor beta enhances chemotherapy response of GBM cells by down regulating DNA damage response pathways. Sci Rep. 9(1):6124.
Complete list of Publications:
https://scholar.google.co.in/citations?user=_i55E-oAAAAJ&hl=en