Ruben A Mesa, M.D.

• Professional Background

  Education

  • 2002 - Postdoctoral Fellowship - Hematology/Medical Oncology - Mayo Graduate School of Medicine, Mayo Clinic College of Medicine
  • 1998 - Residency - Internal Medicine - Mayo Graduate School of Medicine, Mayo Clinic College of Medicine
  • 1995 - MD - Medicine - Mayo Medical School, Mayo Clinic College of Medicine
  • 1991 - BS - Bioengineering - University of Illinois at Urbana-Champaign
  • 1991 - BS - Nuclear Engineering - University of Illinois at Urbana-Champaign

  Appointments

  • 8/2017 - Director - Mays Cancer Center at UT Health San Antonio MD AndersonSan Antonio
  • 8/2017 - Tenured Professor of Medicine - UT Health San AntonioSan Antonio
  • 8/2017 - Mays Family Foundation Distinguished University Chair - UT Health San AntonioSan Antonio

• Instruction & Training

  • 8/2016 - Present, Masters' Thesis Directed
  • 8/2015 - Present, Individual Instruction
  • 7/2015 - Present, Individual Instruction, Mayo Clinic
  • 12/2014 - Present, Individual Instruction, Mayo Clinic
  • 8/2012 - Present, Individual Instruction, Mayo Clinic
  • 1/2010 - Present, Individual Instruction, Mayo Clinic Graduate School of Medicine
  • 1/2010 - Present, Individual Instruction, Mayo Clinic Graduate School of Medicine
  • 10/2009 - Present, Individual Instruction
  • 6/2009 - Present, MCA Fellowship Academic Half Days, Mayo Clinic

• Research & Grants

  Research profile

  Grants

  Federal

  Funding Agency National Cancer Institute, NIH Title 2P01 CA108671 MPD Research Consortium, Project 4 Status Active Period 3/2018 - 2/2023 Role Co-Investigator Grant Detail The goals of Project 4 are to conduct, in patients with MPN, a series of hypothesis driven novel translational clinical trials, based on interactions with the core laboratory based projects (Projects 1-3) in order, to identify active new agents and approaches, including those based on individualized personal medicine, that act either alone or in combination, to change both the treatment paradigm and natural history of the disease leading to improve outcomes for patients. Funding Agency National Cancer Institute (NIH) Title UT Health San Antonio Cancer Center Support Grant Status Active Period 8/2017 - 7/2019 Role Principal Investigator Grant Detail Goal: This cancer center support grant provides research core and program infrastructure support to members of the cancer center for the conduct of their cancer-related research. 50% Effort-6 Months Funding Agency National Cancer Institute Title Yr 43 CCSG - Administration: Renewal Comprehensive Cancer Center Grant Status Active Period 3/2014 - 8/2017 Role Principal Investigator Grant Detail Admin, Pharmacy, Statistics, Sr. Leadership, PRMS, Bio-informatics Funding Agency National Cancer Institute Title Year 43 Mayo Comprehensive Cancer Center-CRO: Renewal Mayo Comprehensive Cancer Center-CRO Status Active Period 3/2014 - 8/2017 Role Principal Investigator Grant Detail   Funding Agency National Cancer Institute Title Yr 43 CCSG Bio-informatics: Renewal Comprehensive Cancer Center Grant Status Active Period 3/2014 - 8/2017 Role Principal Investigator Grant Detail Admin, Pharmacy, Statistics, Sr. Leadership, PRMS, Bio-informatics. Funding Agency National Cancer Institute Title Yr 43 CCSG - Biostatistics: Renewal Comprehensive Cancer Center Grant Status Active Period 3/2014 - 8/2017 Role Principal Investigator Grant Detail Admin, Pharmacy, Statistics, Sr. Leadership, PRMS, Bio-informatics. Funding Agency National Cancer Institute Title Yr 43 CCSG-PRMS: Renewal Comprehensive Cancer Center Grant Status Active Period 3/2014 - 8/2017 Role Principal Investigator Grant Detail Admin, Pharmacy, Statistics, Sr. Leadership, PRMS, Bio-informatics Funding Agency National Cancer Institute Title Yr 43 CCSG-Senior Leadership: Renewal Comprehensive Cancer Center Grant Status Active Period 3/2014 - 8/2017 Role Principal Investigator Grant Detail Admin, Pharmacy, Statistics, Sr. Leadership, PRMS, Bio-Informatics Funding Agency National Cancer Institute Title Yr 43 CCSG Status Active Period 3/2014 - 8/2017 Role Principal Investigator Grant Detail Admin, Pharmacy, Statistics, Sr. Leadership, PRMS, Bio-informatics Funding Agency National Cancer Institute Title Yr 43 CCSG Pharmacy: Renewal Comprehensive Cancer Center Grant Status Active Period 3/2014 - 8/2017 Role Principal Investigator Grant Detail Admin, Pharmacy, Statistics, Sr. Leadership, PRMS, Bio-Informatics Funding Agency National Cancer Institute Title National Clinical Trials Network U10 Lead Academic Site Status Active Period 5/2014 - 8/2017 Role Principal Investigator Grant Detail   Funding Agency National Cancer Institute Title MPD-RC (Myeloproliferative Diseases) Protocol 111-Tissue Status Complete Period 7/2011 - 6/2017 Role Principal Investigator Grant Detail   Funding Agency National Cancer Institute Title MPD Research Consortium, Project 6 Status Complete Period 7/2011 - 6/2017 Role Principal Investigator Grant Detail Full Project Number: P01 2P01 CA108671-05

  Private

  Funding Agency Gilead Sciences Title CTA Amend2 and 3 A Phase 3, Rand, Double-blind Active-controlled Study Eval Momelotinib vs. Ruxolitinib in Subjects with Primary Myelofibrosis (PMF) or Post-Polycythemia Vera or Post- Essential Thrombocythemia Myelofibrosis (Post-PV/ET MF) (more in detai Status Active Period 2/2014 - 1/2019 Role Principal Investigator Grant Detail CTA Amend 2 and 3 13-007635: A Phase 3, Rand, Double-blind Active-controlled Study Eval Momelotinib vs. Ruxolitinib in Subjects w/ Primary Myelofibrosis (PMF) or Post-Polycythemia Vera or Post- Essential Thrombocythemia Myelofibrosis (Post-PV/ET MF) Funding Agency Pfizer Inc. Title Lead in and Randomized Cohorts: 14-004331: A PHASE 2, DOUBLE-BLIND, RANDOMIZED SAFETY AND EFFICACY STUDY OF PF-04449913 VERSUS PLACEBO WITH DEFINED BEST SUPPORTIVE THERAPY ALLOWED IN BOTH ARMS IN PATIENTS WITH MYELOFIBROSIS PREVIOUSLY TREATED WITH ONE OR Status Active Period 11/2014 - 10/2018 Role Principal Investigator Grant Detail   Funding Agency Vanderbilt University Medical Center Title A Phase 1 Study of TGR-1202 Ruxolitinib in Subjects with Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (PPV-MF), Post-Essential Thrombocythemia MF (PET-MF), MDS/MPN, or Polycythemia Vera Resistant to Hydroxyurea: 16-003199/HEM 1538 Status Active Period 8/2016 - 8/2018 Role Principal Investigator Grant Detail   Funding Agency Incyte Title Randomized, open label, multicenter phase III study of Efficacy and Safety in Polycythemia Vera subjects who are resistant to or intolerant of hydroxyurea: JAK inhibitor INC 424 tablets versus best available care (The RESPONSE Tria (more in details) Status Active Period 8/2011 - 8/2018 Role Principal Investigator Grant Detail 11-002020 CTA Amendment 3 /CINC424B2301/ Randomized, open label, multicenter phase III study of Efficacy and Safety in Polycythemia Vera subjects who are resistant to or intolerant of hydroxyurea: JAK inhibitor INC 424 tablets versus best available care Funding Agency Cell Therapeutics, Inc (CTI) Title A Randomized controlled Phase 3 Study of Oral Pacritinib vs Best Available Therapy in Patients with PM, PPVM, or PETM: 14-000507 Status Active Period 6/2014 - 5/2018 Role Principal Investigator Grant Detail   Funding Agency Mayo Clinic: Hematology Title 16-006948/ Myeloproliferative Neoplasms and Acceptance and Commitment Therapy (The MYACT Trial) Status Active Period 4/2017 - 4/2018 Role Co-Investigator Grant Detail   Funding Agency Janssen Research and Development, LLC Title Part 2: 63935937MDS3001 A Study to Evaluate Imetelstat (JNJ-63935937) in Transfusion-Dependent Subjects with IPSS Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) that is Relapsed/Refractory to Erythropoiesis-Stimulating Agent (ESA) Treatment (m Status Active Period 4/2016 - 4/2018 Role Principal Investigator Grant Detail 15-007603 A Study to Evaluate Imetelstat (JNJ-63935937) in Transfusion-Dependent Subjects with IPSS Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) that is Relapsed/Refractory to Erythropoiesis-Stimulating Agent (ESA) Treatment Funding Agency Celgene Title A Phase 1, Open-Label, Dose Finding Study of CC-90002, a Monoclonal Antibody Directed Against CD47, in Subjects with Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome: 15-008009: (more in details) Status Active Period 3/2016 - 3/2018 Role Principal Investigator Grant Detail 15-008009 CTA and CTA Amend#1: A Phase 1, Open-Label, Dose Finding Study of CC-90002, a Monoclonal Antibody Directed Against CD47, in Subjects with Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome Funding Agency Gilead Sciences Title A Phase 2, Open-label, Translational Biology Study of Momelotinib in Transfusion-Dependent Subjects with Primary Myelofibrosis (PMF) or Post-polycythemia vera or Post-essential Thrombocythemia Myelofibrosis (Post-PV/ET MF) (more in details) Status Complete Period 12/2015 - 11/2017 Role Principal Investigator Grant Detail 15-005049 A Phase 2, Open-label, Translational Biology Study of Momelotinib in Transfusion-Dependent Subjects with Primary Myelofibrosis (PMF) or Post-polycythemia vera or Post-essential Thrombocythemia Myelofibrosis (Post-PV/ET MF) Funding Agency Pfizer Inc. Title Cross Over / Open Label: 14-004331: A PHASE 2, DOUBLE-BLIND, RANDOMIZED SAFETY AND EFFICACY STUDY OF PF-04449913 VERSUS PLACEBO WITH DEFINED BEST SUPPORTIVE THERAPY ALLOWED IN BOTH ARMS IN PATIENTS WITH MYELOFIBROSIS PREVIOUSLY TREATED WITH ONE OR MORE J Status Active Period 11/2014 - 8/2017 Role Principal Investigator Grant Detail   Funding Agency Gilead Sciences Title CTA Amend#2 Budget A2 MCA GS-1154 Open-label Study to Assess the Long-term Safety and Efficacy of Momelotinib in Subjects with Primary Myelofibrosis, Post-Polycythemia Vera, Post-essential Thrombocythemia Myelofibrosis, PV or ET: CTA Amend2 (protocol v2) Status Active Period 5/2014 - 8/2017 Role Principal Investigator Grant Detail 14-001644 GS-1154 - Open-label to Assess Long-term Safety and Effic of Momelotinib in Subj w Primary Myelofibrosis, Post-Polycythemia Vera, Post-essential Thrombo Myelofibrosis, Polycythemia Vera or Essential Thrombocythemia Funding Agency Incyte Title Prospective, Non-Interventional Study of Disease Progression and Treatment of Patients With Polycythemia Vera in United States Academic or Community Clinical Practices: 14-007140 Status Active Period 11/2014 - 8/2017 Role Principal Investigator Grant Detail   Funding Agency Cell Therapeutics, Inc (CTI) Title Intermediate Size Expanded Access ? Compassionate Use IND: 16-002598 Status Complete Period 4/2016 - 3/2017 Role Principal Investigator Grant Detail   Funding Agency PharmaEssentia Title Use of P1101 in Early Myelofibrosis: 14-001545 Status Complete Period 1/2015 - 12/2016 Role Principal Investigator Grant Detail   Funding Agency Celgene Title 10-003576/CC-4047-MF-002/ A PHASE-3, MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP STUDY TO COMPARE EFFICACY AND SAFETY OF POMALIDOMIDE IN SUBJECTS WITH MYELOPROLIFERATIVE NEOPLASM ?ASSOCIATED MYELOFIBROSIS AND RED BLOOD CELL Status Complete Period 8/2010 - 8/2016 Role Principal Investigator Grant Detail   Funding Agency Pfizer Inc. Title Patient-Reported Outcome Questionnaire for Use Among Patients with Myelofibrosis After First Line Treatment Failure: 15-001382 / Patient-Reported Outcome Questionnaire for Use Among Patients with Myelofibrosis After First Line Treatment Failure Status Complete Period 5/2015 - 4/2016 Role Principal Investigator Grant Detail   Funding Agency Cell Therapeutics, Inc (CTI) Title IRB#15-001735: Cognitive Interviews with Patients Diagnosed with Myelofibrosis. Status Complete Period 4/2015 - 3/2016 Role Principal Investigator Grant Detail   Funding Agency Gilead Sciences Title Protocol A-2 / Buget A-1 / A Phase 2, Open-label, Randomized Study to Evaluate the Safety and Efficacy of Momelotinib in Subjects with Polycythemia Vera or Essential Thrombocythemia: CTA Amend 1: 14-000756 - A Phase 2, Open-label, Randomized Study to Eva Status Complete Period 4/2014 - 3/2016 Role Principal Investigator Grant Detail   Funding Agency Gilead Sciences Title A Phase 2, Open-label, Randomized Study to Evaluate the Safety and Efficacy of Momelotinib in Subjects with Polycythemia Vera or Essential Thrombocythemia: 14-000756 - A Phase 2, Open-label, Randomized Study to Evaluate the Safety and Efficacy of Momelot Status Complete Period 4/2014 - 3/2016 Role Principal Investigator Grant Detail  

• Publications

  Abstract

  Mascarenhas J, Virtgaym E, Stal M, Blacklock H, Gerds AT, Mesa R, Ganly P, Snyder D, Tabbara I, Tremblay D, Moshier E. Outcomes of patients with myelofibrosis treated with compassionate use pacritinib: a sponsor-independent international study. doi: 10.1007/s00277-018-3309-6. Epub 2018 Apr 3. PMID:29616317; 2018 Aug. (Ann Hematol; vol. 97, no. 8). Leslie Padmos, Matthew Buras, Heidi Kosiorek, Robyn Scherber, Emily Knight, Andrea Cuc, Cynthia Stonnington, Amylou Dueck, Yonas Geda, Ruben Mesa. Myeloproliferative Neoplasms and Acceptance and Commitment Therapy: An Ongoing Feasibility Study Aimed at Symptom Mitigation and Quality of Life; 2018 Jun. (EHA Learning Center). Robyn Marie Scherber, Lindsey J. Whyte, Michelle Woehrle, Amylou C. Dueck, Srdan Verstovsek, Claire Harrison, Ruben A. Mesa. Creation and validation of the "myMPN" prospective patient registry of myeloproliferative neoplasm patients; 2018 Jun. Ruben A. Mesa, Giovanni Barosi, Claire N. Harrison, Jean-Jacques Kiladjian, Robert Peter Gale, Abderrahmane Laadem, Torsten Gerike, Peter G. Linde, Matthew L. Sherman, Joseph Pariseau, Srdan Verstovsek. A phase 2, multicenter, open-label study of the safety and efficacy of luspatercept in subjects with myeloproliferative neoplasm (MPN)-associated myelofibrosis and anemia with or without RBC transfusion dependence; 2018 Jun. Claire Harrison, Mary Frances McMullin, Anesh Panchal, Christina Yap, Sonia Fox, Rebecca Bishop, Natalia Curto-Garcia, Jason Coppell, John Laurie, Mamta Garg, Joanne Ewing, Steven Knapper, Josephine Crowe, Zor Maung, Anna Godfrey, Nicki Panoskaltsis, Robyn Scherber, Holly Geyer, Amylou Dueck, Ruben Mesa, Adam Mead. Ruxolitinib Compared With Best Available Therapy For Polycythaemia Vera Patients Resistant or Intolerant to Hydroxycarbamide in MAJIC-An Investigator-LED Randomised Trial; 2018 Jun. Holly Geyer, Robyn Scherber, Jeanne Palmer, Amylou Dueck, Marlene Girardo, Leslie Padmos, Ruben Mesa. Relationship Between MPN Pain and Emotional Health: An Analysis by the MPN Quality of Life International Study Group; 2018 Jun. Jennifer Huberty, Ryan Eckert, Linda Larkey, Krisstina Gowin, Jules Mitchell, Ruben Mesa. Qualitative Study Investigating The Perceptions of Myeloproliferative Neoplasm Patients Participating in an Online Yoga Intervention; 2018 Jun. Diaz AE, Mesa RA. Pacritinib and its use in the treatment of patients with myelofibrosis who have thrombocytopenia. doi: 10.2217/fon20170494. Epub 2017 Dec 13. PMID: 29235894; 2018 Apr. (Future Oncol; vol. 14, no. 9). Yu J, Parasuraman S, Paranagama D, Bai A, Naim A, Dubinski D, Mesa R. Impact of Myeloproliferative neoplasms on patients' employment status and work productivity in the United States: results from the living with MPNs survey. doi: 10.1186/s12885-018-4322-9. PMID:29653557; 2018 Apr. (BMC Cancer; vol. 18, no. 1). Jeanne Palmer, Heidi E. Kosiorek, Craig Zimmerman, Oleh Zagrijtschuk, John Camoriano and Ruben A. Mesa. Clinical Benefit of Ropeginterferon Alfa 2b (P1101) in Patients with Myelofibrosis; 2018 Jan. (Blood). Krisstina L. Gowin, Karen K. Ballen, Kwang Woo Ahn, Zhen-Huan Hu, Ying Liu, Lucia Masarova, Srdan Verstovsek, Maria Coakley, Tania Jain, Andrew Kuykendall, Rami Komrokji, Martha Wadleigh, Sarah Patches, Murat Arcasoy, Michael Green, Malathi Kandarpa, Moshe Talpaz, Haris Ali, Vikas Gupta, Rebecca Devlin, Laura C. Michaelis, Gabriela S. Hobbs, Brady Lee Stein, Ashley Pariser, Aaron T. Gerds, Kierstin Kuber, Raajit Rampal, Edwin P. Alyea III, Uday Popat, Ronald Sobecks, Bart L Scott, Ruben Mesa and Wael Saber. Survival Advantage to Allogeneic Transplant in Patients with Myelofibrosis with Intermediate-1 or Higher DIPSS Score; 2018 Jan. (Blood). John Mascarenhas, Heidi E. Kosiorek, Josef T. Prchal, Alessandro Rambaldi, Dmitriy Berenzon, Abdulraheem Yacoub, Claire N. Harrison, Mary Frances McMullin, Alessandro M. Vannucchi, Joanne Ewing, Casey L. O`Connell, Jean-Jacques Kiladjian, Adam J. Mead, Elliott F. Winton, David S. Leibowitz, Valerio De Stefano, Murat O. Arcasoy, Craig M. Kessler, Rosalind Catchatourian, Damiano Rondelli, Richard T. Silver, Andrea Bacigalupo, Arnon Nagler, Marina Kremyanskaya, Lonette Sandy, Mohamed E. Salama, Vesna Najfeld, Joseph Tripodi, Rona Singer Weinberg, Leah Price, Judith D Goldberg, Raajit K. Rampal, Ruben A. Mesa, Amylou C. Dueck and Ronald Hoffman. Results of the Myeloproliferative Neoplasms - Research Consortium (MPN-RC) 112 Randomized Trial of Pegylated Interferon Alfa-2a (PEG) Versus Hydroxyurea (HU) Therapy for the Treatment of High Risk Polycythemia Vera (PV) and High Risk Essential Thrombocyt; 2018 Jan. (Blood). Allison Gathany, Robyn M. Scherber, Marlene Girardo, Heidi E. Kosiorek, Amylou C. Dueck, Holly Geyer, Veena D. S. Fauble, Alessandro M. Vannucchi, Ana Kerguelen Fuentes, Christen Lykkegaard Andersen, Elisabeth Ejerblad, Gunnar Birgegard, Peter L. Johansson, Bjorn Andreasson, David M Ross, Federico Sackman, Jean-Loup Demory, Constantine S. Tam, Jan J. Michiels, Deepti Radia, Joanne Ewing, Frances Wadelin, Robert N. Lown, Mary Frances McMullin, Wunna Swe, Jonathan O. Cullis, Nigel Sargant, Paul Moreton, Catherine Cargo, Mallika Sekhar, Satareh Shekouhi and Ruben A. Mesa. Myeloproliferative Neoplasm Quality of Life (MPN-QOL) Study Group: MPN Experimental Assessment of Symptoms By Utilizing Repetitive Evaluation (MEASURE) Trial; 2018 Jan. (Blood). Ruben A. Mesa, Heidi E. Kosiorek, John Mascarenhas, Josef T. Prchal, Alessandro Rambaldi, Dmitriy Berenzon, Abdulraheem Yacoub, Claire N. Harrison, Mary Frances McMullin, Alessandro M. Vannucchi, Joanne Ewing, Casey L. O`Connell, Jean-Jacques Kiladjian, Adam J. Mead, Elliott F. Winton, David S. Leibowitz, Valerio De Stefano, Murat O. Arcasoy, Craig M. Kessler, Rosalind Catchatourian, Damiano Rondelli, Richard T. Silver, Andrea Bacigalupo, Arnon Nagler, Marina Kremyanskaya, Lonette Sandy, Mohamed E. Salama, Vesna Najfeld, Joseph Tripodi, Rona Singer Weinberg, Raajit K. Rampal, Ronald Hoffman and Amylou C. Dueck. Impact on MPN Symptoms and Quality of Life of Front Line Pegylated Interferon Alpha-2a Vs. Hydroxyurea in High Risk Polycythemia Vera and Essential Thrombocythemia: Results of Myeloproliferative Disorders Research Consortium (MPD-RC) 112 Global Phase III; 2018 Jan. (Blood). Jean-Jacques Kiladjian, Pierre Zachee, Masayuki Hino, Fabrizio Pane, Tamas Masszi, Claire N. Harrison, Ruben A. Mesa, Carole B. Miller, Francesco Passamonti, Simon Durrant, Martin Griesshammer, Keita Kirito, Carles Besses, Beatriz Moiraghi, Elisa Rumi, Vittorio Rosti, Igor W. Blau, Nathalie Francillard, Tuochuan Dong, Monika Wroclawska, Alessandro M. Vannucchi and Srdan Verstovsek. Long-Term Efficacy and Safety (5 Years) in RESPONSE, a Phase 3 Study Comparing Ruxolitinib (rux) with Best Available Therapy (BAT) in Hydroxyurea (HU)-Resistant/Intolerant Patients (pts) with Polycythemia Vera (PV); 2018 Jan. (Blood). Raajit K. Rampal, John Mascarenhas, Heidi E. Kosiorek, Rupali Bhave, Elizabeth O. Hexner, Eunice S. Wang, Aaron T. Gerds, Mark L Heaney, Camille N Abboud, Marina Kremyanskaya, Dmitriy Berenzon, Olatoyosi Odenike, Elizabeth Virtgaym, Lonette Sandy, Rona Singer Weinberg, Vesna Najfeld, Mohamed E. Salama, Ross L. Levine, Ruben A. Mesa, Amylou C. Dueck and Ronald Hoffman. Efficacy of Combined Ruxolitinib and Decitabine in Patients with Accelerated and Blast-Phase Myeloproliferative Neoplasms: Results of a Phase II Study (MPN-RC 109 trial); 2018 Jan. (Blood). Onima Chowdhury, Jennifer O`Sullivan, Nikolas Barkas, Gemma Buck, Angela Hamblin, Ayalew Tefferi, Haifa Al-Ali, Giovanni Barosi, Timothy Devos, Heinz Gisslinger, Qian Jiang, Jean-Jacques Kiladjian, Ruben A. Mesa, Francesco Passamonti, Vincent Ribrag, Gary J. Schiller, Alessandro M. Vannucchi, Daobin Zhou, Mary Frances McMullin, David Reiser, Jim Zhong, Robert Peter Gale and Adam J. Mead. Spliceosome Mutations Are Common in MPN-Associated Myelofibrosis with RBC-Transfusion-Dependence and Correlate with Response to Pomalidomide; 2018 Jan. (Blood). Srdan Verstovsek, Robert P. Hasserjian, Olga Pozdnyakova, Ivo Veletic, Ruben A. Mesa, Lynda Foltz, John Mascarenhas, Ellen K. Ritchie, Jeanne Palmer, Richard T. Silver, Marina Kremyanskaya, Bernt van den Blink, Renu Gupta, Taghi Manshouri, C. Cameron Yin, Zeev E. Estrov and Jason R. Gotlib. PRM-151 in Myelofibrosis: Efficacy and Safety in an Open Label Extension Study; 2018 Jan. (Blood). Stephen T Oh, Moshe Talpaz, Aaron T. Gerds, Vikas Gupta, Srdan Verstovsek, Ruben A. Mesa, Carole Brennan Miller, Candido E. Rivera, Angela Fleischman, Swati Goel, Mark L Heaney, Casey O`Connell, Murat Arcasoy, Yafeng Zhang, Jun Kawashima, Tomas Ganz and Carrie Baker Brachmann. Hepcidin Suppression By Momelotinib Is Associated with Increased Iron Availability and Erythropoiesis in Transfusion-Dependent Myelofibrosis Patients; 2018 Jan. (Blood). Zhenya Senyak, Ruben A. Mesa, Nicolaus Kroeger, Koen Van Besien, Wael Saber, Richard T. Silver, Attilio Orazi, Jeanne Palmer, Claire N. Harrison, Srdan Verstovsek, Uday Popat, Michelle J Woerhle, Ann Brazeau, Barbara Van Husen, Martin Prager, Chris Harper, Beatrice Larroque and Robyn Marie Scherber. Results from the Myeloproliferative Neoplasm Patient Care Survey: Patient Care Opportunities and Challenges; 2018 Jan. (Blood). Robyn M. Scherber, Holly L. Geyer, Gina Mazza, Blake T. Langlais, Amylou C. Dueck, Jeanne Palmer, Leslie Padrnos, Angela Fleischman and Ruben A. Mesa. Tobacco Use in the Myeloproliferative Neoplasms: Patient Behavior, Opinions, and Care; 2018 Jan. (Blood). Blake T. Langlais, Gina Mazza, Crystal S. Langlais, Heidi E. Kosiorek, Holly L. Geyer, Ruben A. Mesa, Robyn M. Scherber and Amylou C. Dueck. Utilization of Patient-Reported Outcomes in Myeloproliferative Neoplasm Clinical Trials Registered at Clinicaltrials.Gov; 2018 Jan. (Blood). Jeanne Palmer, Heidi E. Kosiorek, Christine Wolschke, Veena D. S. Fauble, Richard Butterfield III, Holly Geyer, Robyn M. Scherber, Amylou C. Dueck, Allison Gathany, Ruben A. Mesa and Nicolaus Kroeger. Assessment of Quality of Life Following Allogeneic Stem Cell Transplant for Myelofibrosis; 2018 Jan. (Blood). Srdan Verstovsek, Jingbo Yu, Jonathan K. Kish, Dilan Chamikara Paranagama, Jill Kaufman, Jessica Chung, Michael R. Grunwald, Philomena Colucci and Ruben A. Mesa. Real-World Risk Assessment and Treatment of Patients with Myelofibrosis at Community Oncology Practices in the United States; 2018 Jan. (Blood). Krisstina L. Gowin, Blake T. Langlais, Denise Millstine, Heidi E. Kosiorek, Jennifer Huberty, Ryan Eckert and Ruben A. Mesa. Survey of Integrative Medicine in Myeloproliferative Neoplasms (The SIMM Study-2); 2018 Jan. (Blood). Holly L. Geyer, Robyn M. Scherber, Gina Mazza, Blake Langlais, Leslie Padrnos, Jeanne Palmer, Amylou C. Dueck and Ruben A. Mesa. Prevalence and Risk Factors for Opioid-Related Complications in Patients with Myeloproliferative Neoplasms: An International Survey of 502 Patients By the MPN Quality of Life Study Group; 2018 Jan. (Blood). Ruben A. Mesa, Francisco Cervantes, Claire N. Harrison, Adam J. Mead, Alessandro M. Vannucchi, Srdan Verstovsek, Lixia Wang, Tanya Granston and John Mascarenhas. Pooled Analyses of Total Symptom Score (TSS) Responses in Patients with Myelofibrosis (MF) Treated with Pacritinib (PAC) Vs Best Available Therapy (BAT) in Phase 3 Studies (PERSIST-1, PERSIST-2); 2018 Jan. (Blood). Holly L. Geyer, Robyn M. Scherber, Gina Mazza, Blake T. Langlais, Ruben A. Mesa, Leslie Padrnos, Amylou C. Dueck and Jeanne Palmer. Addressing the Adequacy of Current MPN Pain Management Strategies: An International Survey of 502 Patients By the MPN Quality of Life Study Group; 2018 Jan. (Blood). Anas Al-Janadi, Ruben A. Mesa, Philomena Colucci, Shreekant Parasuraman, Dilan Chamikara Paranagama and Michael Richard Grunwald. Characteristics Associated with Hydroxyurea Treatment Change in Patients with Polycythemia Vera: An Analysis from the Reveal Study; 2018 Jan. (Blood). Ivy Altomare, Aaron T. Gerds, David Lessen, Philomena Colucci, Shreekant Parasuraman, Dilan Chamikara Paranagama and Ruben A. Mesa. Correlation between MPN-SAF TSS and EORTC QLQ-C30 Scores in Patients with PV: Data from the Reveal Study; 2018 Jan. (Blood). Mesa RA, Kiladjian JJ, Catalano JV, Devos T, Egyed M, Hellmann A, McLornan D, Shimoda K, Winton EF, Deng W, Dubowy RL, Maltzman JD, Cervantes F, Gotlib J. SIMPLIFY-1: A Phase III Randomized Trial of Momelotinib Versus Ruxolitinib in Janus Kinase Inhibitor-Naive Patients With Myelofibrosis. doi: 10.1200/JCO.2017.73.4418. Epub 2017 Sep 20. PMID:28930494; 2017 Dec. (J Clin; vol. 35, no. 34). Harrison CN, Koschmieder S, Foltz L, Guglielmelli P, Flindt T, Koehler M, Mathias J, Komatsu N, Boothroyd RN, Spierer A, Perez Ronco J, Taylor-Stokes G, Waller J, Mesa RA. The impact of myeloproliferative neoplasms (MPNs) on patient quality of life and productivity: results from the international MPN Landmark survey. doi: 10.1007/s002770173082y. Epub 2017 Aug 5. PMID: 28780729; 2017 Oct. (Ann Hematol; vol. 96, no. 10). Verstovsek S, Mesa RA, Salama ME, Li L, Pitou C, Nunes FP, Price GL, Giles JL, D'Souza DN, Walgren RA, Prchal JT. A phase 1 study of the Janus kinase 2 (JAK2)V617F inhibitor, gandotinib (LY2784544), in patients with primary myelofibrosis, polycythemia vera, and essential thrombocythemia. doi: 10.1016/j.leukres.2017.08.010. Epub 2017 Aug 31. PMID:28934680; 2017 Oct. (Leuk Res; vol. 61). Ellis MH, KorenMichowitz M, Lavi N, Vannucchi AM, Mesa R, Harrison CN. Ruxolitinib for the management of myelofibrosis: Results of an international physician survey. doi: 10.1016/j.leukres.2017.08.002. Epub 2017 Aug 10. PMID: 28843161; 2017 Oct. (Leuk Res; vol. 61). Geyer H, Mesa RA. Approach to MPN Symptom Assessment. doi: 10.1007/s1189901703995. Review. PMID: 28942516; 2017 Oct. (Curr Hematol Malig Rep; vol. 12, no. 5). Harrison CN, Mead AJ, Panchal A, Fox S, Yap C, Gbandi E, Houlton A, Alimam S, Ewing J, Wood M, Chen F, Coppell J, Panoskaltsis N, Knapper S, Ali S, Hamblin A, Scherber R, Dueck AC, Cross NCP, Mesa R, McMullin MF. Ruxolitinib vs best available therapy for ET intolerant or resistant to hydroxycarbamide. doi: 10.1182/blood201705785790. Epub 2017 Aug 9. PMID: 29074595; 2017 Oct. (Blood; vol. 130, no. 17). Pemmaraju N, Mesa RA, Majhail NS, Thompson MA. The use and impact of Twitter at medical conferences: Best practices and Twitter etiquette. doi: 10.1053/j.seminhematol.2017.08.003. Epub 2017 Aug 24. Review. PMID: 29153078; 2017 Oct. (Semin Hematol; vol. 54, no. 4). Verstovsek S, Courby S, Griesshammer M, Mesa RA, Brachmann CB, Kawashima J, Maltzman JD, Shao L, Xin Y, Huang D, Bajel A. A phase 2 study of momelotinib, a potent JAK1 and JAK2 inhibitor, in patients with polycythemia vera or essential thrombocythemia. doi: 10.1016/j.leukres.2017.05.002. Epub 2017 May 30. PMID: 28622623; 2017 Sep. (Leuk Res; vol. 60). Miller CB, Komrokji RS, Mesa RA, Sun W, Montgomery M, Verstovsek S. Practical Measures of Clinical Benefit With Ruxolitinib Therapy: An Exploratory Analysis of COMFORT-I. [Epub ahead of print] PMID:28606598 DOI:10.1016/j.clml.2017.05.015; 2017 Aug. (Clin Lymphoma Myeloma Leuk; vol. 17, no. 8). Harrison CN, Schaap N, Vannucchi AM, Kiladjian JJ, Tiu RV, Zachee P, Jourdan E, Winton E, Silver RT, Schouten HC, Passamonti F, Zweegman S, Talpaz M, Lager J, Shun Z, Mesa RA. Janus kinase-2 inhibitor fedratinib in patients with myelofibrosis previously treated with ruxolitinib (JAKARTA-2): a single-arm, open-label, non-randomised, phase 2, multicentre study. Epub 2017 June 08 PMID:28602585 DOI:10.1016/S2352-3026(17)30088-1; 2017 Jul. (Lancet Haematol; vol. 4, no. 7). Gowin K, Kosiorek H, Dueck A, Mascarenhas J, Hoffman R, Reeder C, Camoriano J, Tibes R, Gano K, Palmer J, Mesa R. Multicenter phase 2 study of combination therapy with ruxolitinib and danazol in patients with myelofibrosis. Epub 2017 June 13 PMID:28646676 DOI:10.1016/j.leukres.2017.06.005; 2017 Jun. (Leuk Res; vol. 60). Steffen Koschmieder, Michael Koehler, Paola Guglielmelli, Ruben A. Mesa, Lynda Foltz, Tina Flindt, Jonathan Mathias, Norio Komatsu, Robert N. Boothroyd, Amber Spierer, Julian Perez Ronco, Gavin Taylor-Stokes, John Waller, Claire N. Harrison. TREATMENT AND MANAGEMENT OF PATIENTS WITH MPNS?FINDINGS FROM THE INTERNATIONAL MPN LANDMARK SURVEY; 2017 Jun. Krisstina Gowin, Denise Millstine, Heidi Kosiorek, Blake Langlais, Jennifer Huberty, Ryan Eckert, Ruben Mesa. THE SIMM STUDY: SURVEY OF INTEGRATIVE MEDICINE IN MYELOPROLIFERATIVE NEOPLASMS; 2017 Jun. Suliman Al-Fayoumi, John Mascarenhas,Ronald Hoffman, Moshe Talpaz, Aaron T. Gerds, Brady Stein, Vikas Gupta, Anita Szoke, Mark Drummond, Alexander Pristupa, Huafeng Zhou, Robert Daly, Jennifer A. Callahan, Jack W. Singer, Jason Gotlib, Catriona Jamieson, Claire Harrison, Ruben Mesa, Srdan Verstovsek. PK/PD MODELING COMPARING DIVIDED DOSING (200 MG TWICE DAILY) VS SINGLE DOSING (400 MG ONCE DAILY) OF PACRITINIB IN PATIENTS WITH MYELOFIBROSIS ON THE PERSIST-2 PHASE 3 TRIAL; 2017 Jun. Jason R. Gotlib, Jean-Jacques Kiladjian, John V. Catalano, Timothy Devos, Miklos Egyed, Andrzei Hellman, Donal P. McLornan, Kazuya Shimoda, Elliott F. Winton, Wei Deng, Ronald L. Dubowy, Julia D. Maltzman, Francisco Cervantes, Ruben A. Mesa. PHASE 3 RANDOMIZED TRIAL OF MOMELOTINIB VERSUS RUXOLITINIB IN JAK INHIBITOR NAIVE PATIENTS WITH MYELOFIBROSIS: RESULTS OF THE SIMPLIFY-1 STUDY; 2017 Jun. Lynda Foltz, Steffen Koschmieder, Claire N. Harrison, Paola Guglielmelli, Tina Flindt, Michael Koehler, Jonathan Mathias, Norio Komatsu, Robert N. Boothroyd, Amber Spierer, Julian Perez Ronco, Gavin Taylor-Stokes, John Waller, Ruben A. Mesa. PERCEPTION OF SYMPTOM BURDEN AND TREATMENT GOALS BETWEEN PHYSICIANS AND PATIENTS WITH MPNS: AN ANALYSIS FROM THE INTERNATIONAL MPN LANDMARK SURVEY; 2017 Jun. Moshe Talpaz, John Mascarenhas, Ronald Hoffman, Aaron T. Gerds, Brady Stein, Vikas Gupta, Anita Szoke, Mark Drummond, Alexander Pristupa, Tanya Granston, Robert Daly, Suliman Al-Fayoumi, Jennifer A. Callahan, Jack W. Singer, Jason Gotlib, Catriona Jamieson, Claire Harrison, Ruben Mesa, Srdan Verstovsek. PACRITINIB (PAC) VS BEST AVAILABLE THERAPY (BAT), INCLUDING RUXOLITINIB, IN PATIENTS (PTS) WITH MYELOFIBROSIS (MF) AND BASELINE THROMBOCYTOPENIA: FOCUS ON ANEMIA IN THE PHASE 3 PERSIST-2 TRIAL; 2017 Jun. Claire Harrison, John Mascarenhas, Ronald Hoffman, Moshe Talpaz, Aaron T. Gerds, Brady Stein, Vikas Gupta, Anita Szoke, Mark Drummond, Alexander Pristupa, Tanya Granston, Robert Daly, Suliman Al-Fayoumi, Jennifer A. Callahan, Jack W. Singer, Jason Gotlib, Catriona Jamieson, Ruben Mesa, Srdan Verstovsek. PACRITINIB (PAC) VS BEST AVAILABLE THERAPY (BAT), IN PATIENTS WITH MYELOFIBROSIS (MF) AND BASELINE (BL) THROMBOCYTOPENIA: FOCUS ON RUXOLITINIB (RUX)-TREATED PATIENTS IN THE PHASE 3 PERSIST-2 TRIAL; 2017 Jun. Robyn Scherber, Holly Geyer, Amylou Dueck, Carol Johnston, Blake Langlais, Leslie Padrnos, Jeanne Palmer, Angela Fleischman, Ruben Mesa. NUTRITIONAL NEEDS AND PREFERENCES OF MYELOPROLIFERATIVE NEOPLASM PATIENTS: PHASE IA OF THE NUTRIENT STUDY; 2017 Jun. Robyn Scherber, Heidi Kosiorek, Holly Geyer, Srdan Verstovsek, Blake Langlais, Leslie Padrnos, Jeanne Palmer, Amylou Dueck, Angela Fleischman, Ruben Mesa. NUTRITION IN MYELOFIBROSIS: CORRELATES FROM THE COMFORT-1 STUDY; 2017 Jun. Jennifer Huberty , Ryan Eckert , Krisstina Gowin , Brenda Ginos , Heidi Kosiorek , Amylou Dueck , Linda Larkey , Ruben Mesa. DEVELOPMENT AND DESIGN OF A RANDOMIZED CONTROLLED TRIAL USING ONLINE YOGA FOR SYMPTOM MANAGEMENT IN MYELOPROLIFERATIVE NEOPLASM PATIENTS; 2017 Jun. Amylou Dueck , Robyn Scherber , Heidi Kosiorek , Blake Langlais , Leslie Padrnos , Jeanne Palmer , Srdan Verstovsek , Jeff Sloan , Geyer Holly , Ruben Mesa. DETERMINING MEANINGFUL CHANGE IN THE MYELOFIBROSIS SYMPTOM ASSESSMENT FORM (MFSAF) V2.0 USING A COMBINATION OF DISTRIBUTION- AND ANCHOR-BASED APPROACHES IN THE COMFORT-I TRIAL; 2017 Jun. Geyer H, Scherber R, Kosiorek H, Verstovesek S, Langlais B, Padrnos L, Palmer J, Dueck A, Mesa R. Correlations between inflammatory biomarkers and individual symptoms expressed by myelofibrosis patients in the COMFORT-I Trial: Analysis of baseline associations and changes over time; 2017 Jun. Robyn Scherber, Heidi Kosiorek, Holly Geyer, Srdan Verstovsek, Jeff Sloan, Blake Langlais, Leslie Padrnos, Jeanne Palmer, Angela Fleischman, Amylou Dueck, Ruben Mesa. BASELINE QUALITY OF LIFE INDEPENDENTLY PREDICTS OVERALL SURVIVAL IN THE MYELOFIBROSIS: KEY INSIGHTS FROM THE COMFORT-I STUDY; 2017 Jun. Gwaltney C, Paty J, Kwitkowski VE, Mesa RA, Dueck AC, Papadopoulos EJ, Wang L, Feliciano J, Coons SJ. Development of a harmonized patient-reported outcome questionnaire to assess myelofibrosis symptoms in clinical trials. [Epub ahead of print] PMID:28544906 DOI:10.1016/j.leukres.2017.05.012; 2017 May. (Leuk Res; vol. 59). Ryan Eckert, Jennifer Huberty, Amylou Dueck, Heidi Kosiorek, Linda Larkey, and Ruben A Mesa. A Pilot Study of Online Yoga to Improve Fatigue and Quality of Life in Myeloproliferative Neoplasm Patients; 2017 Jan. (Blood; vol. 130). Amylou C. Dueck, John Mascarenhas, Heidi Elizabeth Kosiorek, Abdulraheem Yacoub, Josef T. Prchal, Dmitriy Berenzon, Maria R. Baer, Ellen K Ritchie, Richard T Silver, Craig M. Kessler, Elliott F. Winton, Maria Chiara Finazzi, Alessandro Rambaldi, Alessandro M. Vannucchi, David S. Leibowitz, Damiano Rondelli, Murat O. Arcasoy, Rosalind Catchatourian, Joseph Vadakara, Vittorio Rosti, Elizabeth Hexner, Marina Kremyanskaya, Alicia Orellana, Lonette Sandy, Joseph Tripodi, Vesna Najfeld, Mohamed E. Salama, Rona Singer Weinberg, Raajit K. Rampal, Ronald Hoffman and Ruben A Mesa . Single-Arm Phase II Trial of Pegylated Interferon Alpha 2a in Patients with High-Risk Essential Thrombocythemia or Polycythemia Vera Resistant or Intolerant to Hydroxyurea: MPN Symptom Impact & Quality of Life Results of the Myeloproliferative Disorders; 2017 Jan. (Blood; vol. 130). Gowin KL, Millstine D, Kosiorek HE, Langlais B, Huberty J, Eckert R, Mesa RA. Supportive care and symptom burden in patients with myeloproliferative neoplasms. Abstract No 21684; 2017 Jan. (J Clin Oncol; vol. 35, no. Sup). Gerds AT, Tauchi T, Ritchie EK, Deininger MWN, Jamieson CHM, Mesa RA, Heaney ML, Komatsu N, Minami H, Su Y, Shaik MN, Zhang X, DiRienzo C, Zeremski M, Woolfsen A, Chan G, Talpaz M. Phase I/II trial of glasdegib in patients with primary or secondary myelofibrosis. Abstract No 7061; 2017 Jan. (J Clin Oncol; vol. 35, no. Sup). Mesa RA, Kiladjian J-J, Catalano JV, Devos T, Egyed M, Hellman A, McLornan D, Shimoda K, Winton EF, Deng W, Dubowy RL, Maltzman JD, Cervantes F, Gotlib JR. Phase 3 trial of momelotinib (MMB) vs ruxolitinib (RUX) in JAK inhibitor (JAKi) naive patients with myelofibrosis (MF). Abstr 7000; 2017 Jan. (J Clin Oncol; vol. 35, no. Sup). Huberty J, Eckert R, Gowin KL, Ginos BF, Kosiorek HE, Dueck AC, Larkey L, Mesa RA. Online yoga as a non-pharmacologic symptom management approach in myeloproliferative neoplasms. Abstr e21704; 2017 Jan. (J Clin Oncol; vol. 35, no. Sup). Allison Scotch, Robyn M. Scherber, Marlene Bruso, Heidi Elizabeth Kosiorek, Amylou C. Dueck, Holly Geyer, Veena D. S. Fauble, Alessandro M. Vannucchi, Ana Kerguelen Fuentes, Christen Lykkegaard Andersen, Elisabeth Ejerblad, Gunnar Birgegard, Peter L. Johansson, Bjorn Andreasson, David M Ross, Federico Sackman, Jean-Loup Demory, Constantine S. Tam, Jan J. Michiels, Deepti Radia, Joanne Ewing, Frances Wadelin, Robert N. Lown, Mary Frances McMullin, Wunna Swe, Jonathan O. Cullis, Nigel Sargant, Paul Moreton, Catherine Cargo, Mallika Sekhar, Satareh Shekouhi, and Ruben A Mesa. Myeloproliferative Neoplasm Quality of Life (MPN-QOL) Study Group: Results from the MPN Experimental Assessment of Symptoms By Utilizing Repetitive Evaluation (MEASURE) Trial; 2017 Jan. (Blood; vol. 130). Aaron T. Gerds, Tetsuzo Tauchi, Ellen K. Ritchie, Michael W. Deininger, Catriona HM Jamieson, Ruben Mesa, Mark Lawrence Heaney, Norio Komatsu, Hironobu Minami, M. Naveed Shaik, Xiaoxi Zhang, Christine DiRienzo, Mirjana Zeremski, Geoffrey Chan, and Moshe Talpaz. Phase I/II Trial of Glasdegib in Heavily Pre-Treated Patients with Primary or Secondary Myelofibrosis; 2017 Jan. (Blood; vol. 130). Alessandro Rambaldi, Alessandra Iurlo, Alessandro M. Vannucchi, Richard Noble, Nikolas von Bubnoff, Attilio Guarini, Andrzej Hellmann, Bruno Martino, Antonio Pezzutto, Giuseppe Carli, Marianna De Muro, Paolo Di Bartolomeo, Mary Frances Frances McMullin, Nathalie Cambier, Jean-Pierre Marolleau, Ruben A Mesa, Raoul Tibes, Paolo Bettica, Sara Manzoni, and Silvia DI Tollo. A Two-Part Study of Givinostat in Patients with Polycythemia Vera: The Maximum Tolerated Dose Selection and the Proof of Concept Final Results; 2017 Jan. (Blood; vol. 130). Jean-Jacques Kiladjian, Srdan Verstovsek, Martin Griesshammer, Tamas Masszi, Simon Durrant, Francesco Passamonti, Claire N. Harrison, Fabrizio Pane, Pierre Zachee, Keita Kirito, Carlos Besses, Masayuki Hino, Ana Ines Varela, Carole B. Miller, Elisa Rumi, Vittorio Rosti, Igor Wolfgang Blau, Ruben A Mesa, Tuochuan Dong, Nathalie Francillard, Mary Laughlin, and Alessandro M. Vannucchi. Results from the 208-Week (4-Year) Follow-up of RESPONSE Trial, a Phase 3 Study Comparing Ruxolitinib (Rux) with Best Available Therapy (BAT) for the Treatment of Polycythemia Vera (PV); 2017 Jan. (Blood; vol. 130). Raoul Tibes, Heidi Elizabeth Kosiorek, Amylou Dueck, Jeanne Palmer, James L. Slack, Emily Ann Knight, Saman Khalid Hashmi, James M. Bogenberger, Darci Zblewski, William J. Hogan, Mark R. Litzow, Ruben A Mesa, James M. Foran, Lisa Sproat, and Aref Al-Kali. Phase I/IB Study of Azacitidine and Hedgehog Pathway Inhibition with Sonidegib (LDE225) in Myeloid Malignancies; 2017 Jan. (Blood; vol. 130). Jeanne Palmer, Tania Jain, Katie L. Kunze, Daniel K. Partain, Nandita Khera, Lisa Sproat, Pierre Noel, James L. Slack, Vivek Roy, Jose F. Leis, William J. Hogan, Ayalew Tefferi, Veena D. S. Fauble, Mrinal M. Patnaik, Heidi Elizabeth Kosiorek, and Ruben A Mesa. Pre-Transplantation Predictors of Survival in Patients Undergoing Allogeneic Stem Cell Transplant for Myelofibrosis; 2017 Jan. (Blood; vol. 130). Eric Padron, Amy E. DeZern, Sandrine Niyongere, Markus Christian Ball, Maria Balasis, Hanadi Ramadan, Jeffrey E. Lancet, Alan F List, Ruben A Mesa, Gail J. Roboz, David P. Steensma, Mikkael A. Sekeres, and Rami S. Komrokji. Promising Results of a Phase 1/2 Clinical Trial of Ruxolitinib in Patients with Chronic Myelomonocytic Leukemia; 2017 Jan. (Blood; vol. 130). eslie Padrnos, Robyn M. Scherber, Blake T. Langlais, Amylou Dueck, Jennifer Huberty, Holly L. Geyer, Krisstina L. Gowin, Heidi Kosiorek, Marlene Bruso, Zhenya Senyak, Matthew M Clark, Michael Boxer, Mary Cotter, Claire N. Harrison, and Ruben A Mesa. Myeloproliferative Neoplasms and Depressive Symptoms, Diagnosis, and Associations; 2017 Jan. (Blood; vol. 130). Leslie Padrnos, Heidi Kosiorek, Robert M Bennett III, Amylou Constance Dueck, Krisstina L. Gowin, Robyn M. Scherber, Holly L. Geyer, Jeanne Palmer, Donald Northfelt, Joseph R Mikhael, Nandita Khera, and Ruben A Mesa. Duration Matters: Impact of Time from Diagnosis on Symptoms in Patients with Hematologic Malignancies; 2017 Jan. (Blood; vol. 130). Michael Richard Grunwald, Ivy Altomare, John M. Burke, Aaron T. Gerds, Mark A. Walshauser, Michael R. Savona, David J Kuter, Brady Lee Stein, Stephen Oh, Philomena Colucci, Ahmad B. Naim, Dilan Chamikara Paranagama, and Ruben A Mesa. Examining the Treatment Patterns and Blood Counts Among Patients with Polycythemia Vera Treated with Hydroxyurea in the United States: An Analysis from the Reveal Study; 2017 Jan. (Blood; vol. 130). Michael Richard Grunwald, John M. Burke, David J Kuter, Aaron T. Gerds, Brady Lee Stein, Michael R. Savona, Mark A. Walshauser, Ahmad B. Naim, Philomena Colucci, Dilan Chamikara Paranagama, and Ruben A Mesa. Patient-Reported Symptom Burden and Peripheral Blood Counts Among Patients with Polycythemia Vera: An Analysis from the Reveal Study; 2017 Jan. (Blood; vol. 130). Tania Jain, Katie L. Kunze, Daniel K. Partain, Heidi Kosiorek, Vivek Roy, Nandita Khera, James L. Slack, Mrinal M. Patnaik, William J. Hogan, Pierre Noel, Veena D. S. Fauble, Jose F. Leis, Lisa Sproat, Ruben A Mesa, and Jeanne Palmer. Transfusion Dependence at Day +100 Predicts Poorer Outcomes in Patients Undergoing Allogeneic Stem Cell Transplantation for Myelofibrosis; 2017 Jan. (Blood; vol. 130). Ryan P Topping, Michael W. Deininger, John Mascarenhas, Ruben A Mesa, Brady Lee Stein, Kevin L Obholz, Jason J Everly, and Srdan Verstovsek. Variance between Experts and Oncology Healthcare Providers in Managing Polycythemia Vera and Myelofibrosis: Analysis of an Online Treatment Decision Support Tool; 2017 Jan. (Blood; vol. 130). Amylou C. Dueck, Chad Gwaltney, Wen-Hung Chen, Lixia Wang, Renee Pierson, Jeremiah Trudeau, Sonya Eremenco, Stephen Joel Coons, and Ruben A Mesa. Quantitative Testing of the Myelofibrosis Symptom Assessment Form Version 4.0, a Harmonized Patient-Reported Outcome Measure for Collecting Key Secondary Endpoint Data in Myelofibrosis Clinical Trials; 2017 Jan. (Blood; vol. 130). Robyn M. Scherber, Blake T. Langlais, Holly Geyer, Amylou Dueck, Heidi Kosoriek, Carol Johnston, Leslie Padrnos, Jeanne Palmer, Angela G. Fleischman, and Ruben A Mesa. Nutrition and Supplement Use Characteristics in the Myeloproliferative Neoplasms: Results from the Nutrient Survey; 2017 Jan. (Blood; vol. 130). Krisstina L. Gowin, Blake T. Langlais, Heidi Elizabeth Kosiorek, Amylou Dueck, Denise Millstine, Jennifer Huberty, Ryan Eckert, Leslie Padrnos, Robyn M. Scherber, and Ruben A Mesa. Sleep and Psychiatric Disturbance in Chronic Philadelphia Negative Myeloproliferative Neoplasms; 2017 Jan. (Blood; vol. 130). Jingbo Yu, Dilan Chamikara Paranagama, Holly L. Geyer, Shreekant V. Parasuraman, and Ruben A. Mesa. Role of Symptom Burden in Disability Leave Among Patients with Myeloproliferative Neoplasms (MPNs): Findings from the Living with MPN Patient Survey; 2017 Jan. (Blood; vol. 130). Blake T. Langlais, Heidi Kosiorek, Holly Geyer, Robyn M. Scherber, Ruben A Mesa, and Amylou C. Dueck. Quality of Life and Symptom Burden Among Patients with Myeloproliferative Neoplasms: Do Symptoms Impact Quality of Life?; 2017 Jan. (Blood). Claire N. Harrison, Ruben A Mesa, Catriona Jamieson, John Hood, Julie Bykowski, Giulio Zuccoli, and James Brewer. Case Series of Potential Wernicke's Encephalopathy in Patients Treated with Fedratinib; 2017 Jan. (Blood; vol. 130). Geyer H, Kosiorek H, Dueck A, Slot S, Zweegman S, Kiladjian JJ, Boekhorst P, Schouten H, Sackmann F, Fuentes A, Hernandez-Maraver D, Pahl H, Stegelmann F, Doehner K, Bonatz K, Reiter A, Boyer F, Etienne G, Ianotto JC, Ranta D, Roy L, Cahn JY, Harrison C, Radia D, Muxi P, Maldonado N, Besses C, Cervantes F, Johansson P, Barosi G, Passamonti F, Andreasson B, Samuelsson J, Birgegard G, Sun X, Xu J, Zhang P, Xu Z, Barbui T, Barbui T, Senyak Z, Grieshammer M, Rambaldi A, Ferrari M, Lehmann T, Scherber R, Mesa R. Development of an mf patient reported outcome (pro) tool for fda qualification: comprehensive literature search and physician cognitive debriefing results; 2016 Jun. (Haematologica; vol. 101, no. S1). Geyer H, Kosiorek H, Dueck A, Slot S, Zweegman S, Mesa RA, Kiladjian J-J, et al. ReTHINK: A randomized, double-blind, placebo-controlled, multicenter, phase 3 study of ruxolitinib in early myelofibrosis patients; 2016 Jun. Harrison CN, Egyed M, Szoke A, Suvorov A, Perkins A, Mayer J, Ganly P, Schouten HC, Tosi P, Farber CM, Zachee P, Scheid C, Dean JP, Zhou H, Kiladjian J-J, Vannucchi AM, Nangalia J, Mead A, Mesa RA. Pacritinib (PAC) vs best available therapy (BAT) in myelofibrosis (MF): Outcomes in patients (pts) with baseline (BL) thrombocytopenia; 2016 Jun. Mesa RA, Egyed M, Szoke A, Suvorov A, Perkins A, Mayer J, Ganley P, Schouten HC, Tosi P, Farber CM, Zachee P, Scheid C, Dean JP, Granston T, Kiladjian J-J, Vannucchi AM, Nangalia J, Mead A, Harrison CN. Pacritinib (PAC) vs best available therapy (BAT) in myelofibrosis (MF): 60 week follow-up of the phase III PERSIST-1 trial; 2016 Jun. Gupta V, Verstovsek S, Mesa RA, Gotlib JR, DiPersio JF, Catalano JV, Deininger MWN, Brennan Miller C, Silver RT, Talpaz M, Winton EF, Huling Harvey J, Arcasoy MO, Hexner EO, Lyons RM, Paquette R, Raza A, Kornacki D, Sun K, Kantarjian HM, COMFORT-I Investigators. Long-term outcomes of ruxolitinib (RUX) therapy in patients (pts) with myelofibrosis (MF): 5-year update from COMFORT-I; 2016 Jun. Harrison CN, Egyed M, Szoke A, Suvorov A, Perkins A, Mayer J, Ganly P, Schouten HC, Tosi P, Farber CM, Zachee P, Scheid C, Dean JP, Zhou H, Kiladjian J-J, Vannucchi AM, Nangalia J, Mead A, Mesa RA. Outcomes in patients with myelofibrosis and RBC-transfusion dependence in the phase III PERSIST-1 study of pacritinib vs. best available therapy; 2016 Jun. Scherber R, Dueck A, Geyer H, Kosiorek H, Kiladjian JJ, Slot S, Zweegman S, Boekhorst P, Schouten H, Sackmann F, Fuentes A, Hernandez-Maraver D, Pahl H, Stegelmann F, Doehner K, Bonatz K, Reiter A, Boyer F, Etienne G, Ianotto JC, Ranta D, Roy L, Cahn JY, Harrison C, Radia D, Muxi P, Maldonado N, Besses C, Cervantes F, Johansson P, Barosi G, Vannucchi A, Passamonti F, Andreasson B, Samuelsson J, Birgegard G, Sun X, Xu J, Zhang P, Xu Z, Barbui T, Barbui T, Senyak Z, Grieshammer M, Rambaldi A, Ferrari M, Lehmann T, Mesa R. Symptoms, risk classification, and spleen size in jak2 inhibitor-naive myelofibrosis: implications for jak2 inhibitor treatment; 2016 Jun. (Haematologica; vol. 101, no. S1). Harrison C, Mead A, Panchal A, Fox S, Yap C, Houlton A, Aliman S, Wood M, Chen F, Coppell J, Panoskaltsis N, Scherber R, Geyer H, Dueck A, Mesa R, McMullin MF. Ruxolitinib compared with best available therapy for essential thrombocythaemia patients resistant or intolerant to hydroxycarbamide in majic - an investigator lead randomized trial; 2016 Jun. (Haematologica; vol. 101, no. S1). Huberty J, Eckert R, Gowin K, Dueck A, Mesa R. Online streaming yoga is a feasible non-pharmacologic management strategy in myeloproliferative neoplasm patients; 2016 Jun. (Haematologica; vol. 101, no. S1). Verstovsek S, Mesa RA, Gotlib JR, Gupta V, DiPersio JF, Catalano JV, Deininger MW, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH, Arcasoy MO, Hexner EO, Lyons RM, Paquette R, Raza A, Jones M, Kornacki D, Sun K, Kantarjian H. Long-term outcomes of ruxolitinib (rux) therapy in patients (pts) with myelofibrosis (mf): 5-year final efficacy and safety analysis from comfort-I; 2016 Jun. (Haematologica; vol. 101, no. S1). 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Relationship of JAK2 V617F allelic burden (AB) to demographics, disease characteristics, and response to therapy in Persist-1, a randomized phase III study of pacritinib (PAC) versus best available therapy (BAT) in patients (pts) with primary and seconda; 2016 Jan. (Blood; vol. 128). Palmer J, Kosiorek H, Fauble VDS, Geyer H, Dueck AC, Mesa R. Quality of life following allogeneic stem cell transplant for MF; 2016 Jan. (Blood; vol. 128). Moyo TK, Sochacki A, Ayers GD, Byrne MT, Strickland SA, Mohan SR, Harrison J, Berry LD, Dudley CV, Severs R, Dugger L, Miskin HP, Cavers A, Sportelli P, Michaelis LC, Mesa RA, Savona MR. Preliminary results from a phase I dose escalation trial of ruxolitinib and the PI3K delta inhibitor TGR-1202 in myelofibrosis; 2016 Jan. (Blood; vol. 128). Verstovesek S, Talpaz M, Ritchie EK, Wadleigh M, Odenike O, Jamieson C, Stein B, Rivera CE, Uno T, Mesa RA. Phase 1/2 study of NS-018, an oral JAK2 inhibitor, in patients with primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (postPV MF), or post-essential thrombocythemia myelofibrosis (postET MF); 2016 Jan. (Blood; vol. 128). Huberty J, Eckert R, Gowin KL, Ginos B, Kosiorek HE, Dueck AC, Mesa RA. Online-streamed yoga as a non-pharmacologic symptom management approach in myeloproliferative neoplasms; 2016 Jan. (Blood; vol. 128). Scotch AH, Scherber RM, Zhang N, Kosiorek HE, Dueck AC, Geyer H, Fauble V, Vannucchi AM, Kerguelen Fuentes A, Kykkegaard Andersen C, Ejerblad E, Birgegard G, Johansson PL, Andreasson B, Ross DM, Sackmann F, Demory J-L, Tam CS, Michiels JJ, Radia D, Mahalakshmi M, Jennings D, Ewing JC, Wadelin F, Lown RN, Drew V, Hudson J, McMullin MF, Swe W, Cullis JO, Sargant N, Moreton P, Kilner MF, Cargo C, Sekhar M, Shekouhi S, Mesa RA. 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Mesa RA, Hoffman R, Kosiorek HE, Prchal JT, Harrison CN, McMullin MF, Yacoub A, Rambaldi A, Berenzon D, VAnnucchi AM, Ewing JC, O`Connell CL, Kiladjian J-J, Mead A, Winton EF, Liebowtiz DS, DeStefano V, Arcasoy MO, Kessler CM, Catchatorian R, Rondelli D, Silver RT, Ritchie EK, Nagler A, Kremyanskaya M, Schlenk RF, Weinberg RS, Salama ME, Tognoni G, Prosperini G, DiLelio A, Serone E, Marfisi L, Orellana A, Barbui T, Dueck AC, Mascarenhas JO. Impact on MPN symptoms and quality of life of front line pegylated interferon alpha-2a vs. hydroxyurea in high risk polycythemia vera and essential thrombocythemia: interim analysis results of myeloproliferative disorders research consortium (MPD-Rc) 1; 2016 Jan. (Blood; vol. 128). Eckert R, Huberty J, Gowin KL, Ginos B, Kosiorek HE, Dueck AC, Mesa RA. Impact of weight on symptom burden outcomes in myeloproliferative neoplasm patients participating in an online yoga intervention; 2016 Jan. (Blood; vol. 128). Yu J, Parasuraman S, Paranagama D, Naim A, Dubinski D, Bai A, Mesa R. Impact of myeloproliferative neoplasms on patients` employment status and work productivity in the United States: results from living with MPN patient survey; 2016 Jan. (Blood; vol. 128). Rampal RK, Tamari R. Zhang N, McNamara CJ, Rapaport F, Litvin R, Maloy MA, Castro-Malaspina H, Giralt S, Weinberg RS, Mascarenhas J, Mesa RA, Rondelli D, Dueck AC, Levine RL, Gupta V, Hoffman R. Impact of genomic alterations on outcomes in myelofibrosis patients undergoing allogeneic hematopoietic stem cell transplantation; 2016 Jan. (Blood; vol. 128). Gupta V, Kosiorek HE, Klisovic RB, Galvin JP, Berenzon D, Yacoub A, Mesa RA, Tognoni G, Prosperini G, DiLelio A, Serone E, Marfisi L, Orellano A, Potiphar L, Salama ME, Weinberg RS, Dueck AC. Exploring the potential of JAK1/2 inhibitor ruxolitinib with reduced intensity hematopoietic cell transplantation (HCT) for myelofibrosis: stage I results of a prospective trial conducted through the myeloproliferative disorders - research consortium (MP; 2016 Jan. (Blood; vol. 128). Stein BL, Naim A, Grunwald MR, Moliterno AR, Oh ST, Paranagama D, Codaro JA, Sun H, Parasuraman S, Boccia RV, Mesa R. Examining the clinical features and underlying cardiovascular risk among patients with polycythemia vera in the REVEAL study; 2016 Jan. (Blood; vol. 128). Padrnos L, Bennett R, Kosiorek HE, Mikhael J, Dueck AC, Northfelt DW, Tibes R, Khera N, Mesa RA. Differences in cancer education between patients with hematologic malignancies and solid tumor malignancies: Lessons from a large multi-disease patient education symposium; 2016 Jan. (Blood; vol. 128). Jain T, Temkit M, Partain DK, Patnaik MM, Slack JL, Khera N, Hogan WJ, Roy V, Noel P, Leis JF, Sproat L, Fauble VDS, Mesa RA, Palmer J. Day 30 and day 100 CD33 chimerisms predict survival after allogeneic hematopoietic stem cell transplantation in patients with myelofibrosis; 2016 Jan. (Blood; vol. 128). Harrison CN, Mead A, Fox S, Panchal A, Yap C, Houlton AE, Aliman S, Ewing JC, Wood M, Chen F, Coppell J, Panoskaltsis N, Knapper S, Ali S, Hamblin A, Scherber RM, Geyer H, Scotch AH, Dueck AC, Cross NCP, Mesa RA, McMullin MF. Correlation between treatment outcomes, baseline characteristics and molecular responses in the Majic study which compared ruxolitinib to best available therapy in essential thrombocythemia; 2016 Jan. (Blood; vol. 128). 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Uno T, Verstovsek S, Mesa R, Talpaz M, Ritchie E, Wadleigh M, Odenike OM, Jamieson C, Stein B. Phase 1/2, dose-escalation study of oral ns-018 in patients with primary myelofibrosis (pmf), post-polycythemia vera mf (post-pv mf), or post-essential thrombocythemia mf (post-et mf); 2015 Jun. (Haematologica; vol. 100). Harrison C, Szoke A, Suvorov A, Egyed M, Prasad R, Mayer J, Jakucs J, Elinder A, Recher C, te Boekhorst PA, Knapper S, Somervaille T, Ciceri F, Quddus F, Straetmans N, Niederwieser D, Dean JP, Granston T, Kiladjian JJ, Vannucchi A, Nangalia J, Mead A, Mesa R. Persist-1: a phase iii study of pacritinib (pac) vs best available therapy (bat) in primary myelofibrosis (pmf), post-polycythemia vera mf (ppv-mf) or post-essential thrombocythemia mf (pet-mf); 2015 Jun. (Haematologica; vol. 100). Mesa R, Vannucchi A, Mead A, Wang L, Yang Y, Harrison C. Patient-reported outcomes (pros) in persist-1: a randomized, multi-country phase iii trial of the jak2 inhibitor pacritinib (pac) vs. best available therapy (bat) in myelofibrosis (mf); 2015 Jun. (Haematologica; vol. 100). Scherber R, Zhenya S, Geyer H, Dueck A, Clark M, Goldstein M, Kosiorek H, Boxer M, McCallister A, Cotter M, VanHusen B, Harrison C, Mesa R. Patient self-care interventions: do they impact mpn- related fatigue?; 2015 Jun. (Haematologica; vol. 100). Anderson L, Titmarsh G, McMullin MF, Duncombe A, Mesa R, Scherber R, Dueck A, DeVocht F, Fritschi L, Clarke M. Myeloproliferative neoplasm patients experience significant symptom burden; 2015 Jun. (Eur J Cancer Care; vol. 24). Padrnos L, Bennett R, Wu Q, Northfelt D, Mikhael J, Tibes R, Nagi Reddy S, Khera N, Mesa R. Knowledge assessment and educational intervention at a patient centered cancer symposium; 2015 Jun. (Haematologica; vol. 100). Gowin K, Dueck A, Mascarenhas J, Hoffman R, Reddy SN, Reeder C, Camoriano J, Fauble V, Tibes R, Gano K, Ghurye V, Koenig P, Mesa R. Interim analysis of a phase ii pilot trial of ruxolitinib combined with danazol for patients with myelofibrosis suffering from anemia; 2015 Jun. (Haematologica; vol. 100). Gowin KL, Verstovsek S, Daver NG, Pemmaraju N, Valdez R, Kosiorek H, Dueck AC, Mesa RA. Limitations of fibrosis grade as diagnostic criteria for post polycythemia vera and essential thrombocytosis myelofibrosis; 2015 May. (Clin Oncol; vol. 33, no. 15). Verstovsek S, Mesa RA, Martino B, Kiladjian JJ, Jones MM, He S, Habr D, Alecu I, Vannucchi AM. Ruxolitinib safety experience in the polycythemia vera clinical trial program; 2015 May. (J Clin Oncol; vol. 33, no. 15). Verstovsek S, Vannucchi AM, Griesshammer M, Masszi T, Durrant S, Passamonti F, Harrison CN, Pane F, Zachee P, Hino M, Moiraghi B, Miller CB, Rosti V, Mesa RA, Jones MM, Zhen HL, Li JJ, Francillard N, Habr D, Kiladjian JJ. Ruxolitinib in polycythemia vera: follow-up from the response trial; 2015 May. (J Clin Oncol; vol. 33, no. 15). Mesa RA, Egyed M, Szoke A, Suvorov A, Perkins A, Mayer J, Ganly P, Jourdan E, Schouten HC, Tosi P, Farber CM, Zachee P, Scheid C, Dean JP, Cernohous P, Nangalia J, Kiladjian JJ, Vannucchi AM, Mead A, Harrison CN. Results of the persist-1 phase iii study of pacritinib (pac) versus best available therapy (bat) in primary myelofibrosis (pmf), post-polycythemia vera myelofibrosis (ppv-mf), or post-essential thrombocythemia-myelofibrosis (pet-mf); 2015 May. (J Clin Oncol; vol. 33, no. 15). Scherber R, McMullin MF, Mead A, Fox S, Shah M, Abdi-Moradi S, Bell H, Doueck A, Aliman S, Green A, Wood M, Ewing J, Chen F, Coppell J, Knapper S, Yap C, Ahmed I, Geyer H, Mesa R, Harrison C. Baseline quality of life and symptom burden characteristics of patients intolerant to hydroxyurea: preliminary results from the majic trial; 2015 Apr. (Br J Haematol; vol. 169). Fauble V, Noel P, Mesa RA, Adams R, Leis J, Khera N, Sproat LO, Palmer J, Betcher J, Slack JL. Ruxolitinib prior to allogeneic stem cell transplant: the experience at Mayo Clinic Arizona; 2015 Feb. (Biol Blood Marrow Transplant; vol. 21, no. 2). Tibes R, Kosiorek HE, Dueck AC, Sproat L, Palmer J, Slack JL, Singh D, Gebhart E, Knight E, Hashmi SK, Wilcox RA, Bogenberger JM, Mesa RA, Al-Kali A. Phase I/IB Study of Azacitidine and Hedgehog Pathway Inhibition in Myeloid Malignancies; 2015 Jan. (Blood; vol. 126). Wehrle, J; Geer, T; Brudler, O; Schaefer, E; Tesch, H; Cavanna, D; Bachhuber, P; Markhauser, M; Koschmieder, S; Mesa, R A; Pahl, H L. Interim results of the phase IV JAKoMo trial, a prospective, non-interventional study of symptoms and quality of life in myelofibrosis patients receiving ruxolitinib therapy; 2015 Jan. (Oncology Research and Treatment; vol. 38, no. Sppl5). Kamal M, Boonstra PS, Weber AA, Perkins C, Gowin KL, Nguyen H, Mesa R, Gotlib JR, Talpaz M. A new prognostic model for response in myelofibrosis patients treated with jak2 inhibitors: a study from three US academic centers; 2014 Dec. (Blood; vol. 124, no. 21). Padrnos LJ, Wu Q, Scherber RM, Northfelt DW, Mikhael JR, Bennett RM, Dueck AC, Mesa R. Understanding and information in cancer patients: the impact of a cancer symposia on patient knowledge; 2014 Dec. (Blood; vol. 124, no. 21). Scherber RM, Senyak Z, Dueck AC, Clark M, Boxer M, McCallister A, Cotter M, VanHusen B, Harrison CN, Mesa R. The impact of medical comorbidities in mpn-related fatigue; 2014 Dec. (Blood; vol. 124, no. 21). Tibes R, Delman D, Hansen N, Gowin KL, Mesa R, Bogenberger JM. The hedgehog pathway as targetable vulnerability with 5-azacitidine in mds and aml; 2014 Dec. (Blood; vol. 124, no. 21). Mesa R, Vannucchi AM, Yacoub A, Zachee P, Garg M, Lyons R, Chedid S, Koschmieder S, Rinaldi C, Byrne J, Hasan Y, Passamonti F, Verstovsek S, Hunter D, Jones MM, He S, Morozov A, Martino B. The efficacy and safety of continued hydroxyurea therapy versus switching to ruxolitinib in patients with polycythemia vera: a randomized, double-blind, double-dummy, symptom study (relief); 2014 Dec. (Blood; vol. 124, no. 21). Gowin KL, Dueck AC, Verstovsek S, Daver N, Pemmaraju N, Valdez R, Mesa RA. The clinical phenotype of patients with primary myelofibrosis, polycythemia vera, and essential thrombocytosis whom only manifest who grade 1 fibrosis; 2014 Dec. (Blood; vol. 124, no. 21). Geyer HL, Scherber RM, Dueck AC, Kiladjian JJ, Xiao ZJ, Slot S, Zweegman S, Fuentes AK, Hernandez-Maraver D, Dohner K, Harrison CN, Radia DH, Muxi PJ, Sackman F, Besses C, Cervantes F, Johansson PL, Andreasson B, Rambaldi A, Barbui T, Vannucchi AM, Passamonti F, Samuelsson J, Birgegard G, Bonatz K, Reiter A, Boyer F, Etienne G, Ianotto JC, Ranta D, Roy L, Cahn JY, Maldonado NI, Barosi G, Ferrari M, Cannon K, te Boekhorst P, Schouten HC, Pahl HL, Griesshammer M, Stegelmann F, Lehmann T, Xu ZF, Zhang Y, Sun XJ, Xu JQ, Zhang PH, Mesa R. Symptom severity and clinical variables of polycythemia vera patients with splenomegaly, phlebotomy requirements and/or hydroxyurea use: a retrospective evaluation of 1334 patients; 2014 Dec. (Blood; vol. 124, no. 21). Verstovsek S, Kiladjian JJ, Mesa R, Jones MM, He S, Li JJ, Habr D, Vannucchi AM. Ruxolitinib efficacy by hematocrit control in patients with polycythemia vera: an analysis of the response trial; 2014 Dec. (Blood; vol. 124, no. 21). Miller CB, Komrokji RS, Mesa R, Sun W, Montgomery M, Verstovsek S. Practical measures of clinical benefit with ruxolitinib therapy: an exploratory analysis of comfort-i; 2014 Dec. (Blood; vol. 124, no. 21). Verstovsek S, Mesa RA, Foltz LM, Gupta V, Mascarenhas JO, Ritchie EK, Hoffman R, Silver RT, Kremyanskaya M, Pozdnyakova O, Hasserjian RP, Trehu E, Kantarjian HM, Gotlib JR. Phase 2 trial of prm-151, an anti-fibrotic agent, in patients with myelofibrosis: stage 1 results; 2014 Dec. (Blood; vol. 124, no. 21). Bogenberger JM, Hansen N, Delman D, Mesa RA, Tibes R. Mk2a substrate-selective p38 inhibitor cmpd1 selectively synergizes with hdac inhibitors in cd34( ) cells from myeloid malignancies; 2014 Dec. (Blood; vol. 124, no. 21). Gowin KL, Dueck AC, Mascarenhas JO, Hoffman R, Reeder CB, Camoriano J, Gano K, Ghurye V, Reddy SN, Koenig P, Fauble V, Tibes R, Mesa R. Interim analysis of a phase ii pilot trial of ruxolitinib combined with danazol for patients with primary myelofibrosis (mf), post essential thrombocythemia-myelofibrosis (post et), and post polycythemia vera myelofibrosis (pv mf) suffering from anemia; 2014 Dec. (Blood; vol. 124, no. 21). Mesa R, Miller CB, Thyne M, Mangan J, Goldberger S, Fazal S, Ma XM, Wilson W, Dubinski DG, Boyle J, Mascarenhas JO. Impact of myeloproliferative neoplasms (mpns) on patients' overall health and productivity: results from the mpn landmark survey in the United States; 2014 Dec. (Blood; vol. 124, no. 21). Scherber RM, Senyak Z, Dueck AC, Clark M, Boxer M, McCallister A, Cotter M, VanHusen B, Harrison CN, Mesa R. High prevalence of mood disorders in mpns and their possible role in mpn related fatigue; 2014 Dec. (Blood; vol. 124, no. 21). Mesa R, Miller CB, Thyne M, Mangan J, Goldberger S, Fazal S, Ma XM, Wilson W, Dubinski DG, Boyle J, Mascarenhas JO. Gaps in perception between patients and physicians regarding symptomatology and treatment attitudes for myeloproliferative neoplasms: mpn landmark survey; 2014 Dec. (Blood; vol. 124, no. 21). Singer J, Al-Fayoumi S, Ma HC, Komrokji RS, Mesa R, Verstovsek S. Comprehensive kinase profile of pacritinib, a non-myelosuppressive jak2 kinase inhibitor in phase 3 development in primary and post et/pv myelofibrosis; 2014 Dec. (Blood; vol. 124, no. 21). Kiladjian JJ, Vannucchi AM, Griesshammer M, Masszi T, Durrant S, Passamonti F, Harrison CN, Pane F, Zachee P, Mesa R, Jones MM, He S, Li JJ, Habr D, Verstovsek S. Clinical benefit of ruxolitinib treatment after crossover from best available therapy in patients with polycythemia vera: analysis of the response trial; 2014 Dec. (Blood; vol. 124, no. 221). Mesa R, Verstovsek S, Kiladjian JJ, Griesshammer M, Masszi T, Durrant S, Passamonti F, Harrison CN, Pane F, Zachee P, He S, Jones MM, Parasuraman S, Li JJ, Cote I, Habr D, Vannucchi AM. Changes in quality of life and disease-related symptoms in patients with polycythemia vera receiving ruxolitinib or best available therapy: response trial results; 2014 Dec. (Blood; vol. 124, no. 21). Verstovsek S, Talpaz M, Ritchie EK, Wadleigh M, Odenike O, Jamieson C, Stein BL, Tomonori U, Mesa R. A phase 1/2, open-label, dose-escalation, multi-center study to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of orally administered ns-018 in patients with primary myelofibrosis (pmf), post-polycythemia vera myelofibrosis (post; 2014 Dec. (Blood; vol. 124, no. 21). Tibes R, Delman D, Hansen N, Gowin KL, Mesa R, Bogenberger JM. The hedgehog pathway as a targetable vulnerability with 5-azacitidine in MDS and AML; 2014 Nov. (Blood). Tibes R, Chaudhuri L, Vincelette ND, Kohl BD, Naylor RM, Flatten KS, Peterson KL, McNally A, Gojo I, Karp JE, Mesa RA, Sproat LO, Bogenberger JM, Kaufmann SH. Chk1 and wee1 inhibition combine synergistically and represent a novel non-cytotoxic combination in acute myeloid leukemia; 2014 Sep. (Clin Lymphoma Myeloma Leuk; vol. 14). Gupta V, Mesa R, Deininger M, Rivera C, Sirhan S, Kawashima J, Shao L, Collins H, Verstovsek S. A phase i/ii, open-label study evaluating twice-daily administration of momelotinib (gs-0387, cyt387) in primary myelofibrosis or post-polycythemia vera or post-essential thrombocythemia myelofibrosis; 2014 Jun. (Haematologica; vol. 99). Verstovsek S, Kiladjian J-J, Griesshammer M, Masszi T, Durrant STS, Passamonti F, Harrison CN, Pane F, Zachee P, Mesa RA, He S, Jones M, Garrett WM, Li J, Pirron U, Lawniczek T, Vannucchi AM. Results of a prospective, randomized, open-label phase 3 study of ruxolitinib (RUX) in polycythemia vera (PV) patients resistant to or intolerant of hydroxyurea (HU): the RESPONSE trial; 2014 Jun. (J Clin Oncol; vol. 11). Verstovsek S, Mesa RA, Foltz LM, Gupta V, Mascarenhas J, Ritchie EK, Hoffman R, Silver RT, Hong W-J, Kremyanskaya M, Trehu EG, Kantarjian HM, Gotlib JR. Phase 2 trial of PRM-151, an antifibrotic agent, in patients with myelofibrosis: Stage 1 results; 2014 Jun. (J Clin Oncol; vol. 11). Sasaki K, Gotlib JR, Mesa RA, Ravandi F, Cortes JE, Kelly PF, Kutok JL, Kantarjian HM, Verstovsek S. A phase 2 study of IPI-926, an oral hedgehog inhibitor, in patients with myelofibrosis; 2014 Jun. (J Clin Oncol; vol. 11). Scherber R, Senyak Z, Dueck A, Clark M, Goldstein M, Boxer M, McCallister A, Cotter M, Harrison C, Mesa RA. The mpn fatigue project stage 2: understanding the role of comorbid conditions and fatigue-alleviating strategies in mpn fatigue; 2014 Jun. (Haematologica; vol. 99). Geyer H, Emanuel R, Dueck A, Alchaby H, Michaelis L, Kroger N, Giralt S, Guptas V, Popat U, Mesa R, Fauble V. Symptoms trial update: symptoms yielded in myelofibrosis patients after transplant as objectified by the mpn-saf tss; 2014 Jun. (Haematologica; vol. 99). Vannucchi AM, Kiladjian JJ, Griesshammer M, Masszi T, Durrant S, Passamonti F, Harrison CN, Pane F, Zachee P, Mesa R, He S, Jones MM, Garrett W, Li J, Francillard N, Habr D, Verstovsek S. Ruxolitinib proves superior to best available therapy in a prospective, randomized, phase 3 study (response) in patients with polycythemia vera resistant to or intolerant of hydroxyurea; 2014 Jun. (Haematologica; vol. 99). Begna K, Animesh P, Litzow M, Hanson C, Mesa R, Hogan W, Tefferi A. Pomalidomide in myelofibrosis: long term follow up and correlation with jak2v617f and calr mutations; 2014 Jun. (Haematologica; vol. 99). Verstovsek S, Mesa R, Foltz L, Gupta V, Mascarenhas J, Ritchie E, Hoffman R, Silver R, Hong WJ, Kremyanskaya M, Trehu E, Kantarjian H, Gotlib J. Phase 2 trial of prm-151, an anti-fibrotic agent, in patients with myelofibrosis: stage 1 results; 2014 Jun. (Haematologica; vol. 99). Geyer H, Emanuel R, Dueck A, Kiladjian JJ, Xiao Z, Slot S, Zweegman S, Sackman F, Fuentes AK, Hernandez-Maraver D, Dohner K, Harrison C, Radia D, Muxi P, Besses C, Cervantes F, Johansson P, Andreasson B, Rambaldi A, Barbui T, Vannucchi A, Passamonti F, Samuelsson J, Birgegard G, Bonatz K, Reiter A, Boyer F, Etienne G, Ianotto JC, Ranta D, Roy L, Cahn JY, Maldonado N, Barosi G, Ferrari M, Cannon K, te Boekhorst PA, Klauke K, Schouten H, Pahl H, Griesshammer M, Stegelmann F, Lehmann T, Xu Z, Zhang Y, Sun X, Xu J, Zhang P, Mesa R. Gender differences and mpn symptom burden: an analysis by the mpn quality of life international study group (mpn-qol isg); 2014 Jun. (Haematologica; vol. 99). Padrnos L, Wu Q, Scherber R, Robert B, Amylou D, Mesa R. Educational intervention in cancer patients: the impact of a cancer symposia on patient knowledge; 2014 Jun. (Haematologica; vol. 99). Scherber R, Dueck A, Knight E, Ross D, Geyer H, Vannucchi A, Fuentes AK, Andersen CL, Ejerblad E, Birgegard G, Johansson P, Andreasson B, Sackmann F, Demory JL, Constantine T, Michiels JJ, Radia D, Harrison C, Tefferi A, Mesa RA. An international assessment of standard medical therapy on symptom burden among mpn populations: preliminary findings of the measure trial; 2014 Jun. (Haematologica; vol. 99). Gowin K, Cherington C, Slack J, Tibes R, Sproat L, Mesa R. Allogeneic transplant outcomes in mpn blast phase; 2014 Jun. (Haematologica; vol. 99). Vekeman F, Huynh L, Sasane M, Cheng W, Duh MS, Paley C, Mesa R. Medical complications and resource utilization in blood transfusion-dependent patients with myelofibrosis by iron chelation therapy use; 2014 May. (Value Health; vol. 17, no. 3). Altriki M, Cheng MR, Fauble V, Khera N, Leis J, Mesa RA, Noel P, Slack JL, Tibes R, Sproat LO. Central nervous system leukemia in acute myeloid leukemia; 2014 Feb. (Biol Blood Marrow Transplant; vol. 20, no. 2). Dueck AC, Cleeland CS, Dantzer R, Sloan J, Verstovsek S, Emanuel RM, Geyer HL, Mesa RA. Cytokine Profile Changes in 309 Myelofibrosis Patients: Comparison of JAK1/JAK2 Inhibitor Therapy vs Placebo - Correlative Analysis from the COMFORT-I Trial. Abstract no. 14866; 2013 Nov. (Blood; vol. 122, no. 21). Hagop K, Kiladjian J-J, Gotlib J, Cervantes F, Mesa RA, Barosi G, Sarlis N, Peng W, Sandor VA, Sirulnik A, Hmissi A, Stalbovskaya V, Gupta V, Harrison CN, Verstovsek S. A Pooled Overall Survival Analysis of the COMFORT Studies: 2 Randomized Phase 3 Trials of Ruxolitinib for the Treatment of Myelofibrosis. ASH Abstract 14869; 2013 Oct. (Blood; vol. 122, no. 21). Senyak Z, McCallister A, Cotter M, VanHusen B, Harrison CN, Mesa RA. The MPN Fatigue Project: Stage 1 Results of the MPN Forum Internet-Based Survey Among 879 MPN Patients. ASH Abstract 14881; 2013 Oct. (Blood; vol. 122, no. 21). Mesa R, Cortes JE, Cervantes F, Milligan D, Masszi T, Mishchenko E, Jourdan E, Vannucchi AM, Drummond M, Jurgutis M, Kuliczkowski K, Gheorghita E, Passamonti F, Neumann F, Joulain F, Iqbal SU, Harrison CN. Symptom Burden and Health-Related Quality of Life (HRQoL) in Patients with Myelofibrosis (MF) Treated with Fedratinib (SAR302503) in a Phase III Study (JAKARTA). ASH Abstract 14865; 2013 Oct. (Blood; vol. 122, no. 21). Dueck, AC, Emanuel RM, Cannon K, Kiladjian J-J, Slot S, Zweegman S, Boekhorst P, Commandeur S, Schouten HC, Sackmann F, Fuentes AK, Hernandez D, Pahl HL, Griesshammer M, Stegelmann F, Döhner K, Lehmann T, Ranta D, Reiter A, Boyer F, Etienne G, Ianotto J-C, Roy L, Cahn J-Y, Harrison CN, Radia DH, Muxi PJ, Maldonado NI, Besses C, Cervantes F, Johansson P, Barbui T, Barosi G, Vannucchi AM, Passamonti F, Andreasson B, Ferrari M, Rambaldi A, Samuelsson J, Birgegard G, Xiao Z, Xu Z, Sun X, Xu J, Zhang P, Gale RPeter, Mesa RA. Sexuality Challenges, Intimacy, and MPN Symptom Burden: An Analysis By The MPN Quality Of Life International Study Group (MPN-QOL ISG). ASH Abstract 14876; 2013 Oct. (Blood; vol. 122, no. 21). Harrison CN, Cortes JE, Cervantes F, Mesa RA, Milligan D, Masszi T, Mishchenko E, Jourdan E, Vannucchi AM, Drummond M, Jurgutis M, Kuliczkowski K, Gheorghita E, Passamonti F, Neumann F, Gao G, Tefferi A. Results of a Randomized, Double-Blind, Placebo-Controlled Phase III Study (JAKARTA) of The JAK2-Selective Inhibitor Fedratinib (SAR302503) in Patients with Myelofibrosis (MF). ASH Abstract 14871; 2013 Oct. (Blood; vol. 122, no. 21). Mesa RA, Noel P, Adams R, Chang Y, Leis JF, Khera N, Sproat L, Reeder C, Klein J, Betcher JA, Higgins M, DeCook L, Palmer J, Gerber S, Henderson K, Beebe K, Chiffelle R, Olsen J, Toro A, Slack JL. Reduced Toxicity Conditioning with Fludarabine, BCNU, Melphalan and Anti-Thymocyte Globulin followed by Allogeneic Stem Cell Transplant for Patients with Primary and Post ET/PV Myelofibrosis: Single Center Experience at Mayo Clinic Arizona. ASH Abstract; 2013 Oct. (Blood; vol. 122, no. 21). Mesa RA, Salama ME, Giles JLK, Pitou C, Zimmermann AH, Price GL, Walgreen RA, Prchal J. Phase I Study of LY2784544, a JAK2 Selective Inhibitor, in Patients with Myelofibrosis (MF), Polycythemia Vera (PV), and Essential Thrombocythemia (ET). ASH Abstract 14875; 2013 Oct. (Blood; vol. 122, no. 21). Passamonti F, Barbui T, Barosi G, Begna K, Cazzola M, Cervantes F, Döhner K, Gisslinger H, Gupta V, Li W, Harrison CN, Kiladjian J-J, McMullin MF, Rambaldi A, Schiller GJ, Vannucchi AM, Mesa RA. Phase I Study of LY2784544, a JAK2 Selective Inhibitor, in Patients with Myelofibrosis (MF), Polycythemia Vera (PV), and Essential Thrombocythemia (ET). ASH Abstract 14875; 2013 Oct. (Blood; vol. 122, no. 21). Passamonti F, Barbui T, Barosi G, Begna K, Cazzola M, Cervantes F, Döhner K, Gisslinger H, Gupta V, Li W, Harrison CN, Kiladjian J-J, McMullin MF, Rambaldi A, Schiller GJ, Vannucchi AM, Mesa RA. Phase 3 Study of Pomalidomide in Myeloproliferative Neoplasm (MPN)-Associated Myelofibrosis with RBC-Transfusion-Dependence. ASH Abstract 14874; 2013 Oct. (Blood; vol. 122, no. 21). Rudd J, Chow D, Kassner M, Fauble V, Mesa RA, Yin H, Greene C, Tibes R. Pharmacological Validation of Potentiating Targets from SAHA RNA-Interference Modifier Screens in Acute Myeloid Leukemia. ASH Abstract 14883; 2013 Oct. (Blood; vol. 122, no. 21). Dean JP, Cernohous P, Komrokji RS, Seymour JF, Mesa RA, Campbell MS, Caldwell SE, Wang L, Myint Han. Pacritinib, a Dual JAK2/FLT3 Inhibitor: An Integrated Efficacy and Safety Analysis of Phase II Trial Data in Patients with Primary and Secondary Myelofibrosis (MF) and Platelet Counts ≤100,000/?l. ASH Abstract 14870; 2013 Oct. (Blood; vol. 122, no. 21). Mesa R, Komrokji RS, Sun W, Sandor VA, Verstovsek S. Optimizing Dose Titration of Ruxolitinib: the COMFORT-I Experience. ASH Abstract 14864; 2013 Oct. (Blood; vol. 122, no. 21). Emanuel RM, Geyer HL, Dueck AC, Kroeger N, Scott BL, Gerds AT, Popat UR, Giralt SA, Gupta V, Ross D, Knight E, Fuentes AK, Andersen CL, Ejerblad E, Birgegard G, Johansson P, Andreasson B, Sackmann F, Demory J-L, Tam CS, Michiels JJ, Radia DH, Boxer M, Mesa RA. Myeloproliferative Neoplasm Quality of Life (MPN-QOL) Study Group: Observational Study of Quality of Life and Symptomatic Response in Myelofibrosis Patients Receiving Undergoing Treatment with Conventional Therapy, the Measures Trial and Allogeneic Stem; 2013 Oct. (Blood; vol. 122, no. 21). Dueck AC, Geyer HL, Kiladjian J-J, Slot S, Zweegman S, Boekhorst P te, Commandeur S, Schouten HC, Sackmann F, Hernandez D, Fuentes AK, Pahl HL, Stegelmann F, Doehner K, Lehmann T, Bonatz K, Reiter A, Boyer F, Etienne G, Ianotto J-C, Ranta D, Roy L, Cahn J-Y, Harrison CN, Radia DH, Muxi PJ, Maldonado NI, Besses C, Cervantes F, Johansson P, Barbui T, Barosi G, Vannucchi AM, Passamonti F, Andreasson B, Ferrari M, Griesshammer M, Rambaldi A, Samuelsson J, Birgegard G, Xiao Z, Xu Z, Zhang Y, Sun X, Xu J, Zhang P, Gale RP, Tefferi A, Mesa RA. Myeloproliferative (MPN) Symptom Burden Response Thresholds: Assessment of MPN-SAF TSS Quartiles as Potential Markers of Symptom Response. ASH Abstract 14880; 2013 Oct. (Blood; vol. 122, no. 21). Vekeman F, Cheng WY, Sasane M, Huynh L, Kaminsky M, Duh MS, Paley C, Mesa R. Medical Complications in Patients with Myelofibrosis by Frequency of Blood Transfusion and Iron Chelation Therapy. ASH Abstract 14867; 2013 Oct. (Blood; vol. 122, no. 21). Verstovsek S, Mesa R, Gotlib J, Levy RS, Gupta V, Dipersio JF, Catalano JV, Deininger MW, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH, Arcasoy MO, Hexner E, Lyons RM, Paquette R, Raza A, Vaddi K, Sun W, Peng W, Sandor VA, Kantarjian HM. Long-Term Outcomes of Ruxolitinib Therapy in Patients with Myelofibrosis: 3-Year Update from COMFORT-I. ASH Abstract 14868; 2013 Oct. (Blood; vol. 122, no. 21). Dueck AC, Bennett RM, Emanuel RM, Mesa RA, Northfelt D, Mikhael JR, Glassley P, Stigge R, Aguirre A. Living with Cancer: Assessing the Educational, Symptomatic, and Quality of Life Impact of a Comprehensive Patient Symposia on Cancer Patients. ASH Abstract 14879; 2013 Oct. (Blood; vol. 122, no. 21). Dueck AC, Emanuel RM, Cannon K, Kiladjian J-J, Slot S, Zweegman S, Boekhorst P, Commandeur S, Schouten HC, Sackmann F, Fuentes AK, Hernandez-Maraver D, Pahl HL, Griesshammer M, Stegelmann F, Dohner K, Lehmann T, Bonatz K, Reiter A, Boyer F, Etienne G, Ianotto J-C, Ranta D, Roy L, Cahn J-Y, Harrison CN, Radia DH, Muxi PJ, Maldonado NI, Besses C, Cervantes F, Johansson P, Barbui T, Barosi G, Vannucchi AM, Passamonti F, Andreasson B, Ferrari M, Rambaldi A, Samuelsson J, Birgegard G, Xiao Z, Xu Z, Zhang Y, Sun X, Xu J, Zhang P, Peter G, Robert P, Mesa RA. Insomnia, Quality Of Life and MPN Symptom Burden: An Analysis By The MPN Quality Of Life International Study Group (MPN-QOL ISG); 2013 Oct. (Blood; vol. 122, no. 21). Schaap NPM, Zweegman S, Jourdan E, Kiladjian J-J, Cervantes F, Niederwieser D, Cortes JE, Passamonti F, Reiter A, Recher C, Döhner K, Heidel FH, Silver RT, Winton EF, Gupta V, Ojeda E, Gisslinger H, Vannucchi AM, Talpaz M, Zhang J, Shi W, Mesa RA. Insomnia, Quality Of Life and MPN Symptom Burden: An Analysis By The MPN Quality Of Life International Study Group (MPN-QOL ISG). ASH Abstract 14873; 2013 Oct. (Blood; vol. 122, no. 21). Schaap NPM, Zweegman S, Jourdan E, Kiladjian J-J, Cervantes F, Niederwieser D, Cortes JE, Passamonti F, Reiter A, Recher C, Döhner K, Heidel FH, Silver RT, Winton EF, Gupta V, Ojeda E, Gisslinger H, Vannucchi AM, Talpaz M, Zhang J, Shi W, Mesa RA. Efficacy and Safety of Fedratinib (SAR302503/TG101348) in Patients with Intermediate- or High-Risk Myelofibrosis (MF), Post-Polycythemia Vera (PV) MF, or Post-Essential Thrombocythemia (ET) MF Previously Treated with Ruxolitinib: Interim Results from a P; 2013 Oct. (Blood; vol. 122, no. 21). Issa J-P, Rizzieri D, Stock W, O'Connell C, Yee K, Tibes R, Griffiths EA, Walsh K, Feldman EJ, Ritchie E, Rao AV, Larson RA, Garcia-Manero G, Ravandi F, Jabbour E, Cortes JE, Schimmer A, Mesa RA, Blum W, Chung W, Naim S, Taverna P, Hao Y, Choy G, Azab M, Kantarjian HM. DNA Demethylation Activity Over Time and Safety of 3 Different Dose-Escalation Regimens of SGI-110, a Novel Subcutaneous (SQ) Hypomethylating Agent (HMA), in the Treatment of Relapsed/Refractory Patients with MDS and AML; 2013 Oct. (Blood; vol. 122, no. 21). Kornblau SM, Pierceall WE, Lena R, Qiu YH, Cardone M, Chaudhuri L, Fauble V, Elashoff M, Blake N, Mesa RA, Bogenberger JM. BH3 Profiling as Predictor of 5-Azacytidine and Decitabine Clinical Responses. ASH Abstract 14877; 2013 Oct. (Blood). Mehta J, Le-Ruyet O, Fryzek J, Iqbal SU, Mesa R. Epidemiology of primary myelofibrosis (pmf), essential thrombocythemia (et), and polycythemia vera (pv) in the European Union (EU); 2013 Sep. (Eur J Cancer; vol. 49). Yan M, Geyer H, Mesa R, Atallah E, Callum J, Bartoszko J, Wong F, Maganti M, Yee K, Gupta V. Clinical features of patients with Philadelphia-negative myeloproliferative neoplasms complicated by portal hypertension (P821); 2013 Jun. (Haematologica; vol. 98, no. s1). Radia DH, Perkins C, Claire HN, Mesa R, Gotlib J. Survey for the validation of modified MPN-symptom assessment form for patients with mast cell disorders (P815); 2013 Jun. (Haematologica; vol. 98, no. s1). Verstovsek S, Liang SY, Komrokji R, Mesa R, Seymour J, Dean JP, Wang L, Singer J, Myint H, Younes A. Safety overview of phase I-II studies of pacritinib, a non-myelosuppressive JAK2/LFT3 inhibitor, in patients with hematological malignancies (P278); 2013 Jun. (Haematologica; vol. 98, no. s1). Geyer H, Emanuel R, Fauble V, Dueck A, Knight E, Vannucchi A, Fuentes A, Andersen C, Ejerblad E, Birgegard G, Johansson P, Andreasson B, Ross D, Sackmann F, Demory JL, Tan C, Michiels JJ, Mesa R. Myeloproliferative neoplasm quality of life (MPN-QOL) study group: dual serial assessment studies for impact of standard therapeutic approaches in MPN populations (measure and symptoms trials) (P273); 2013 Jun. (Haematologica; vol. 98, no. s1). Emanuel R, Marchioli R, Dueck A, Geyer H, Finazzi G, Cavazzina R, Masciulli A, Scarano M, Vannucchi AM, Barbui T, Mesa RA. Impact of hematocrit on symptom burden among polycythemia vera patients (P276); 2013 Jun. (Haematologica; vol. 98, no. s1). Geyer H, Emanuel R, Dueck A, Kiladjian JJ, Slot S, Zweegman S, AW te Boekhorst P, Commandeur S, Schouten H, Sackmann F, Fuentes AK, Hernandez-Maraver D, Pahl H, Griesshammer M, Stegelmann F, Dohner K, Lehmann T, Bonatz K, Boyer F, Etienne G, Ianotto JC, Ranta D, Roy L, Cahn JY, Harrison C, Radia D, Muxi P, Moldonado N, Besses C, Cervantes F, Johansson P, Barbui T, Barosi G, Vannucchi A, Passamonti F, Andreasson B, Ferrari M, Rambaldi A, Samuelsson J, Birgegard G, Xiao Z, Xu Z, Zhang Y, Sun X, Xu J, Zhang P, Gale R, Mesa R. Do myeloproliferative neoplasms (MPNS) have stages? Analysis of relationship of disease duration prognostic scores, and symptomatic burden of 1467 MPN patients (P266); 2013 Jun. (Haematologica; vol. 98, no. s1).

  Book Chapter

  Mesa R. Myeloproliferative neoplasms: chronic myelogenous leukemia, polycythemia vera, essential thrombocythemia, and primary myelofibrosis. In: Tibes R, Mesa RA. Textbook of uncommon cancer. 5th Edition. Raghavan D; et al, editor. 2017. p. 816-829.

  Editorial

  Bogenberger JM, Delman D, Hansen N, Valdez R, Fauble V, Mesa RA, Tibes R. Ex vivo activity of BCL-2 family inhibitors ABT-199 and ABT-737 combined with 5-azacytidine in myeloid malignancies. Epub 2014 June 17 PMID:24707940 DOI:10.3109/10428194.2014.910657 Leuk Lymphoma 2015 Jan;56(1):226-229. Reilly JT, McMullin MF, Beer PA, Butt N, Conneally E, Duncombe AS, Green AR, Mikhaeel G, Gilleece MH, Knapper S, Mead AJ, Mesa RA, Sekhar M, Harrison CN. Use of jak inhibitors in the management of myelofibrosis: a revision of the british committee for standards in haematology guidelines for investigation and management of myelofibrosis 2012. PMID:24961987 Br J Haematol 2014 Nov;167(3):418-420. Mascarenhas J, Mesa R, Prchal J, Hoffman R. Optimal therapy for polycythemia vera and essential thrombocythemia can only be determined by the completion of randomized clinical trials Haematologica 2014 Jun;99(6):945-949. Geyer H, Cannon K, Knight E, Fauble V, Camoriano J, Emanuel R, Tibes R, Mesa R. Ruxolitinib in clinical practice for therapy of myelofibrosis: single USA center experience following Food and Drug Administration approval. Epub 2013 Jun 12 PMID:23647081 DOI:10.3109/10428194.2013.789507 Leuk Lymphoma 2014 Jan;55(1):195-197. Geyer H, Cannon K, Knight E, Fauble V, Camoriano J, Emanuel R, Tibes R, Mesa R. Ruxolitinib in clinical practice for therapy of myelofibrosis: single USA center experience following Food and Drug Administration approval. Epub 2013 Jun 12 PMID:23647081 DOI:10.3109/10428194.2013.789507 Leuk Lymphoma 2014 Jan;55(1):195-197.

  Electronic/Web Publication

  Mesa RA. Myelofibrosis: Trial Results from a Best of ASCO Abstract - Discussion of Phase III Study Findings on Momelotinib vs. Ruxolitinib in JAK Inhibitor - Naive Patients with Myelofibrosis 2017 Jun. Mesa RA. 2017 ASH Meeting on Hematologic Malignancies (MHM) 2017 May. Mesa RA. Myeloproliferative Neoplasms and Myelofibrosis: New Treatment Guidelines 2017 Mar. Mesa RA. Highlights from ASCO 2016 for Myeloproliferative Neoplasm 2016 Jun. Mesa RA. State of the Art in Myeloproliferative Diseases 2016 Jun. Mesa RA. Updates on PERSIST-1 Trial of Pacritinib for Myelofibrosis 2016 Jun. Henry DH, Mesa RA, Spivak J, Silver RT, Verstovsek S. MPN Updates Your Source for Myeloproliferative Neoplasm News 2016 Apr. 17 p. Mesa RA. What's Next for MPN? 2016 Apr. Mesa RA. Individualizing Care for MPN Patients 2016 Apr. Mesa RA. How to Manage MPN Patients 2016 Apr. Mesa RA. Update in Polycythemia Vera 2016 Mar. Mesa RA. MPN Research Updates from a Panel of Experts. http://www.patientpower.info/video/ash-coverage-mpn-research-updates-from-a-panel-of-experts/?autoplay=1 2015 Dec. Mesa RA. Heme Themes: Challenges in averting the progression of MPN, MDS 2015 Sep. Mesa RA. Ruxolitinib significantly improved symptom burden for patients with hydroxyurea-resistant PV.). http://www.healio.com/hematology-oncology/education-lab/mpn-central/interactive/mc-ash-mesa 2015 Jul. Mesa RA. PERSIST-1 phase III study of pacritinib versus BAT in PMF, PPV-MF, or PET-MF. http://oncology.tv/OncologyTVNetwork/TabId/1455/VideoId/1271/PERSIST1-Phase-III-Study-Of-Pacritinib-Versus-BAT-In-PMF-PPVMF-Or-PETMF.aspx 2015 Jul. Mesa RA. Highlights from ASCO 2015: Results from Phase 3 PERSIST-1 clinical trial. Available at: http://www.healio.com/hematology-oncology/education-lab/mpn-central/interactive/video-interviews?bclid=4106077613001 2015 Jul. Mesa RA. Gender Issues and MPN. Available at: http://www.healio.com/hematology-oncology/education-lab/mpn-central/interactive/video-interviews?bclid=4106077613001 2015 Jul. Helwick, C (Cited Mesa RA, Egyed M's abstract for this article). Helwick C (author): Pacritinib for Myelofibrosis: Effective in Patients with Thrombocytopenia; Reference: Mesa RA, Egyed M, Szoke A, et al: Results of the PERSIST-1 phase III study of pacritinib versus best available therapy in primary myelofibrosis, pos 2015 Jul. Mesa RA. PERSIST-1 Trial. http://l39gg632kcb0ewpfj-sites-default-files.s3.amazonaws.com/ASCO_2015/OE_ASCO_29_Mesa.mp4 2015 Jun. Mesa RA. Ruben A. Mesa, MD, Summarizes Results of the PERSIST-1 Study on Myelofibrosis. http://video.ascopost.com/conferences/2015-asco-annual-meeting/results-of-the-persist-1-study-on-myelofibrosis/ 2015 Jun. Mesa RA. Results of the PERSIST-1 Study on Myelofibrosis. http://video.ascopost.com/conferences/2015-asco-annual-meeting/results-of-the-persist-1-study-on-myelofibrosis-1/ 2015 Jun. Geyer HL, Mesa RA. Disease burden for the patient with myelofibrosis: Goals and response with therapy London, UK: Future Science Group; 2015 May. 19 p. Mesa RA. Staging and Diagnosing. CancerCare Teleconference: Progress in the Treatment of Polycythemia Vera (PV) 2015 May. Mesa RA. Overview of Polycythemia Vera (PV). CancerCare Teleconference: Progress in the Treatment of Polycythemia Vera (PV) 2015 May. Mesa RA. Current Standard of Care. CancerCare Teleconference: Progress in the Treatment of Polycythemia Vera (PV) 2015 May. Mesa RA. ASCO 2015 Interview (Chicago). http://live.promenade.hu/congressreport/videos/asco2015/may30/interview/ASCO-2015-Interview-Ruben-A-Mesa_x264.mp4 2015 May. Mesa RA. Novel JAK inhibitor pacritinib proving effective for easing symptoms of myelofibrosis. http://ecancer.org/video/3721/novel-jak-inhibitor-pacritinib-proving-effective-for-easing-symptoms-of-myelofibrosis.php 2015 May. Mesa RA. Ask the Expert: Polycythemia Vera. http://news.cancerconnect.com/have-a-question-about-polycythemia-vera-ask-the-expert/ 2015 Apr. Mesa RA. The Efficacy and Safety of Continued Hydroxyurea Therapy Versus Switching to Ruxolitinib in Patients with Polycythemia Vera. http://oncology.tv/OncologyTVNetwork/TabId/1455/VideoId/977/The-Efficacy-And-Safety-Of-Continued-Hydroxyurea-Therapy-Versus-Switc 2014 Dec. Mesa RA. ASH 2014 Coverage: JAK Inhibitor Approved for the Treatment of Polycythemia Vera (PV). http://www.patientpower.info/video/ash-coverage-jak-inhibitor-approved-for-the-treatment-of-polycythemia-vera-pv 2014 Dec. Mesa RA. Conozca los alimentos cancerigenos. http://univisionarizona.univision.com/salud/videos-de-salud/video/2014-12-15/conozca-los-alimentos-cancerigenos 2014 Dec. Mesa RA. Treatment of MPNs. http://learningcenter.ehaweb.org/eha/2012/interview/91401/ruben.mesa.treatment.of.mpns.html 2014 Dec. Geyer H, Mesa R. MPN Symptoms and Quality of Life 2014 Nov. Mesa RA. Your Quality-of-Life Concerns 2014 Nov. Mesa RA. Your Quality-of-Life Concerns 2014 Nov. Mesa RA. Overview of MPN 2014 Nov. Mesa R, Kiladjian JJ, Harrison C, Verstovsek S, Vannucchi A. Myeloproliferative Neoplasms (edited) 2014 Nov. Mesa R. Myelofibrosis Current Therapy and Management 2014 Nov. Mesa RA. Atypical Infections While Being Treated with a JAK Inhibitor (panel discussion) 2014 Sep. Mesa RA. How Gene Mutations are Affecting Diagnosis and Therapeutic Approaches in MDS and MPNs. http://www.patientpower.info/video/how-gene-mutations-are-affecting-diagnostic-and-therapeutic-approaches-in-mds-and-mpns 2014 Sep. Mesa RA. Loss of Response While Being Treated with a JAK Inhibitor (panel discussion) 2014 Sep. Mesa RA. EHA Quick Take: ENESTND 5-Year Follow-up 2014 Jun. Mesa RA. The New Frontier in Polycythemia Vera: A Fresh Look at Diagnosis, Prognosis, and Treatment. www.peervoice.com/pvr150 2014 May. Mesa RA. How Do MPNs Develop? http://goo.gl/ODQwFh 2014 Mar. Mesa RA. Understanding Why Myeloproliferative Neoplasms Develop. http://www.patientpower.info/video/understanding-why-myeloproliferative-neoplasms-develop 2014 Mar. Mesa RA. Living Stronger and Longer with MPNs 2014 Feb. Mesa RA. The Fatigue Project: Improving Quality of Life for MPN Patients. http://www.patientpower.info/video/the-fatigue-project-improving-quality-of-life-for-mpn-patients 2014 Feb. Mesa RA. MPN Research: It Takes a Village to Make a Difference. http://www.patientpower.info/video/mpn-research-it-takes-a-village-to-make-a-difference 2014 Jan. Mesa RA. Understanding the Evolving MPN Treatment Landscape 2013 Dec. Mesa RA. Overview of Polycythemia, Staging and Diagnosing, Current Standard of Care. CancerCare Teleconference, Q 2013 Dec. Mesa RA. Tratamientos prometedores para la mielofibrosis, ahora y en camino. https://vimeo.com/patientpower/review/78461603/4c15f217b4 2013 Nov. Mesa RA. Mayo Clinic to Open Stem Cell Research Lab. Available at: http://cronkitenewsonline.com/2013/09/mayo-clinic-opens-stem-cell-research-lab/ 2013 Sep. Mesa RA. Myelofibrosis: Key Prognostic Factors 2013 Aug. Mesa RA. Interactive broadcast about MPN 2013 Aug. Mesa RA. Should New MPN Medicines Be Covered by Insurance and Government Programs? http://www.patientpower.info/video/should-new-mpn-medicines-be-covered-by-insurance-and-government-programs?autoplay=1 2013 Jul. Mesa RA. What the Latest Research Studies Mean for Myelofibrosis Patients. http://www.patientpower.info/video/what-the-latest-research-studies-mean-for-myelofibrosis-patients 2013 Jul. Mesa RA. MPN Advocacy Report of the 18th Congress of the European Hematology Association in Regards to Myeloproliferative Neoplasms. http://mpnadvocacy.com/2013/06/dr-ruben-mesa-report-from-the-european-hematology-association/ 2013 Jun. Mesa RA. Communicating with Your Health Care Team, including Your Pharmacist 2013 Apr. Mesa RA. The Important Role of Adherence in the Management of CML 2013 Apr. Mesa RA. Overview of Current Treatments for Chronic Myelogenous Leukemia (CML) 2013 Apr. Mesa RA. Overview of Current Treatments for Chronic Myelogenous Leukemia (CML) 2013 Apr. Mesa RA. New Treatment Approaches and Clinical Trials 2013 Apr. Mesa RA. Dr. Mesa on the Mechanism of Action of Ruxolitinib in CML. http://www.targetedhc.com/targeted-communications/Dr-Mesa-on-the-Mechanism-of-Action-of-Ruxolitinib-in-CML 2013 Mar.

  Journal Article

  Palmer J, Scherber R, Girardo M, Geyer H, Kosiorek H, Dueck A, Jain T, Mesa R. Patient Perspectives Regarding Allogeneic Bone Marrow Transplantation in Myelofibrosis Biol Blood Marrow Transplant 2019 Feb;25(2):398-402. Gupta V, Kosiorek HE, Mead A, Klisovic RB, Galvin JP, Berenzon D, Yacoub A, Viswabandya A, Mesa RA, Goldberg J, Price L, Salama ME, Weinberg RS, Rampal R, Farnoud N, Dueck AC, Mascarenhas JO, Hoffman R. Ruxolitinib Therapy Followed by Reduced-Intensity Conditioning for Hematopoietic Cell Transplantation for Myelofibrosis: Myeloproliferative Disorders Research Consortium 114 Study Biol Blood Marrow Transplant 2019 Feb;25(2):256-264. Tamari R, Rapaport F, Zhang N, McNamara C, Kuykendall A, Sallman DA, Komrokji R, Arruda A, Najfeld V, Sandy L, Medina J, Litvin R, Famulare CA, Patel MA, Malloy M, Castro-Malaspina H, Giralt S, Weinberg RS, Mascarenhas JO, Mesa R, Rondelli D, Dueck AC, Levine RL, Gupta V, Hoffman R, Rampal RK. Impact of high molecular risk mutations on transplant outcomes in patients with myelofibrosis Biol Blood Marrow Transplant 2019 Jan;. Mazza GL, Kunze KL, Langlais BT, Kosiorek HE, DeWees TA, Geyer HL, Scherber RM, Mesa RA, Dueck AC. Item nonresponse on the Myeloproliferative Neoplasms Symptom Assessment Form (MPN-SAF): a comparison of missing data strategies Leuk Lymphoma 2019 Jan;. Yang M, Covington MF, Nguyen BD, Johnson GB, Mesa RA, Roarke MC. (99m)Tc-Sulfur Colloid Bone Marrow Scintigraphy in Diagnosis of Diffuse Pulmonary Extramedullary Hematopoiesis Secondary to Myelofibrosis J Nucl Med Technol 2018 Dec;46(4):368-372. Rampal RK, Mascarenhas JO, Kosiorek HE, Price L, Berenzon D, Hexner E, Abboud CN, Kremyanskaya M, Weinberg RS, Salama ME, Menghrajani K, Najfeld V, Sandy L, Heaney ML, Levine RL, Mesa RA, Dueck AC, Goldberg JD, Hoffman R. Safety and efficacy of combined ruxolitinib and decitabine in accelerated and blast-phase myeloproliferative neoplasms Blood Adv 2018 Dec;2(24):3572-3580. Scherber RM, Mesa RA. Managing myelofibrosis (MF) that "blasts" through: Advancements in the treatment of relapsed/refractor y and blast-phase MF Hematology Am Soc Hematol Educ Program 2018 Nov;2018(1):118-126. Huberty J, Eckert R, Larkey L, Gowin K, Mitchell J, Mesa R. Perceptions of Myeloproliferative Neoplasm Patients Participating in an Online Yoga Intervention: A Qualitative Study Integr Cancer Ther 2018 Oct;17(4):1150-1162. Gupta V, Kosiorek HE, Mead A, Klisovic RB, Galvin JP, Berenzon D, Yacoub A, Viswabandya A, Mesa RA, Goldberg J, Price L, Salama ME, Weinberg RS, Rampal R, Farnoud N, Dueck AC, Mascarenhas JO, Hoffman R. Ruxolitinib Therapy Followed by Reduced Intensity Conditioning for Hematopoietic Cell Transplantation for Myelofibrosis-Myeloproliferative Disorders Research Consortium 114 study. PMID: 30205231, doi: 10.1016/j.bbmt.2018.09.001. [Epub ahead of print] Biol Blood Marrow Transplant 2018 Sep;:30556-30561. Mesa RA. Refining the management of polycythemia vera Clin Adv Hematol Oncol 2018 Sep;16(9):587-589. Menghrajani K, Boonstra PS, Mercer JA, Perkins C, Gowin KL, Weber AA, Mesa R, Gotlib JR, Wang L, Singer JW, Talpaz M. Predictive models for splenic response to JAK-inhibitor therapy in patients with myelofibrosis Leuk Lymphoma 2018 Sep;. Mesa R, Boccia RV, Grunwald MR, Oh ST, Colucci P, Paranagama D, Parasuraman S, Stein BL. Patient-Reported Outcomes Data From REVEAL at the Time of Enrollment (Baseline): A Prospective Observational Study of Patients With Polycythemia Vera in the United States Clin Lymphoma Myeloma Leuk 2018 Sep;18(9):590-596. Mughal TI, Lion T, Abdel-Wahab O, Mesa R, Scherber RM, Perrotti D, Mauro M, Verstovsek S, Saglio G, Van Etten RA, Kralovics R. Precision immunotherapy, mutational landscape, and emerging tools to optimize clinical outcomes in patients with classical myeloproliferative neoplasms. doi: 10.1002/hon.2537. [Epub ahead of print] Review. PMID:30074634 Hematol Oncol 2018 Aug;. Grunwald MR, Stein BL, Boccia RV, Oh ST, Paranagama D, Parasuraman S, Colucci P, Mesa R. Clinical and Disease Characteristics From REVEAL at Time of Enrollment (Baseline): Prospective Observational Study of Patients With Polycythemia Vera in the United States Clin Lymphoma Myeloma Leuk 2018 Aug;. Langlais BT, Geyer H, Scherber R, Mesa RA, Dueck AC. Quality of life and symptom burden among myeloproliferative neoplasm patients: do symptoms impact quality of life? PMID: 30033837 Leuk Lymphoma 2018 Jul;22:1-7. Padrnos L, Bennett R, Kosiorek H, Dueck AC, Northfelt D, Mikhael J, Tibes R, Khera N, Mesa RA. Living with Cancer: an Educational Intervention in Cancer Patients Can Improve PatientReported Knowledge Deficit. doi: 10.1007/s1318701611231. PMID: 27730534 J Cancer Educ 2018 Jun;33(3):653-659. Yang M, Covington MF, Nguyen BD, Johnson GB, Mesa RA, Roarke MC. Tc-99m Sulfur Colloid Bone Marrow Scintigraphy in Diagnosis of Diffuse Pulmonary Extramedullary Hematopoesis Secondary to Myelofibrosis: Experience of a Tertiary Hospital. pii: jnmt.118.210534. doi: 10.2967/jnmt.118.210534. [Epub ahead of print] PMID:29 J Nucl Med Technol 2018 Jun;. Mesa RR, Monteiro T. Continuous Transitional Focus (CTF): A New Concept in Ophthalmic Surgery. doi: 10.1007/s40123-018-0134-x. [Epub ahead of print] Review. PMID:29915980 Ophthalmol Ther 2018 Jun;. Ma VT, Boonstra PS, Menghrajani K, Perkins C, Gowin KL, Mesa RA, Gotlib JR, Talpaz M. Treatment With JAK Inhibitors in Myelofibrosis Patients Nullifies the Prognostic Impact of Unfavorable Cytogenetics. doi: 10.1016/j.clml.2018.02.019. Epub 2018 Mar 2. PMID: 29574002 Clin Lymphoma Myeloma Leuk 2018 May;18(5):e201-e210. Jain T, Kunze KL, Temkit M, Partain DK, Patnaik MS, Slack JL, Khera N, Hogan WJ, Roy V, Noel P, Leis JF, Sproat LZ, Fauble V, Mesa RA, Palmer J. Comparison of reduced intensity conditioning regimens used in patients undergoing hematopoietic stem cell transplantation for myelofibrosis. . doi: 10.1038/s41409-018-0226-1. [Epub ahead of print] PMID:29795431 Bone Marrow Transplant 2018 May;. Barbui T, Tefferi A, Vannucchi AM, Passamonti F, Silver RT, Hoffman R, Verstovsek S, Mesa R, Kiladjian JJ, Hehlmann R, Reiter A, Cervantes F, Harrison C, Mc Mullin MF, Hasselbalch HC, Koschmieder S, Marchetti M, Bacigalupo A, Finazzi G, Kroeger N, Griesshammer M, Birgegard G, Barosi G. Philadelphia chromosomenegative classical myeloproliferative neoplasms: revised management recommendations from European LeukemiaNet. doi: 10.1038/s4137501800771. Epub 2018 Feb 27. Review. PMID: 29515238 Leukemia 2018 May;32(5):1057-1069. Mascarenhas J, Hoffman R, Talpaz M, Gerds AT, Stein B, Gupta V, Szoke A, Drummond M, Pristupa A, Granston T, Daly R, AlFayoumi S, Callahan JA, Singer JW, Gotlib J, Jamieson C, Harrison C, Mesa R, Verstovsek S. Pacritinib vs Best Available Therapy, Including Ruxolitinib, in Patients With Myelofibrosis: A Randomized Clinical Trial. doi: 10.1001/jamaoncol.2017.5818. PMID: 29522138 JAMA Oncol 2018 May;4(5):652-659. Yu J, Parasuraman S, Paranagama D, Bai A, Naim A, Dubinski D, Mesa R. Impact of Myeloproliferative neoplasms on patients` employment status and work productivity in the United States: results from the living with MPNs survey. doi: 10.1186/s1288501843229. PMID: 29653557 BMC Cancer 2018 Apr;18(1):420-420. Mughal TI, Gotlib J, Mesa R, Koschmieder S, Khoury HJ, Cortes JE, Barbui T, Hehlmann R, Mauro M, Saussele S, Radich JP, Van Etten RA, Saglio G, Verstovek S, Gale RP, Abdel-Wahab O. Recent advances in the genomics and therapy of BCR/ABL1-positive and -negative chronic myeloproliferative neoplasms. doi: 10.1016/j.leukres.2018.02.008. Epub 2018 Feb 14. Review. PMID:29466766 Leuk Res 2018 Apr;67:67-74. Mughal TI, Gotlib J, Mesa R, Koschmieder S, Khoury HJ, Cortes JE, Barbui T, Hehlmann R, Mauro M, Saussele S, Radich JP, Van Etten RA, Saglio G, Verstovek S, Gale RP, AbdelWahab O. Recent advances in the genomics and therapy of BCR/ABL1positive and negative chronic myeloproliferative neoplasms. doi: 10.1016/j.leukres.2018.02.008. Epub 2018 Feb 14. Review. PMID: 29466766 Leuk Res 2018 Apr;67:67-74. Jeanne Palmer, Marlene Bruso, Heidi Kosiorek, Amylou Dueck, Robyn Scherber, Holly Geyer, Tania Jain, Ruben Mesa. Views on Bone Marrow Transplant: A Survey of Patients with Myelofibrosis Biol Blood Marrow Transplantation 2018 Mar;24(3Sup):S325-S326. Eckert R, Huberty J, Gowin K, Mesa R, Marks L. Physical Activity as a Nonpharmacological Symptom Management Approach in Myeloproliferative Neoplasms: Recommendations for Future Research. doi: 10.1177/1534735416661417. Epub 2016 Jul 24. Review. PMID: 27458250 Integr Cancer Ther 2017 Dec;16(4):439-450. Pemmaraju N, Utengen A, Gupta V, Kiladjian JJ, Mesa R, Thompson MA. Rare Cancers and Social Media: Analysis of Twitter Metrics in the First 2 Years of a Rare-Disease Community for Myeloproliferative Neoplasms on Social Media-MPNSM. doi: 10.1007/s11899-017-0421-y. Review. PMID:29105027 Current Hematologic Malignancy Reports 2017 Dec;12(6):598-604. Mesa RA, Kiladjian JJ, Catalano JV, Devos T, Egyed M, Hellmann A, McLornan D, Shimoda K, Winton EF, Deng W, Dubowy RL, Maltzman JD, Cervantes F, Gotlib J. SIMPLIFY1: A Phase III Randomized Trial of Momelotinib Versus Ruxolitinib in Janus Kinase InhibitorNaive Patients With Myelofibrosis. doi: 10.1200/JCO.2017.73.4418. Epub 2017 Sep 20. PMID: 28930494 J Clin Oncol 2017 Dec;35(34):3844-3850. Scotch AH, Kosiorek H, Scherber R, Dueck AC, Slot S, Zweegman S, Boekhorst PAWT, Commandeur S, Schouten H, Sackmann F, Fuentes AK, HernandezMaraver D, Pahl HL, Griesshammer M, Stegelmann F, Dohner K, Lehmann T, Bonatz K, Reiter A, Boyer F, Etienne G, Ianotto JC, Ranta D, Roy L, Cahn JY, Harrison CN, Radia D, Muxi P, Maldonado N, Besses C, Cervantes F, Johansson PL, Barbui T, Barosi G, Vannucchi AM, Paoli C, Passamonti F, Andreasson B, Ferrari ML, Rambaldi A, Samuelsson J, Birgegard G, Xiao Z, Xu Z, Zhang Y, Sun X, Xu J, Kiladjian JJ, Zhang P, Gale RP, Mesa RA, Geyer HL. Symptom burden profile in myelofibrosis patients with thrombocytopenia: Lessons and unmet needs. doi: 10.1016/j.leukres.2017.10.002. Epub 2017 Oct 14. PMID: 29096334 Leuk Res 2017 Dec;63:34-40. Huang YL, Bryce AH, Culbertson T, Connor SL, Looker SA, Altman KM, Collins JG, Stellner W, McWilliams RR, Moreno-Aspitia A, Ailawadhi S, Mesa RA. Alternative Outpatient Chemotherapy Scheduling Method to Improve Patient Service Quality and Nurse Satisfaction. doi: 10.1200/JOP.2017.025510. Epub 2017 Dec 22. PMID: 29272201 J Oncol Pract 2017 Dec;14(2):e82-e91. Begna K, AlKali A, Elliott M, Foran J, Gangat N, Hogan W, Hook C, Leis J, Litzow M, Mesa R, Palmer J, Pardanani A, Patnaik M, Rivera C, Sproat L, Tibes R, WolanskyjSpinner A, Tefferi A. Current treatment preferences in chronic myeloid leukemia: The Mayo Clinic Physicians` survey. doi: 10.1002/ajh.24866. Epub 2017 Aug 17. No abstract available. PMID: 28730596 Am J Hematol 2017 Nov;92(11):E626-E627. Begna K, Al-Kali A, Elliott M, Foran J, Gangat N, Hogan W, Hook C, Leis J, Litzow M, Mesa R, Palmer J, Pardanani A, Patnaik M, Rivera C, Sproat L, Tibes R, Wolanskyj-Spinner A, Tefferi A. Current treatment preferences in chronic myeloid leukemia: The Mayo Clinic Physicians' survey. doi: 10.1002/ajh.24866. Epub 2017 Aug 17. No abstract available. PMID:28730596 Am J Hematol 2017 Nov;92(11):E626-E627. Mesa R, Harrison C. Authors` reply to comment What should be the endpoints of a symptomatic drug and its control? doi: 10.1016/S23523026( 17)301953. No abstract available. doi: 10.1016/S2352-3026(17)30195-3. No abstract available. PMID:29100557 Lancet Haematol 2017 Nov;4(11):e508-e509. Mesa RA. New guidelines from the NCCN for polycythemia vera. PMID: 29200417 Clin Adv Hematol Oncol 2017 Nov;15(11):848-850. Bogenberger J, Whatcott C, Hansen N, Delman D, Shi CX, Kim W, Haws H, Soh K, Lee YS, Peterson P, SiddiquiJain A, Weitman S, Stewart K, Bearss D, Mesa R, Warner S, Tibes R. Combined venetoclax and alvocidib in acute myeloid leukemia. doi: 10.18632/oncotarget.22284. eCollection 2017 Dec 5. doi: 10.18632/oncotarget.22284. eCollection 2017 Dec 5. PMID:29291023 Oncotarget 2017 Nov;8(63):107206-107222. Huberty J, Eckert R, Gowin K, Mitchell J, Dueck AC, Ginos BF, Larkey L, Mesa R. Feasibility study of online-streamed yoga for symptom management in patients with myeloproliferative neoplasms. Epub 2017 June 08 PMID:28596279 PMCID:PMC5622867 DOI:10.3324/haematol.2017.168583 Haematologica 2017 Oct;102(10):e384-e388. Huberty J, Eckert R, Gowin K, Mitchell J, Dueck AC, Ginos BF, Larkey L, Mesa R. Feasibility study of online yoga for symptom management in patients with myeloproliferative neoplasms. doi: 10.3324/haematol.2017.168583. Epub 2017 Jun 8. No abstract available. PMID: 28596279 Haematologica 2017 Oct;102(10):e384-e388. Verstovsek S, Mesa RA, Salama ME, Li L, Pitou C, Nunes FP, Price GL, Giles JL, D'Souza DN, Walgren RA, Prchal JT. A phase 1 study of the Janus kinase 2 (JAK2) inhibitor, gandotinib (LY2784544), in patients with primary myelofibrosis, polycythemia vera, and essential thrombocythemia. doi: 10.1016/j.leukres.2017.08.010. Epub 2017 Aug 31. PMID: 28934680 Leuk Res 2017 Oct;61:89-95. Mesa RA, Jamieson C, Bhatia R, Deininger MW, Fletcher CD, Gerds AT, Gojo I, Gotlib J, Gundabolu K, Hobbs G, McMahon B, Mohan SR, Oh S, Padron E, Papadantonakis N, Pancari P, Podoltsev N, Rampal R, Ranheim E, Reddy V, Rein LAM, Scott B, Snyder DS, Stein BL, Talpaz M, Verstovsek S, Wadleigh M, Wang ES, Bergman MA, Gregory KM, Sundar H. NCCN Guidelines Insights: Myeloproliferative Neoplasms, Version 2.2018. doi: 10.6004/jnccn.2017.0157. PMID: 28982745 J Natl Compr Canc Netw 2017 Oct;15(10):1193-1207. Verstovsek S, Gotlib J, Mesa RA, Vannucchi AM, Kiladjian JJ, Cervantes F, Harrison CN, Paquette R, Sun W, Naim A, Langmuir P, Dong T, Gopalakrishna P, Gupta V. Long-term survival in patients treated with ruxolitinib for myelofibrosis: COMFORTI and II pooled analyses. doi: 10.1186/s1304501705277. PMID: 28962635 J Hematol Oncol 2017 Sep;10(1):156-156. Verstovsek S, Gotlib J, Mesa RA, Vannucchi AM, Kiladjian JJ, Cervantes F, Harrison CN, Paquette R, Sun W, Naim A, Langmuir P, Dong T, Gopalakrishna P, Gupta V. Long-term survival in patients treated with ruxolitinib for myelofibrosis: COMFORT-I and -II pooled analyses. doi: 10.1186/s13045-017-0527-7. PMID:28962635 J Hematol Oncol 2017 Sep;10(1):156-156. Gwaltney C, Paty J, Kwitkowski VE, Mesa RA, Dueck AC, Papadopoulos EJ, Wang L, Feliciano J, Coons SJ. Development of a harmonized patientreported outcome questionnaire to assess myelofibrosis symptoms in clinical trials. doi: 10.1016/j.leukres.2017.05.012. Epub 2017 May 12. PMID: 28544906 Leuk Res 2017 Aug;59:26-31. Pemmaraju N, Thompson MA, Mesa RA, Desai T. Analysis of the Use and Impact of Twitter During American Society of Clinical Oncology Annual Meetings From 2011 to 2016: Focus on Advanced Metrics and User Trends. doi:10.1200/JOP.2017.021634. Epub 2017 May 17. PMID: 28514195 J Oncol Pract 2017 Jul;13(7):e623-e631. Harrison CN, Schaap N, Vannucchi AM, Kiladjian JJ, Tiu RV, Zachee P, Jourdan E, Winton E, Silver RT, Schouten HC, Passamonti F, Zweegman S, Talpaz M, Lager J, Shun Z, Mesa RA. Janus kinase2 inhibitor fedratinib in patients with myelofibrosis previously treated with ruxolitinib (JAKARTA2): a singlearm, openlabel, nonrandomised, phase 2, multicentre study. doi: 10.1016/S23523026(17)300881. Epub 2017 Jun 8. PMID: 28602585 Lancet Haematol 2017 Jul;4(7):e317-e324. Palmer J, Mesa R. Transplantation in Myelofibrosis Reaches the Molecular Age. doi: 10.1016/j.bbmt.2017.04.025. Epub 2017 May 2. No abstract available. PMID: 28476489 Biol Blood Marrow Transplant 2017 Jul;23(7):1043-1044. Ertz-Archambault N, Kosiorek H, Taylor GE, Kelemen K, Dueck A, Castro J, Marino R, Gauthier S, Finn L, Sproat LZ, Palmer J, Mesa RA, Al-Kali A, Foran J, Tibes R. Association of Therapy for Autoimmune Disease With Myelodysplastic Syndromes and Acute Myeloid Leukemia. doi: 10.1001/jamaoncol.2016.6435. PMID: 28152123 JAMA Oncol 2017 Jul;3(7):936-943. Scherber RM, Geyer HL, Dueck AC, Kosiorek HE, Finazzi G, Cavazzina R, Masciulli A, Scarano M, Vannucchi AM, Mesa RA, Barbui T. The potential role of hematocrit control on symptom burden among polycythemia vera patients: Insights from the CYTO-PV and MPN-SAF patient cohorts. Epub 2016 Nov 10 PMID:27830999 DOI:10.1080/10428194.2016.1246733 Leuk Lymphoma 2017 Jun;58(6):1481-1487. Scherber RM, Geyer HL, Dueck AC, Kosiorek HE, Finazzi G, Cavazzina R, Masciulli A, Scarano M, Vannucchi AM, Mesa RA, Barbui T. The potential role of hematocrit control on symptom burden among polycythemia vera patients: Insights from the CYTOPV and MPNSAF patient cohorts. doi: 10.1080/10428194.2016.1246733. Epub 2016 Nov 10. PMID: 27830999 Leuk Lymphoma 2017 Jun;58(6):1481-1487. Mesa RA. NCCN Debuts New Guidelines for Myeloproliferative Neoplasms. PMID:28515254 J Natl Compr Canc Netw 2017 May;15(5S):720-722. Mesa RA, Vannucchi AM, Mead A, Egyed M, Szoke A, Suvorov A, Jakucs J, Perkins A, Prasad R, Mayer J, Demeter J, Ganly P, Singer JW, Zhou H, Dean JP, Te Boekhorst PA, Nangalia J, Kiladjian JJ, Harrison CN. Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST1): an international, randomised, phase 3 trial. doi: 10.1016/S23523026(17)300273. Epub 2017 Mar 20. PMID: 28336242 Lancet Haematol 2017 May;4(5):e225-e236. Mesa RA, Vannucchi AM, Mead A, Egyed M, Szoke A, Suvorov A, Jakucs J, Perkins A, Prasad R, Mayer J, Demeter J, Ganly P, Singer JW, Zhou H, Dean JP, Te Boekhorst PA, Nangalia J, Kiladjian JJ, Harrison CN. Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST-1): an international, randomised, phase 3 trial. Epub 2017 Mar 20 PMID:28336242 DOI:10.1016/S2352-3026(17)30027-3 Lancet Haematol 2017 May;4(5):e225-e236. Tefferi A, Al-Ali HK, Barosi G, Devos T, Gisslinger H, Jiang Q, Kiladjian JJ, Mesa R, Passamonti F, Ribrag V, Schiller G, Vannucchi AM, Zhou D, Reiser D, Zhong J, Gale RP. A randomized study of pomalidomide vs placebo in persons with myeloproliferative neoplasm-associated myelofibrosis and RBC-transfusion dependence. Epub 2016 Oct 24 PMID:27773929 PMCID:5383927 DOI:10.1038/leu.2016.300 Leukemia 2017 Apr;31(4):896-902. Tefferi A, AlAli HK, Barosi G, Devos T, Gisslinger H, Jiang Q, Kiladjian JJ, Mesa R, Passamonti F, McMullin MF, Ribrag V, Schiller G, Vannucchi AM, Zhou D, Reiser D, Zhong J, Gale RP. A randomized study of pomalidomide vs placebo in persons with myeloproliferative neoplasmassociated myelofibrosis and RBCtransfusion dependence. doi: 10.1038/leu.2016.300. Epub 2016 Oct 24. Erratum in: Leukemia. 2017 May;31(5):1252. PMID: 27773929 Leukemia 2017 Apr;31(4):896-902. Verstovsek S, Savona MR, Mesa RA, Dong H, Maltzman JD, Sharma S, Silverman J, Oh ST, Gotlib J. A phase 2 study of simtuzumab in patients with primary, post-polycythaemia vera or post-essential thrombocythaemia myelofibrosis. Epub 2017 Feb 21 PMID:28220932 DOI:10.1111/bjh.14501 Br J Haematol 2017 Mar;176(6):939-949. Gowin K, Jain T, Kosiorek H, Tibes R, Camoriano J, Palmer J, Mesa R. Pegylated interferon alpha 2a is clinically effective and tolerable in myeloproliferative neoplasm patients treated off clinical trial. doi: 10.1016/j.leukres.2017.01.006. Epub 2017 Jan 5. PMID: 28113109 Leuk Res 2017 Mar;54:73-77. Verstovsek S, Savona MR, Mesa RA, Dong H, Maltzman JD, Sharma S, Silverman J, Oh ST, Gotlib J. A phase 2 study of simtuzumab in patients with primary, postpolycythaemia vera or postessential thrombocythaemia myelofibrosis. doi: 10.1111/bjh.14501. Epub 2017 Feb 21.PMID: 28220932 Br J Haematol 2017 Mar;176(6):939-949. Mesa RA. The new NCCN guidelines for the management of myelofibrosis. PMID:28398274 Leuk Res 2017 Mar;15(3):193-195. Gowin K, Jain T, Kosiorek H, Tibes R, Camoriano J, Palmer J, Mesa R. Pegylated interferon alpha - 2a is clinically effective and tolerable in myeloproliferative neoplasm patients treated off clinical trial. Epub 2017 Jan 05 PMID:28113109 DOI:10.1016/j.leukres.2017.01.006 Leuk Res 2017 Mar;54:73-77. Verstovsek S, Talpaz M, Ritchie E, Wadleigh M, Odenike O, Jamieson C, Stein B, Uno T, Mesa RA. A phase I, open-label, dose-escalation, multicenter study of the JAK2 inhibitor NS-018 in patients with myelofibrosis. Epub 2016 Aug 01 PMID:27479177 PMCID:5292677 DOI:10.1038/leu.2016.215 Leukemia 2017 Feb;31(2):393-402. Verstovsek S, Talpaz M, Ritchie E, Wadleigh M, Odenike O, Jamieson C, Stein B, Uno T, Mesa RA. A phase I, openlabel, doseescalation, multicenter study of the JAK2 inhibitor NS018 in patients with myelofibrosis. doi: 10.1038/leu.2016.215. Epub 2016 Aug 1. PMID: 27479177 Leukemia 2017 Feb;31(2):393-402. Mesa RA, Miller CB, Thyne M, Mangan J, Goldberger S, Fazal S, Ma X, Wilson W, Paranagama DC, Dubinski DG, Naim A, Parasuraman S, Boyle J, Mascarenhas JO. Differences in treatment goals and perception of symptom burden between patients with myeloproliferative neoplasms (MPNs) and hematologists/oncologists in the United States: Findings from the MPN Landmark survey. doi: 10.1002/cncr.30325. Epub 2016 Sep 30 Cancer 2017 Feb;123(3):449-458. Verstovsek S, Mesa RA, Gotlib J, Gupta V, DiPersio JF, Catalano JV, Deininger MW, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH Jr, Arcasoy MO, Hexner EO, Lyons RM, Paquette R, Raza A, Jones M, Kornacki D, Sun K, Kantarjian H; COMFORTI investigators. Long-term treatment with ruxolitinib for patients with myelofibrosis: 5 year update from the randomized, doubleblind, placebocontrolled, phase 3 COMFORT I trial. doi: 10.1186/s130450170417z. PMID: 28228106 J Hematol Oncol 2017 Feb;10(1):55-55. Verstovsek S, Mesa RA, Gotlib J, Gupta V, DiPersio JF, Catalano JV, Deininger MW, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH Jr, Arcasoy MO, Hexner EO, Lyons RM, Paquette R, Raza A, Jones M, Kornacki D, Sun K, Kantarjian H; COMFORT-I investigators. Long-term treatment with ruxolitinib for patients with myelofibrosis: 5-year update from the randomized, double-blind, placebo-controlled, phase 3 COMFORT-I trial. doi: 10.1186/s13045-017-0417-z. PMID:28228106 J Hematol Oncol 2017 Feb;10(1):55-55. Mesa RA. Highlights in myeloproliferative neoplasms from the 2016 American Society of Hematology meeting: Commentary. PMID: 28590458 Clin Adv Hematol Oncol 2017 Feb;Supp2(2):21-23. Mesa RA, Miller CB, Thyne M, Mangan J, Goldberger S, Fazal S, Ma X, Wilson W, Paranagama DC, Dubinski DG, Naim A, Parasuraman S, Boyle J, Mascarenhas JO. Differences in treatment goals and perception of symptom burden between patients with myeloproliferative neoplasms (MPNs) and hematologistsoncologists in the United States: Findings from the MPN Landmark survey. Epub 2016 Sept 30 PMID:27690182 PMCID:5 Cancer 2017 Feb;123(3):449-458. Robyn M. Scherber, Sarah Morse, Anais Leproux, Brianna M Craver, Hew Yeng Lai, Holly Geyer, Amylou C. Dueck, Jeanne Palmer, Leslie Padrnos, Ruben A Mesa, and Angela G. Fleischman. Needs and Preferences Regarding Nutrition and Supplement Use Among Individuals with Myeloproliferative Neoplasms: A Focus Group Study Blood 2017 Jan;130:5669-5669. Gupta V, Mesa RA, Deininger MW, Rivera CE, Sirhan S, Brachmann CB, Collins H, Kawashima J, Xin Y, Verstovsek S. A phase 1/2, open-label study evaluating twicedaily administration of momelotinib in myelofibrosis. doi: 10.3324/haematol.2016.148924. Epub 2016 Sep 15. PMID: 27634203 Haematologica 2017 Jan;102(1):94-102. Mesa R, Vannucchi AM, Yacoub A, Zachee P, Garg M, Lyons R, Koschmieder S, Rinaldi C, Byrne J, Hasan Y, Passamonti F, Verstovsek S, Hunter D, Jones MM, Zhen H, Habr D, Martino B. The efficacy and safety of continued hydroxycarbamide therapy versus switching to ruxolitinib in patients with polycythaemia vera: a randomized, doubleblind, doubledummy, symptom study (RELIEF). doi: 10.1111/bjh.14382. Epub 2016 Nov 8. PMID: 27858987 Br J Haematol 2017 Jan;176(1):76-85. Mesa R, Vannucchi AM, Yacoub A, Zachee P, Garg M, Lyons R, Koschmieder S, Rinaldi C, Byrne J, Hasan Y, Passamonti F, Verstovsek S, Hunter D, Jones MM, Zhen H, Habr D, Martino B. The efficacy and safety of continued hydroxycarbamide therapy versus switching to ruxolitinib in patients with polycythaemia vera: a randomized, double-blind, double-dummy, symptom study (RELIEF). Epub 2016 Nov 08 PMID:27858987 PMCID:5215488 DOI:10 Br J Haematol 2017 Jan;176(1):76-85. Koren-Michowitz M, Lavi N, Ellis MH, Vannucchi AM, Mesa R, Harrison CN. Management of extreme thrombocytosis in myeloproliferative neoplasms: an international physician survey. doi: 10.1007/s0027701628264. Epub 2016 Oct 13. PMID: 27734130 Ann Hematol 2017 Jan;96(1):87-92. Geyer HL, Kosiorek H, Dueck AC, Scherber R, Slot S, Zweegman S, te Boekhorst PAW, Senyak Z, Schouten HC, Sackmann F, Fuentes AK, Hernandez-Maraver D, Pahl HL, Griesshammer M, Stegelmann F, Dohner K, Lehmann T, Bonatz K, Reiter A, Boyer F, Etienne G, Ianotto JC, Ranta D, Roy L, Cahn JY, Harrison CN, Radia D, Muxi P, Maldonado N, Besses C, Cervantes F, Johansson PL, Barbui T, Barosi G, Vannucchi AM, Paoli C, Passamonti F, Andreasson B, Ferrari ML, Rambaldi A, Samuelsson J, Cannon K, Birgegard G, Xiao Z, Xu Z, Zhang Y, Sun X, Xu J, Kiladjian JJ, Zhang P, Gale RP, Mesa RA. Associations between gender, disease features and symptom burden in patients with myeloproliferative neoplasms: An analysis by the MPN QOL international working group. doi: 10.3324/haematol.2016.149559. Epub 2016 Aug 18. PMID: 27540137 Haematologica 2017 Jan;102(1):85-93. Gupta V, Mesa RA, Deininger MW, Rivera CE, Sirhan S, Brachmann CB, Collins H, Kawashima J, Xin Y, Verstovsek S. A phase 1/2, open-label study evaluating twice-daily administration of momelotinib in myelofibrosis. Epub 2016 Sept 15 PMID:27634203 PMCID:5210237 DOI:10.3324/haematol.2016.148924 Haematologica 2017 Jan;102(1):94-102. Abdulraheem Yacoub, John Mascarenhas, Heidi Elizabeth Kosiorek, Josef T. Prchal, Dmitriy Berenzon, Maria R. Baer, Ellen K Ritchie, Richard T Silver, Craig M. Kessler, Elliott F. Winton, Maria Chiara Finazzi, Alessandro Rambaldi, Alessandro M. Vannucchi, David S. Leibowitz, Damiano Rondelli, Murat O. Arcasoy, Rosalind Catchatourian, Joseph Vadakara, Vittorio Rosti, Elizabeth Hexner, Marina Kremyanskaya, Alicia Orellana, Lonette Sandy, Joseph Tripodi, Vesna Najfeld, Mohamed E. Salama, Rona Singer Weinberg, Raajit K. Rampal, Ruben A Mesa, Judith D Goldberg, Amylou C. Dueck, and Ronald Hoffman. Single-Arm Salvage Therapy with Pegylated Interferon Alfa-2a for Patients with High-Risk Polycythemia Vera or High-Risk Essential Thrombocythemia Who Are Either Hydroxyurea-Resistant or Intolerant: Final Results of the Myeloproliferative Disorders-Resear Blood 2017 Jan;130:321-321. Claire N. Harrison, Adam J. Mead, Anesh Panchal, Sonia Fox, Christina Yap, Emmanouela Gbandi, Aimee Houlton, Samah Alimam, Joanne Ewing, Marion Wood, Frederick Chen, Jason Coppell, Nicki Panoskaltsis, Steven Knapper, Sahra Ali, Angela Hamblin, Robyn Scherber, Amylou C. Dueck, Nicholas C. P. Cross, Ruben Mesa, and Mary Frances McMullin. Ruxolitinib vs best available therapy for ET intolerant or resistant to hydroxycarbamide. doi: https://doi.org/10.1182/blood-2017-05-785790 Blood 2017 Jan;130:1889-1897. Amylou C. Dueck, John Mascarenhas, Heidi Elizabeth Kosiorek, Abdulraheem Yacoub, Josef T. Prchal, Dmitriy Berenzon, Maria R. Baer, Ellen K Ritchie, Richard T Silver, Craig M. Kessler, Elliott F. Winton, Maria Chiara Finazzi, Alessandro Rambaldi, Alessandro M. Vannucchi, David S. Leibowitz, Damiano Rondelli, Murat O. Arcasoy, Rosalind Catchatourian, Joseph Vadakara, Vittorio Rosti, Elizabeth Hexner, Marina Kremyanskaya, Alicia Orellana, Lonette Sandy, Joseph Tripodi, Vesna Najfeld, Mohamed E. Salama, Rona Singer Weinberg, Raajit K. Rampal, Ronald Hoffman, and Ruben A Mesa. Single-Arm Phase II Trial of Pegylated Interferon Alpha 2a in Patients with High-Risk Essential Thrombocythemia or Polycythemia Vera Resistant or Intolerant to Hydroxyurea: MPN Symptom Impact & Quality of Life Results of the Myeloproliferative Disorders- Blood 2017 Jan;130:4206-4206. Robyn M. Scherber, Blake T. Langlais, Heidi Elizabeth Kosiorek, Amylou Dueck, Holly Geyer, Zhenya Senyak, Archie McCallister, Mary Cotter, Barbara VanHusen, Jeanne Palmer, Leslie Padrnos, Claire N. Harrison, Angela G. Fleischman, and Ruben A Mesa. Psychostimulant Use Among Myeloproloferative Neoplasm Patients Blood 2017 Jan;130:5657-5657. Ralph V. Boccia, Pedro M. Sanz-Altamira, Khuda Dad Khan, Dmitriy Berenzon, Ellen W. Friedman, Ahmad B. Naim, Dilan Chamikara Paranagama, and Ruben A Mesa. Examining the Frequency of Phlebotomy in Patients with Polycythemia Vera (PV) in the United States: An Analysis of Data from the REVEAL Study Blood 2017 Jan;130:5271-5271. Mesa R, Jamieson C, Bhatia R, Deininger MW, Gerds AT, Gojo I, Gotlib J, Gundabolu K, Hobbs G, Klisovic RB, Kropf P, Mohan SR, Oh S, Padron E, Podoltsev N, Pollyea DA, Rampal R, Rein LAM, Scott B, Snyder DS, Stein BL, Verstovsek S, Wadleigh M, Wang ES, Bergman MA, Gregory KM, Sundar H. Myeloproliferative neoplasms, version 2.2017 Journal of the National Comprehensive Cancer Network 2016 Dec;14(12):1572-1611. Pemmaraju N, Utengen A, Gupta V, Kiladjian JJ, Mesa R, Thompson MA. Social Media and Myeloproliferative Neoplasms (MPN): Analysis of Advanced Metrics From the First Year of a New Twitter Community: 2016 Dec;11(6):456-461. Padrnos LJ, Mesa RA, et al. Living with Cancer: An Educational Intervention in Cancer Patients Can Improve Patient Reported Knowledge Deficit. DOI: 10.1007/s13187-016-1123-1 J Cancer Education 2016 Nov;:1-7. Jain T, Mesa R. The development, safety and efficacy of pacritinib for the treatment of myelofibrosis. Epub 2016 Sept 21 PMID:27598824 DOI:10.1080/14737140.2016.1233061 Expert Rev Anticancer Ther 2016 Nov;16(11):1101-1108. Mesa RA, Komrokji RS, Verstovsek S. Ruxolitinib dose management as a key to long-term treatment success. Epub 2016 Aug 27 PMID:27567907 DOI:10.1007/s12185-016-2084-1 Haematologica 2016 Oct;104(4):420-429. Padrnos L, Bennett R, Kosiorek H, Dueck AC, Northfelt D, Mikhael J, Tibes R, Khera N, Mesa RA. Living with Cancer: an Educational Intervention in Cancer Patients Can Improve Patient-Reported Knowledge Deficit. [Epub ahead of print] PMID:27730534 DOI:10.1007/s13187-016-1123-1 J Cancer Education 2016 Oct;. Scherber RM, Mesa RA. Evaluating Elevated Hemoglobin-Reply. PMID:27623473 DOI:10.1001/jama.2016.11335 Blood 2016 Sep;316(10):1115-1115. Mesa R, Verstovsek S, Kiladjian JJ, Griesshammer M, Masszi T, Durrant S, Passamonti F, Harrison CN, Pane F, Zachee P, Zhen H, Jones MM, Parasuraman S, Li J, Cote I, Habr D, Vannucchi AM. Changes in quality of life and disease-related symptoms in patients with polycythemia vera receiving ruxolitinib or standard therapy. Epub 2016 Jan 03 PMID:26608702 DOI:10.1111/ejh.12707 Eur J Haematol 2016 Aug;97(2):192-200. Hinds DA, Barnholt KE, Mesa RA, Kiefer AK, Do CB, Eriksson N, Mountain JL, Francke U, Tung JY, Nguyen HM, Zhang H, Gojenola L, Zehnder JL, Gotlib J. Germ line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasms. Epub 2016 June 30 PMID:27365426 PMCID:5085254 DOI:10.1182/blood-2015-06-652941 Blood 2016 Aug;128(8):1121-1128. Mesa RA. Recent advances in the management of myelofibrosis. PMID:27487103 Clin Adv Hematol Oncol 2016 Aug;14(8):597-599. Mughal TI, Abdel-Wahab O, Rampal R, Mesa R, Koschmieder S, Levine R, Hehlmann R, Saglio G, Barbui T, Van Etten RA. Contemporary insights into the pathogenesis and treatment of chronic myeloproliferative neoplasms. Epub 2016 May 31 PMID:27240645 DOI:10.1080/10428194.2016.1185783 Leuk Lymphoma 2016 Jul;57(7):1517-1526. Mesa RA. Interviews with EMG Hematology Editorial Board EMJ Hematology 2016 Jul;:25-27. Verstovsek S, Vannucchi AM, Griesshammer M, Masszi T, Durrant S, Passamonti F, Harrison CN, Pane F, Zachee P, Kirito K, Besses C, Hino M, Moiraghi B, Miller CB, Cazzola M, Rosti V, Blau I, Mesa R, Jones MM, Zhen H, Li J, Francillard N, Habr D, Kiladjian JJ. Ruxolitinib versus best available therapy in patients with polycythemia vera: 80-week follow-up from the RESPONSE trial. Epub 2016 Apr 21 PMID:27102499 PMCID:5004461 DOI:10.3324/haematol.2016.143644 Haematologica 2016 Jul;101(7):821-829. Zahr AA, Salama ME, Carreau N, Tremblay D, Verstovsek S, Mesa R, Hoffman R, Mascarenhas J. Bone marrow fibrosis in myelofibrosis: pathogenesis, prognosis and targeted strategies. PMID:27252511 PMCID:5013940 DOI:10.3324/haematol.2015.141283 Haematologica 2016 Jun;101(6):660-671. Gowin K, Coakley M, Kosiorek H, Mesa R. Discrepancies of applying primary myelofibrosis prognostic scores for patients with post polycythemia veraessential thrombocytosis myelofibrosis. Epub 2016 June 27 PMID:27354022 PMCID:5046661 DOI:10.3324/haematol.2016.149013 Haematologica 2016 Jun;10(2016):e405-e406. Geyer HL, Andreasson B, Kosiorek HE, Dueck AC, Scherber RM, Martin KA, Butler KA, Harrison CN, Radia DH, Cervantes F, Kiladjian JJ, Reiter A, Birgegard G, Passamonti F, Senyak Z, Vannucchi AM, Paoli C, Xiao Z, Samuelsson J, Mesa RA. The role of sexuality symptoms in myeloproliferative neoplasm symptom burden and quality of life: An analysis by the MPN QOL International Study Group. Epub 2016 Apr 12 PMID:27070130 DOI:10.1002/cncr.30013 Cancer 2016 Jun;122(12):1888-1896. Verstovsek S, Atallah E, Mascarenhas J, Sun H, Montgomery M, Gupta V, Mesa R, Gotlib J. Efficacy of ruxolitinib on hepatomegaly in patients with myelofibrosis. Epub 2015 Nov 03 PMID:26526986 PMCID:4895165 DOI:10.1038/leu.2015.310 Leukemia 2016 Jun;30(6):1413-1415. Hobbs G, Mesa R. New drugs for myelofibrosis Expert Opinion on Orphan Drugs 2016 May;4(5):521-529. Scherber RM, Mesa RA. Elevated Hemoglobin or Hematocrit Level. PMID:27218633 DOI:10.1001/jama.2016.2435 JAMA 2016 May;315(20):2225-2226. Scherber RM, Kosiorek HE, Senyak Z, Dueck AC, Clark MM, Boxer MA, Geyer HL, McCallister A, Cotter M, Van Husen B, Harrison CN, Mesa RA. Comprehensively understanding fatigue in patients with myeloproliferative neoplasms. Epub 2015 Dec 15 PMID:26670597 DOI:10.1002/cncr.29753 Cancer 2016 Feb;122(3):477-485. Mesa R, Miller CB, Thyne M, Mangan J, Goldberger S, Fazal S, Ma X, Wilson W, Paranagama DC, Dubinski DG, Boyle J, Mascarenhas JO. Myeloproliferative neoplasms (MPNs) have a significant impact on patients' overall health and productivity: the MPN Landmark survey. PMID:26922064 PMCID:4769833 DOI:10.1186/s12885-016-2208-2 BMC Cancer 2016 Feb;16:167-167. Singer JW, Al-Fayoumi S, Ma H, Komrokji RS, Mesa R, Verstovsek S. Comprehensive kinase profile of pacritinib, a nonmyelosuppressive Janus kinase 2 inhibitor. Epub 2016 Aug 16 PMID:27574472 PMCID:4993559 DOI:10.2147/JEP.S110702 J Exp Pharmacol 2016 Jan;8:11-19. Geyer H, Scherber R, Kosiorek H, Dueck AC, Kiladjian JJ, Xiao Z, Slot S, Zweegman S, Sackmann F, Fuentes AK, Hernandez-Maraver D, Dohner K, Harrison CN, Radia D, Muxi P, Besses C, Cervantes F, Johansson PL, Andreasson B, Rambaldi A, Barbui T, Bonatz K, Reiter A, Boyer F, Etienne G, Ianotto JC, Ranta D, Roy L, Cahn JY, Maldonado N, Barosi G, Ferrari ML, Gale RP, Birgegard G, Xu Z, Zhang Y, Sun X, Xu J, Zhang P, te Boekhorst PA, Commandeur S, Schouten H, Pahl HL, Griesshammer M, Stegelmann F, Lehmann T, Senyak Z, Vannucchi AM, Passamonti F, Samuelsson J, Mesa RA. Symptomatic Profiles of Patients With Polycythemia Vera: Implications of Inadequately Controlled Disease. Epub 2015 Nov 23 PMID:26598745 DOI:10.1200/JCO.2015.62.9337 J Clin Oncol 2016 Jan;34(2):151-159. Mesa RA, Passamonti F. Individualizing Care for Patients With Myeloproliferative Neoplasms: Integrating Genetics, Evolving Therapies, and Patient-Specific Disease Burden. PMID:27249739 DOI:10.14694/EDBK_159322 Am Soc Clin Oncol Educ Book 2016 Jan;35:e324-e325. Mesa RA, Passamonti F. Individualizing Care for Patients With Myeloproliferative Neoplasms: Integrating Genetics, Evolving Therapies, and Patient-Specific Disease Burden. PMID:27249739 DOI:10.14694/EDBK_159322 Am Soc Clin Oncol Educ Book 2016 Jan;35:e324-e325. Leal AD, Thompson CA, Wang AH, Vierkant RA, Habermann TM, Ross JA, Mesa RA, Virnig BA, Cerhan JR. Hormonal and Reproductive Factors and Risk of Myeloproliferative Neoplasms in Postmenopausal Women. Epub 2015 Nov 12 PMID:26564251 PMCID:4713297 DOI:10.1158/1055-9965.EPI-15-0613 Cancer Epidemiol Biomarkers Prev 2016 Jan;25(1):151-157. Pemmaraju N, Gupta V, Mesa R, Thompson MA. Social Media and Myeloproliferative Neoplasms (MPN)--Focus on Twitter and the Development of a Disease-specific Community: Curr Hematol Malig Rep 2015 Dec;10(4):413-420. Pemmaraju N, Gupta V, Mesa R, Thompson MA. Social Media and Myeloproliferative Neoplasms (MPN)--Focus on Twitter and the Development of a Disease-specific Community: Curr Hematol Malig Rep 2015 Dec;10(4):413-420. Deeg HJ, Bredeson C, Farnia S, Ballen K, Gupta V, Mesa RA, Popat U, Hari P, Saber W, Seftel M, Tamari R, Petersdorf EW. Hematopoietic Cell Transplantation as Curative Therapy for Patients with Myelofibrosis: Long-Term Success in all Age Groups. Epub 2015 Sept 11 PMID:26371371 PMCID:4604067 DOI:10.1016/j.bbmt.2015.09.005 Biol Blood Marrow Transplant 2015 Nov;21(11):1883-1887. Eremenco S, Oko-Osi H, Arnold B, Savic L, Sterling K, Athearn R, Mesa RA. TRANSLATION AND LINGUISTIC VALIDATION OF THE MODIFIED MYELOPROLIFERATIVE NEOPLASM SYMPTOM ASSESSMENT FORM - TOTAL SYMPTOM SCORE (MMPN-SAF TSS) FOR USE IN 26 COUNTRIES. Epub 2015 Oct 20. PMID:26532644 DOI:10.1016/j.jval.2015.09.1252 Value Health 2015 Nov;18(7):A471-A472. Kroger NM, Deeg JH, Olavarria E, Niederwieser D, Bacigalupo A, Barbui T, Rambaldi A, Mesa R, Tefferi A, Griesshammer M, Gupta V, Harrison C, Alchalby H, Vannucchi AM, Cervantes F, Robin M, Ditschkowski M, Fauble V, McLornan D, Ballen K, Popat UR, Passamonti F, Rondelli D, Barosi G. Indication and management of allogeneic stem cell transplantation in primary myelofibrosis: a consensus process by an EBMTELN international working group. Epub 2015 Aug 21 PMID:26293647 DOI:10.1038/leu.2015.233 Leukemia 2015 Nov;29(11):2126-2133. Anderson LA, James G, Duncombe AS, Mesa R, Scherber R, Dueck AC, de Vocht F, Clarke M, McMullin MF. Myeloproliferative neoplasm patient symptom burden and quality of life: evidence of significant impairment compared to controls. Epub 2015 Sept 10 PMID:26113113 DOI:10.1002/ajh.24098 Am J Hematol 2015 Oct;90(10):864-870. Tibes R, Al-Kali A, Oliver GR, Delman DH, Hansen N, Bhagavatula K, Mohan J, Rakhshan F, Wood T, Foran JM, Mesa RA, Bogenberger JM. The Hedgehog pathway as targetable vulnerability with 5-azacytidine in myelodysplastic syndrome and acute myeloid leukemia. PMID:26483188 PMCID:4615363 DOI:10.1186/s13045-015-0211-8 J Hematol 2015 Oct;8:114-114. Anderson LA, James G, Duncombe AS, Mesa R, Scherber R, Dueck AC, de Vocht F, Clarke M, McMullin MF. Myeloproliferative neoplasm patient symptom burden and quality of life: evidence of significant impairment compared to controls. Epub 2015 Sept 10 PMID:26113113 DOI:10.1002/ajh.24098 Am J Hematol 2015 Oct;90(10):864-870. Mughal TI, Cross NC, Padron E, Tiu RV, Savona M, Malcovati L, Tibes R, Komrokji RS, Kiladjian JJ, Garcia-Manero G, Orazi A, Mesa R, Maciejewski JP, Fenaux P, Itzykson R, Mufti G, Solary E, List AF. An International MDSMPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplasticmyeloproliferative neoplasms. PMID:26341525 PMCID:4800699 DOI:10.3324/haematol.2014.114660 Haematologica 2015 Sep;100(9):1117-1130. Mughal TI, Cross NC, Padron E, Tiu RV, Savona M, Malcovati L, Tibes R, Komrokji RS, Kiladjian JJ, Garcia-Manero G, Orazi A, Mesa R, Maciejewski JP, Fenaux P, Itzykson R, Mufti G, Solary E, List AF. An International MDSMPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplasticmyeloproliferative neoplasms. PMID:26341525 PMCID:4800699 DOI:10.3324/haematol.2014.114660 Haematologica 2015 Sep;100(9):1117-1130. Pardanani A, Harrison C, Cortes JE, Cervantes F, Mesa RA, Milligan D, Masszi T, Mishchenko E, Jourdan E, Vannucchi AM, Drummond MW, Jurgutis M, Kuliczkowski K, Gheorghita E, Passamonti F, Neumann F, Patki A, Gao G, Tefferi A. Safety and Efficacy of Fedratinib in Patients With Primary or Secondary Myelofibrosis: A Randomized Clinical Trial. PMID:26181658 DOI:10.1001/jamaoncol.2015.1590 JAMA Oncol 2015 Aug;1(5):643-651. Gowin K, Verstovsek S, Daver N, Pemmaraju N, Valdez R, Kosiorek H, Dueck A, Mesa R. Limitations of fibrosis grade as diagnostic criteria for post polycythemia vera and essential thrombocytosis myelofibrosis. Epub 2015 Apr 17 PMID:25922307 DOI:10.1016/j.leukres.2015.04.004 Leuk Res 2015 Jul;39(7):684-688. Geyer HL, Mesa RA, Scherber RM. Reducing symptom burden in patients with myeloproliferative neoplasms in the era of JAK inhibitors. Epub 2015 Mar 17, PMID: 25644746 DOI: 10.3109/10428194.2014.983098 Leuk Lymphoma 2015 Jul;56(7):1989-1999. Mesa RA. New era of collaboration for MPN treatment. MPN Updates. Updates include all from 2004-2014 http://www.healio.com/hematology-oncology/education-lab/2014/02_february/mpn-updates/mpn-updates 2015 Jul;1(2):13-14. Mesa RA. Novel JAK Inhibitor Alleviates Key Myelofibrosis Symptoms Oncology & Biotech News 2015 Jul;9(6):41-42. Scherber R, Mesa RA. Survival and new cancers with myeloproliferative neoplasms. Epub 2015 June 11 PMID:26688382 DOI:10.1016/S2352-3026(15)00109-X Lancet Haematol 2015 Jul;2(7):272-273. Mesa RA, Scherber RM, Geyer HL. Reducing symptom burden in patients with myeloproliferative neoplasms in the era of Janus kinase inhibitors. Epub 2015 Mar 17 PMID:25644746 DOI:10.3109/10428194.2014.983098 Leuk Lymphoma 2015 Jul;07(2015):1989-1999. Sasaki K, Gotlib JR, Mesa RA, Newberry KJ, Ravandi F, Cortes JE, Kelly P, Kutok JL, Kantarjian HM, Verstovsek S. Phase ii evaluation of ipi-926, an oral hedgehog inhibitor, in patients with myelofibrosis. PMID:25641433 Leuk Lymphoma 2015 Jul;56(7):2092-2097. Mughal TI, Barbui T, Abdel-Wahab O, Kralovics R, Jamieson C, Kvasnicka HM, Mullaly A, Rampal R, Mesa R, Kiladjian JJ, Deininger M, Prchal J, Hehlmann R, Saglio G, Van Etten RA. Novel insights into the biology and treatment of chronic myeloproliferative neoplasms. Epub 2014 Nov 19, PMID: 25330439 PMCID: PMC5076856 DOI: 10.3109/10428194.2014.974594 Leuk Lymphoma 2015 Jul;56(7):1938-1948. Griesshammer M, Gisslinger H, Mesa R. Current and future treatment options for polycythemia vera. PMID:25832853 Ann Hematol 2015 Jun;94(6):901-910. Padrnos L, Dueck AC, Scherber R, Glassley P, Stigge R, Northfelt D, Mikhael J, Aguirre A, Bennett RM, Mesa RA. Quality of life and disease understanding: impact of attending a patient-centered cancer symposium. Epub 2015 Jan 30 PMID:25641947 PMCID:4472202 DOI:10.1002/cam4.422 Cancer Med 2015 Jun;4(6):800-807. Mesa RA, Verstovsek S, Gupta V, Mascarenhas JO, Atallah E, Burn T, Sun W, Sandor V, Gotlib J. Effects of ruxolitinib treatment on metabolic and nutritional parameters in patients with myelofibrosis from COMFORT-I. Epub 2014 Dec 27 PMID:25682576 PMCID:4418454 DOI:10.1016/j.clml.2014.12.008 Clin Lymphoma Myeloma Leuk 2015 Apr;15(4):214-221. Komrokji RS, Seymour JF, Roberts AW, Wadleigh M, To LB, Scherber R, Turba E, Dorr A, Zhu J, Wang L, Granston T, Campbell MS, Mesa RA. Results of a phase 2 study of pacritinib (SB1518), a JAK2JAK2(V617F) inhibitor, in patients with myelofibrosis. Epub 2015 Mar 11 PMID:25762180 PMCID:4490373 DOI:10.1182/blood-2013-02-484832 Blood 2015 Apr;125(17):2649-2655. Stein BL, Gotlib J, Arcasoy M, Nguyen MH, Shah N, Moliterno A, Jamieson C, Pollyea DA, Scott B, Wadleigh M, Levine R, Komrokji R, Klisovic R, Gundabolu K, Kropf P, Wetzler M, Oh ST, Ribeiro R, Paschal R, Mohan S, Podoltsev N, Prchal J, Talpaz M, Snyder D, Verstovsek S, Mesa RA. Historical views, conventional approaches, and evolving management strategies for myeloproliferative neoplasms. PMID:25870379 J Natl Compr Canc Netw 2015 Apr;13(4):424-434. Verstovsek S, Mesa RA, Gotlib J, Levy RS, Gupta V, DiPersio JF, Catalano JV, Deininger MW, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH Jr, Arcasoy MO, Hexner EO, Lyons RM, Raza A, Vaddi K, Sun W, Peng W, Sandor V, Kantarjian H, COMFORT-I investigators. Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I. Epub 2015 Jan 23 PMID:25616577 PMCID:4380721 DOI:10.3324/haematol.2014.115840 Haematologica 2015 Apr;100(4):479-488. Savona MR, Malcovati L, Komrokji R, Tiu RV, Mughal TI, Orazi A, Kiladjian JJ, Padron E, Solary E, Tibes R, Itzykson R, Cazzola M, Mesa R, Maciejewski J, Fenaux P, Garcia-Manero G, Gerds A, Sanz G, Niemeyer CM, Cervantes F, Germing U, Cross NC, List AF. MDS/MPN International Working Group. An international consortium proposal of uniform response criteria for myelodysplasticmyeloproliferative neoplasms (MDSMPN) in adults. Epub 2015 Jan 26 PMID:25624319 PMCID:4915792 DOI:10.1182/blood-2014-10-607341 Blood 2015 Mar;125(12):1857-1865. Barosi G, Tefferi A, Besses C, Birgegard G, Cervantes F, Finazzi G, Gisslinger H, Griesshammer M, Harrison C, Hehlmann R, Hermouet S, Kiladjian JJ, Kroger N, Mesa R, Mc Mullin MF, Pardanani A, Passamonti F, Samuelsson J, Vannucchi AM, Reiter A, Silver RT, Verstovsek S, Tognoni G, Barbui T. Clinical end points for drug treatment trials in BCR-ABL1-negative classic myeloproliferative neoplasms: consensus statements from European LeukemiaNET (ELN) and Internation Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT). Ep Leukemia 2015 Jan;29(1):20-26. Bogenberger JM, Delman D, Hansen N, Valdez R, Fauble V, Mesa RA, Tibes R. Ex vivo activity of BCL-2 family inhibitors ABT-199 and ABT-737 combined with 5-azacytidine in myeloid malignancies. Epub 2014 June 17 PMID:24707940 DOI:10.3109/10428194.2014.910657 Leuk Lymphoma 2015 Jan;56(1):226-229. Andersen CL, Siersma VD, Hasselbalch HC, Vestergaard H, Mesa R, Felding P, Olivarius ND, Bjerrum OW. Association of the blood eosinophil count with hematological malignancies and mortality. Epub 2015 Jan 16. PMID:25488524 DOI:10.1002/ajh.23916 Am J Hematol 2015 Jan;90(3):225-229. Vannucchi AM, Kiladjian JJ, Griesshammer M, Masszi T, Durrant S, Passamonti F, Harrison CN, Pane F, Zachee P, Mesa R, He S, Jones MM, Garrett W, Li J, Pirron U, Habr D, Verstovsek S. Ruxolitinib versus standard therapy for the treatment of polycythemia vera. PMID:25629741 PMCID:4358820 DOI:10.1056/NEJMoa1409002 N Engl J Med 2015 Jan;372(5):426-435. Vannucchi AM, Kiladjian JJ, Griesshammer M, Masszi T, Durrant S, Passamonti F, Harrison CN, Pane F, Zachee P, Mesa R, He S, Jones MM, Garrett W, Li J, Pirron U, Habr D, Verstovsek S. Ruxolitinib versus standard therapy for the treatment of polycythemia vera. PMID:25629741 PMCID:4358820 DOI:10.1056/NEJMoa1409002 N Engl J Med 2015 Jan;372(5):426-435. Cherington CC, Gowin KL, Mesa RA. Ruxolitinib for treatment of polycythemia vera Expert Opinion on Orphan Drugs 2015 Jan;3(9):1085-1096. Gowin KL, Mesa RA. Profile of pomalidomide and its potential in the treatment of myelofibrosis. Epub 2015 Apr 02 PMID:25897239 PMCID:4397931 DOI:10.2147/TCRM.S69211 Ther Clin Risk Manag 2015 Jan;11:549-556. Vekeman F, Cheng WY, Sasane M, Huynh L, Duh MS, Paley C, Mesa RA. Medical complications, resource utilization and costs in patients with myelofibrosis by frequency of blood transfusion and iron chelation therapy. Epub 2015 Mar 30 PMID:25676036 DOI:10.3109/10428194.2015.1016933 Leuk Lymphoma 2015 Jan;56(10):2803-2811. Geyer HL, Dueck AC, Scherber RM, Mesa RA. Impact of Inflammation on Myeloproliferative Neoplasm Symptom Development. 2015:284706, Epub 2015 Oct 11 PMID:26538823 PMCID:4619953 DOI:10.1155/2015/284706 Mediators Inflamm 2015 2015 Jan;2015(28470). Geyer HL, Mesa RA. Evidence for Janus kinase (JAK) inhibitors for the prevention of major morbid events in patients with myeloproliferative neoplasms (MPNs). PMID:26637784 DOI:10.1182/asheducation-2015.1.649 Hematology Am Soc Hematol Educ Program 2015 Jan;20(4):663-678. Geyer HL, Mesa RA. Emerging drugs for the treatment of myelofibrosis. Epub 2015 July 08 PMID:26153237 DOI:10.1517/14728214.2015.1061502 Clin Lymphoma Myeloma Leuk 2015 Jan;20(4):663-678. Yan M, Geyer H, Mesa R, Atallah E, Callum J, Bartoszko J, Yee K, Maganti M, Wong F, Gupta V. Clinical features of patients with Philadelphia-negative myeloproliferative neoplasms complicated by portal hypertension. Epub 2014 June 11 PMID:25027569 PMCID:4361182 DOI:10.1016/j.clml.2014.04.004 Leukemia 2015 Jan;:1-5. Scherber RM, Geyer HL, Mesa RA. Quality of life in MPN comes of age as a therapeutic target. PMID:25262210 DOI:10.1007/s11899-014-0239-9 Curr Hematol Malig Rep 2014 Dec;9(4):324-330. Geyer HL, Mesa RA. Therapy for myeloproliferative neoplasms: when, which agent, and how? Epub 2014 Nov 18 PMID:25696867 DOI:10.1182/asheducation-2014.1.277 Hematology Am Soc Hematol Educ Program 2014 Dec;2014(1):277-286. Geyer HL, Mesa RA. Therapy for myeloproliferative neoplasms: when, which agent, and how? PMID:25472969 DOI:10.1182/blood-2014-05-577635 Blood 2014 Dec;124(24):3529-3537. Mehta J, Wang H, Fryzek JP, Iqbal SU, Mesa R. Health resource utilization and cost associated with myeloproliferative neoplasms in a large United States health plan. Epub 2014 Feb 27. PMID:24450579 DOI:10.3109/10428194.2013.879127 Leuk Lymphoma 2014 Oct;55(10):2368-2374. Mesa RA. Letter to Our Readers. PMID:26568780 PMCID:4639939 Am Health Drug Benefits 2014 Oct;7(7Spl):S35-S35. Mascarenhas JO, Cross NC, Mesa RA. The future of JAK inhibition in myelofibrosis and beyond. Epub 2014 Jun 28. PMID:25043171 DOI:10.1016/j.blre.2014.06.002 Blood Rev 2014 Sep;28(5):189-196. Bogenberger JM, Kornblau SM, Pierceall WE, Lena R, Chow D, Shi CX, Mantei J, Ahmann G, Gonzales IM, Choudhary A, Valdez R, Camoriano J, Fauble V, Tiedemann RE, Qiu YH, Coombes KR, Cardone M, Braggio E, Yin H, Azorsa DO, Mesa RA, Stewart AK, Tibes R. BCL-2 family proteins as 5-Azacytidine-sensitizing targets and determinants of response in myeloid malignancies. Epub 2014 Jan 23 PMID:24451410 PMCID:4131248 DOI:10.1038/leu.2014.44 Leukemia 2014 Aug;28(8):1657-1665. Geyer H, Mesa RA. Assessing disease burden in patients with classic MPNs. Epub 2014 Jul 18. PMID:25189722 DOI:10.1016/j.beha.2014.07.006 Best Pract Res Clin Haematol 2014 Jun;27(2):107-119. Geyer HL, Scherber RM, Dueck AC, Kiladjian JJ, Xiao Z, Slot S, Zweegman S, Sackmann F, Fuentes AK, Hernandez-Maraver D, Dohner K, Harrison CN, Radia D, Muxi P, Besses C, Cervantes F, Johansson PL, Andreasson B, Rambaldi A, Barbui T, Vannucchi AM, Passamonti F, Samuelsson J, Birgegard G, Mesa RA. Distinct clustering of symptomatic burden among myeloproliferative neoplasm patients: retrospective assessment in 1470 patients. Epub 2014 Feb 19 PMID:24553173 PMCID:4067502 DOI:10.1182/blood-2013-09-527903 Blood 2014 Jun;123(24):3803-3810. Rosenthal A, Mesa RA. Janus kinase inhibitors for the treatment of myeloproliferative neoplasms. Epub 2014 Apr 25. PMID:24766055 DOI:10.1517/14656566.2014.913024 Expert Opin Pharmacother 2014 Jun;15(9):1265-1276. Titmarsh GJ, Duncombe AS, McMullin MF, O'Rorke M, Mesa R, De Vocht F, Horan S, Fritschi L, Clarke M, Anderson LA. How common are myeloproliferative neoplasms? A systematic review and meta-analysis. PMID:24971434 Am J Hematol 2014 Jun;89(6):581-587. Leal AD, Thompson CA, Wang AH, Vierkant RA, Habermann TM, Ross JA, Mesa RA, Virnig BA, Cerhan JR. Anthropometric, medical history and lifestyle risk factors for myeloproliferative neoplasms in the Iowa Women's Health Study cohort. Epub 2013 Oct 15 PMID:24114627 PMCID:3947165 DOI:10.1002/ijc.28492 Int J Cancer 2014 Apr;134(7):1741-1750. Tefferi A, Hudgens S, Mesa R, Gale RP, Verstovsek S, Passamonti F, Cervantes F, Rivera C, Tencer T, Khan ZM. Use of the Functional Assessment of Cancer Therapy--anemia in persons with myeloproliferative neoplasm-associated myelofibrosis and anemia. Epub 2014 Mar 14 PMID:24636526 DOI:10.1016/j.clinthera.2014.02.016 Clin Ther 2014 Apr;36(4):560-566. Chaudhuri L, Vincelette ND, Koh BD, Naylor RM, Flatten KS, Peterson KL, McNally A, Gojo I, Karp JE, Mesa RA, Sproat LO, Bogenberger JM, Kaufmann SH, Tibes R. CHK1 and WEE1 inhibition combine synergistically to enhance therapeutic efficacy in acute myeloid leukemia ex vivo. Epub 2013 Oct 31 PMID:24179152 PMCID:3971079 DOI:10.3324/haematol.2013.093187 Haematologica 2014 Apr;99(4):688-696. Mehta J, Wang H, Iqbal SU, Mesa R. Epidemiology of myeloproliferative neoplasms in the United States. Epub 2013 Jul 29. PMID:23768070 DOI:10.3109/10428194.2013.813500 Leuk Lymphoma 2014 Mar;55(3):595-600. Tibes R, Mesa RA. Targeting hedgehog signaling in myelofibrosis and other hematologic malignancies. PMID:24598114 PMCID:3975838 DOI:10.1186/1756-8722-7-18 J Hematol Oncol 2014 Mar;:7-18. Mesa RA. How I Manage Essential Thrombocythemia Clin Oncol News 2014 Mar;2014. Mesa RA, Kiladjian JJ, Verstovsek S, Al-Ali HK, Gotlib J, Gisslinger H, Levy R, Siulnik A, Gupta V, Khan M, DiPersio JF, McQuitty M, Catalano JV, Hunter DS, Knoops L, Deininger M, Cervantes F, Miller C, Vannucchi AM, Silver RT, Barbui T, Talpaz M, Barosi G, Winton EF, Mendeson E, Harvey JH Jr, Arcasoy MO, Hexner E, Lyons RM, Paquette R, Raza A, Sun W, Sandor V, Kantarjian HM, Harrison C. Comparison of placebo and best available therapy for the treatment of myelofibrosis in the phase 3 COMFORT studies. Epub 2013 Aug 02. PMID:23911705 PMCID:3912959 DOI:10.3324/haematol.2013.087650 Haematologica 2014 Feb;99(2):292-298. Padrnos L, Mesa RA. A closer look at pacritinib: A JAK2/FLT3 inhibitor for the treatment of myelofibrosis Expert Opinion on Orphan Drugs 2014 Jan;2(7):725-733. Vannucchi AM, Kiladjian JJ, Griesshammer M, Masszi T, Durrant S, Passamonti F, Harrison CN, Pane F, Zachee P, Mesa R, He S, Jones MM, Garrett W, Li J, Pirron U, Habr D, Verstovsek S. Ruxolitinib in polycythemia vera resistant to or intolerant of hydroxyurea N Engl J Med 2014 Jan;. Gowin K, Mesa R. Management of thrombocythemia. Epub 2014 Sept 29 PMID:25324966 PMCID:4197738 DOI:10.12688/f1000research.5361.1 F1000Res 2014 2014 Jan;3:227-227. Verstovsek S, Quintas-Cardama A, Kantarjian HM, Gotlib J, Gupta V, Atallah E, Mascarenhas J, Sun W, Sarlis NJ, Sandor V, Levy RS, Mesa RA. Management of cytopenias in patients with myelofibrosis treated with ruxolitinib and effect of dose modifications on efficacy outcomes Onco Targets and Therapy 2014 Jan;7:13-21. Moulard O, Mehta J, Fryzek J, Olivares R, Iqbal U, Mesa RA. Epidemiology of myelofibrosis, essential thrombocythemia, and polycythemia vera in the European Union. PMID:24372927 Eur J Haematol 2014 Jan;92(4):289-297. Verstovsek S, Mesa RA, Gotlib J, Levy RS, Gupta V, DiPersio JF, Catalano JV, Deininger MW, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH Jr, Arcasoy MO, Hexner EO, Lyons RM, Paquette R, Raza A, Vaddi K, Erickson-Viitanen S, Sun W, Sandor V, Kantarjian HM. Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I. Epub 2013 Sep 13. PMID:24038026 PMCID:3856961 DOI:10.3324/haematol.2013.092155 Haematologica 2013 Dec;98(12):1865-1871. Gowin K, Emanuel R, Geyer H, Mesa RA. The new landscape of therapy for myelofibrosis. PMID:24101258 DOI:10.1007/s11899-013-0178-x Curr Hematol Malig Rep 2013 Dec;8(4):325-332. Kantarjian HM, Silver RT, Komrokji RS, Mesa RA, Tacke R, Harrison CN. Ruxolitinib for myelofibrosis--an update of its clinical effects. Epub 2013 Oct 02. PMID:24238036 DOI:10.1016/j.clml.2013.09.006 Clin Lymphoma Myeloma Leuk 2013 Dec;13(6):638-645. Gowin K, Mesa R. Emerging therapies for the treatment of chronic Philadelphia chromosome-negative myeloproliferative neoplasm-associated myelofibrosis. Epub 2013 Sep 25. PMID:24066969 DOI:10.1517/13543784.2013.832199 Expert Opin Investig Drugs 2013 Dec;22(12):1603-1611. Mesa RA. Clearing the path for MPN therapy monitoring. PMID:24288406 DOI:10.1182/blood-2013-10-529990 Blood 2013 Nov;122(23):3704-3705. Mesa R. Management of cytopenias in patients with myelofibrosis treated with ruxolitinib and effect of dose modifications on efficacy outcomes. Epub 2013 Dec 17 PMID:24368888 PMCID:3869911 DOI:10.2147/OTT.S53348 Onco Targets Ther 2013 Oct;7:13-21. Harrison C, Mesa R, Ross D, Mead A, Keohane C, Gotlib J, Verstovsek S. Practical management of patients with myelofibrosis receiving ruxolitinib. Epub 2013 Oct 02. PMID:24083419 DOI:10.1586/17474086.2013.827413 Expert Rev Hematol 2013 Oct;6(5):511-523. Abelsson J, Andreasson B, Samuelsson J, Hultcrantz M, Ejerblad E, Johansson B, Emanuel R, Mesa R, Johansson P. Patients with polycythemia vera have worst impairment of quality of life among patients with newly diagnosed myeloproliferative neoplasms. Epub 2013 Jul 29. PMID:23398206 DOI:10.3109/10428194.2013.766732 Leuk Lymphoma 2013 Oct;54(10):2226-2230. Tibes R, Mesa RA. Emerging drugs for polycythemia vera. PMID:23968379 DOI:10.1517/14728214.2013.832754 Expert Opin Emerg Drugs 2013 Sep;18(3):393-404. Mesa RA, Silver RT, Verstovsek S, Mascarenhas J, Kessler CM, Rondelli D, Goldberg JD, Marchioli R, Demakos EP, Silverman LR, Hoffman R. Single agent bevacizumab for myelofibrosis: results of the Myeloproliferative Disorders Research Consortium Trial. Epub 2013 June 28 PMID:23812932 PMCID:3762099 DOI:10.3324/haematol.2012.083337 Haematologica 2013 Sep;98(9):1421-1423. DeAngelo DJ, Mesa RA, Fiskus W, Tefferi A, Paley C, Wadleigh M, Ritchie EK, Snyder DS, Begna K, Ganguly S, Ondovik MS, Rine J, Bhalla KN. Phase II trial of panobinostat, an oral pan-deacetylase inhibitor in patients with primary myelofibrosis, post-essential thrombocythaemia, and post-polycythaemia vera myelofibrosis. Epub 2013 May 23. PMID:23701016 DOI:10.1111/bjh.12384 Br J Haematol 2013 Aug;162(3):326-335. Tefferi A, Cervantes F, Mesa R, Passamonti F, Verstovsek S, Vannucchi AM, Gotlib J, Dupriez B, Pardanani A, Harrison C, Hoffman R, Gisslinger H, Kroger N, Thiele J, Barbui T, Barosi G. Revised response criteria for myelofibrosis: International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) and European LeukemiaNet (ELN) consensus report. Epub 2013 July 09 PMID:23838352 PMCID:4828070 DOI:10.1182/blood-2 Blood 2013 Aug;122(8):1395-1398. Mesa RA, Shields A, Hare T, Erickson-Viitanen S, Sun W, Sarlis NJ, Sandor V, Levy RS, Verstovsek S. Progressive burden of myelofibrosis in untreated patients: assessment of patient-reported outcomes in patients randomized to placebo in the COMFORT-I study. Epub 2013 May 17 PMID:23684482 DOI:10.1016/j.leukres.2013.04.017 Leuk Res 2013 Aug;37(8):911-916. Harrison CN, Mesa RA, Kiladjian JJ, Al-Ali HK, Gisslinger H, Knoops L, Squier M, Sirulnik A, Mendelson E, Zhou X, Copley-Merriman C, Hunter DS, Levy RS, Cervantes F, Passamonti F, Barbui T, Barosi G, Vannucchi AM. Health-related quality of life and symptoms in patients with myelofibrosis treated with ruxolitinib versus best available therapy. Epub 2013 May 14. PMID:23672349 DOI:10.1111/bjh.12375 Br J Haematol 2013 Jul;162(2):229-239. Mesa RA. Improving disease burden in myelofibrosis: changing the natural history of the disease. PMID:23977768 Oncology (Williston Park) 2013 Jul;27(7):715-716. Cherington C, Schuster SR, Kundranda M, Valdez R, Mesa RA, Northfelt DW. A surprising cause of masses in the chest. Epub 2012 Oct 17. PMID:23076627 DOI:10.1002/ajh.23343 Am J Hematol 2013 Jun;88(6):518-521. Barosi G, Mesa R, Finazzi G, Harrison C, Kiladjian JJ, Lengfelder E, McMullin MF, Passamonti F, Vannucchi AM, Besses C, Gisslinger H, Samuelsson J, Verstovsek S, Hoffman R, Pardanani A, Cervantes F, Tefferi A, Barbui T. Revised response criteria for polycythemia vera and essential thrombocythemia: an ELN and IWG-MRT consensus project. Epub 2013 Apr 16. PMID:23591792 PMCID:3674675 DOI:10.1182/blood-2013-01-478891 Blood 2013 Jun;121(23):4778-4781. Verstovsek S, Mesa RA, Gotlib J, Levy RS, Gupta V, DiPersio JF, Catalano JV, Deininger M, Miller C, Silver RT, Talpaz M, Winton EF, Harvey JH Jr, Arcasoy MO, Hexner E, Lyons RM, Paquette R, Raza A, Vaddi K, Erickson-Viitanen S, Sun W, Sandor V, Kantarjian HM. The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo-controlled, Phase III study in patients with myelofibrosis. Epub 2013 Mar 11. PMID:23480528 DOI:10.1111/bjh.12274 Br J Haematol 2013 May;161(4):508-516. Mesa RA, Gotlib J, Gupta V, Catalano JV, Deininger MW, Shields AL, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH, Hare T, Erickson-Viitanen S, Sun W, Sandor V, Levy RS, Kantarjian HM, Verstovsek S. Effect of ruxolitinib therapy on myelofibrosis-related symptoms and other patient-reported outcomes in COMFORT-I: a randomized, double-blind, placebo-controlled trial. Epub 2013 Feb 19 PMID:23423753 PMCID:4979167 DOI:10.1200/JCO.2012.44.4489 J Clin Oncol 2013 Apr;31(10):1285-1292. Hensley B, Geyer H, Mesa R. Polycythemia vera: current pharmacotherapy and future directions. PMID:23480062 DOI:10.1517/14656566.2013.779671 Expert Opin Pharmacother 2013 Apr;14(5):609-617. Noel P, Mesa RA. Eosinophilic myeloid neoplasms. PMID:23385615 DOI:10.1097/MOH.0b013e32835d81bf Leuk Lymphoma 2013 Mar;20(2):157-162. Emanuel RM, Geyer HL, Mesa RA. Ruxolitinib as an emerging treatment in myelofibrosis. DOI:10.2147/BLCTT.S24926 Dovepress Journal 2013 Mar;2013(3):11-18.

  Other

  Mesa RA. Cancer Stats. Interview with Chad Hartman Available at: http://minnesota.cbslocal.com/audio/1384-the-chad-hartman-show/2-4-14-chad-hartman-show-1p-cancer-stats/ WCCO-AM News Radio 2014 Feb;. Mesa RA. Mayo Clinic Stem Cell Lab. http://www.azpbs.org/arizonahorizon/detail.php?id=2244 2013 Sep;.

  Review Article

  Jain T, Mesa RA, Palmer JM. Allogeneic Stem Cell Transplantation in Myelofibrosis. doi: 10.1016/j.bbmt.2017.05.007. Epub 2017 May 10. Review. PMID: 28499938 Biol Blood Marrow Transplant 2017 Sep;23(9):1429-1436. Padrnos L, Mesa RA. Myeloproliferative Neoplasms: Translating New Discoveries Into Better Outcomes, Better Quality of Life. PMID: 28712096 Oncology (Williston Park) 2017 Jul;31(7):521-529.

• Clinical

  Board Certifications

  • American Board of Internal Medicine/Medical Oncology
  • American Board of Internal Medicine/Hematology