Departments & Divisions
Diego J Maselli Caceres, M.D.
Professor/Chief
Dr. Maselli completed his medical training in the Universidad Francisco Marroquin in Guatemala before completing a residency in Internal Medicine at University of Texas in Houston and fellowship in Pulmonary Diseases & Critical Care at UT Health San Antonio. In 2016, he founded the Severe Asthma Program at the University Health System in San Antonio. Dr. Maselli has published more than 50 peer-reviewed articles and his research focuses on severe asthma, non-cystic fibrosis bronchiectasis, and COPD.
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Professional Background
Education
- 2012 - Clinical Fellowship - Pulmonary Disease/Critical Care - UT Health Science Center at San Antonio
- 2011 - Clinical Fellowship - Medicine/Pulmonary Disease - UT Health Science Center at San Antonio
- 2009 - Residency - Internal Medicine - UT Health Science Center at Houston
- 2007 - Internship - Internal Medicine - UT Health Science Center at Houston
- 2004 - MD - Medicine - Universidad Francisco Marroquin
- 1999 - BS - Medicine - Universidad Francisco Marroquin
Appointments
- 7/2016 - Medical Director, Severe Asthma Program - University Health SystemSan Antonio
- 1/2014 - Medical Director, Respiratory Care - Robert B. Green Campus, University Health SystemSan Antonio
- 7/2012 - Assistant Professor/Clinical and Director of Pulmonary Medicine at UHS Downtown Clinic - University of Texas Health Science Center San Antonio, Medicine, San Antonio
- 7/2012 - Staff Physician - University Hospital, University Health SystemSan Antonio
- 7/2012 - Staff Physician - South Texas Veterans Health Care System, Audie L. Murphy DivisionSan Antonio
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Instruction & Training
- 7/2012 - Present, Preceptor, University of Texas Medical School at Houston
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Research & Grants
Grants
Federal
Funding Agency NIH Title The Genetic Epidemiology of COPD: COPDGene study (U01HL089897, U01HL089856) Status Active Period 1/2007 - Present Role Co-Investigator Grant Detail The Genetic Epidemiology of COPD: COPDGene study is an ongoing observational study to understand the epidemiology, genetics and radiographic characteristics of patients with COPD and patients at risk of COPD (U01HL089897, U01HL089856)
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Publications
Abstract
Maselli DJ, Amalakuhan B, Yen A, Washko GR, Diaz AA, Anzueto A, Restrepo MI. The prevalence and clinical characteristics of bronchiectasis in smokers with and without COPD: an analysis of the COPDGene Cohort San Antonio, Texas; 2017 May. (UT Health Medicine Research Day). Estrada RA, Maselli DJ, Peters JI. Severe Dyspnea: A bone of Contention. American Thoracic Society Annual Meeting Washington, DC: American Thoracic Society; 2017 May. (ATS Annual Meeting). Saikumar HP, Maselli DJ, Nambiar AN. With ChILD- A case of Antisynthetase Syndrome in Pregnancy Washington, DC: American Thoracic Society; 2017 May. (ATS Annual Meeting). Maselli DJ, Yen A, Amalakuhan B, McLean E, Washko GR, San Jose Estepar R, Diaz AA. Bronchiectasis is Associated with Acute Respiratory Disease Episodes in Smokers with and without COPD: An Analysis of the COPDGene Cohort Washington, DC: American Thoracic Society; 2017 May. (ATS Annual Meeting). Maselli DJ, Rahaghi FN, Yen A, San Jose Estepar R, Washko GR, Diaz AA. Pulmonary Vascular pruning is associated with bronchiectasis severity and lung function in smokers Washington, DC: American Thoracic Society; 2017 May. (ATS Annual Meeting). Maselli DJ, Zatikyan N, Stephens B, Velez MI, Burguete SR, Keyt H, Levine SM, Restrepo MI, Angel LF, Levine DJ. The role of Fraction of exhaled Nitric Oxide (FeNO) in allograft dysfunction in lung transplant recipients San Antonio, Texas; 2017 May. (UT Health Medicine Research Day). Maselli DJ, Diaz AA, Budoff MJ, Kim V, Putcha N, van Beek EJR, Foreman MG, Kinney GL, Hokanson JE, Curtis JL, Martinez FJ, Allen T, Bowler RP, Regan EA, Make BJ, Hanania NA, Han MK, Martinez CH. Impact of Cardiovascular Comorbidities on FEV1 Change in Smokers: An Analysis of the COPDGene Cohort San Francisco, California: American Thoracic Society; 2016 May. (ATS Annual Meeting). Hardin ME, Cho MH, McDonald ML, Castaldi PJ, Tal-Singer R, Maselli DJ, Make BJ, Crapo JD, Bowler RP, Silverman EK, Hersh CP. A Multi-Omics Approach Identifies Inflammatory Patterns In The Asthma-COPD Overlap Syndrome San Francisco, California: American Thoracic Society; 2016 May. (ATS Annual Meeting). Biguria JF, Maselli DJ, Salas Milan J. Sudden Dextrocardia? Montreal, Canada: American College of Chest Physicians; 2015 Oct. (CHEST Annual Meeting). Habib S, King P, Blower K, Maselli DJ, Anstead G. The casts that take your breath away Montreal Canada: American College of Chest Physicians; 2015 Oct. (CHEST Annual Meeting). Hardin M, Putcha N, Hansel N, Ramsdell JW, Van Beek E, Hanania NA, Maselli DJ, Woodruff PG, Ward CK, Martin UJ, Hersh CP, Bowler RP. The Significance of Peripheral Blood Eosinophils and IgE Levels in COPDGene Subjects Denver, Colorado: American Thoracic Society; 2015 May. (ATS Annual Meeting). Nazarullah A, Kha V, Maselli DJ, Nilson R, Jagirdar J. Granulomatous lung disease: Incidence and etiologies over the past 10 years in a large referral center Austin, Texas: American College of Chest Physicians; 2014 Oct. (CHEST Annual Meeting). Faverio P, Maselli DJ, Arango A, Fernandez J, Restrepo MI. Is age associated with different bronchiectasis etiologies? Madrid, Spain: American College of Chest Physicians; 2014 Mar. (CHEST World Conference). Rhodes D, Maselli DJ, Peters JI, Gardner D. Asthma Educational Awareness Program of North East Independent School District / University of Texas Health Science Center-San Antonio Austin, Texas; 2014 Feb. (Innovations in Health Science Education Annual Conference). Maselli DJ, Fernandez JF, Sibila O, Lacerna E, Anzueto A, Restrepo MI. Monotherapy vs. Combination Antibiotic Therapy for Patients Admitted for Pseudomonas Community-Acquired Pneumonia Chicago, Illinois: American College of Chest Physicians; 2013 Oct. (CHEST Annual Meeting). Maselli DJ, Medina, J, Dube PH, Brooks EG, Coalson JJ, Peters JI. Identification of CARDS Toxin in the Bronchial Epithelial Lining Fluid After Mycoplasma pneumoniae (Mp) Inoculation: A Primate Model Chicago, Illinois; 2013 Oct. (CHEST Annual Meeting). Maselli DJ, Fernandez JF, Faveiro P, Arango A, Restrepo MI. Idiopathic Bronchiectasis Less Common Than Predicted: Quality Improvement Project Chicago, Illinois: American College of Chest Physicians; 2013 Oct. (CHEST Annual Meeting). Diaz K, Maselli DJ, Rivera M, Levine SM. Costal Exostosis: A Rare Cause of Hemothorax Atlanta, Georgia: American College of Chest Physicians; 2012 Oct. (CHEST Annual Meeting). Maselli DJ, Peters J, Medina J, Brooks E, Kannan T, Coalson J, Cagle M, Baseman J, Dube P. Immunologic And Histological Response To Mycoplasma Pneumoniae (Mp) And Mycoplasma Toxin In A Primate Model. American Thoracic Society Annual Meeting: American Thoracic Society; 2012 May. (ATS Annual Meeting). Stewart JI, Maselli DJ, Anzueto A, Criner GJ, Han FK, Martinez FJ, Lynch DA, Make BJ. Clinical Impact Of CT Radiological Feature Of Bronchiectasis In The COPDGene Cohort San Francisco, California: American Thoracic Society; 2012 May. (ATS Annual Meeting). Peters J, Diaz J, Maselli DJ. Impact of Omalizumab in Asthmatics with IgE Levels > 700 IU/ml Honolulu, Hawaii: American College of Chest Physicians; 2011 Oct. (CHEST Annual Meeting). Maselli DJ, Diaz J, Peters J. Omalizumab in patients with IgE levels > 700 IU/ml Amsterdam, Netherlands: European Respiratory Society; 2011 Sep. (ERS Annual Meeting). Maselli DJ, Mullerova H, Locantore N, Vestbo J, Hurst J, Wedzicha J, Anzueto A. Risk factors and Mortality Associated with Hospitalized Chronic Obstructive Pulmonary Disease (COPD) Exacerbations During the 3-Year Follow-Up in the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Cohort Denver, Colorado: American Thoracic Society; 2011 May. (ATS Annual Meeting). Maselli DJ, Desa P, Stupka E, Levine S, Peters J. A reversed-halo sign in a patient with jaundice and no respiratory symptoms Denver, Colorado: American Thoracic Society; 2011 May. (ATS Annual Meeting). Ibrahim M, Maselli DJ, Fenari Z. Acute renal failure, hepatitis, rhabdomyolysis and left ventricular decompensation induced by olanzapine Houston, Texas: American College of Physicians; 2008 Apr. (ACP Meeting, Texas Chapter). Awad O, Maselli DJ, Estrada-Y-Martin RM. Patient`s acceptance for the advanced monitoring systems in electronic intensive care units Chicago, Illinois: American College of Chest Physicians; 2007 Oct. (CHEST Annual Meeting). Maselli DJ, Alviar CL. Aspergillus pericarditis Galveston, Texas: American College of Physicians; 2007 Mar. (ACP Meeting, Texas Chapter). Maselli DJ, DeAguirre M, Garcia V. Tuberous Sclerosis Guatemala City, Guatemala; 2004 Jan. (Cleveland Clinic Annual Meeting).
Book Chapter
Amalakuhan B, Maselli DJ, Anzueto A. Chapter 5: Exacerbations of COPD. In: Jenkins C, Miravitlles M. 100 Key Questions on COPD. Barcelona, Spain: Permanyer; 2015. p. 39-44. Maselli DJ, Restrepo MI. Chapter 13: Pneumonia or exacerbation of COPD?. In: Anzueto A, Heijdra Y, Hurst JR. Controversies in COPD. Sheffield, UK: European Respiratory Society Publications; 2015. p. 185-196.
Journal Article
Maselli DJ, Medina JL, Brooks EG, Coalson JJ, Kannan TR, Winter VT, Principe M, Cagle MP, Baseman JB, Dube PH, Peters JI. The immunopathologic effects of Mycoplasma pneumoniae and CARDS toxin: a primate model Am J Respir Cell Mol Bio 2017 Sep;. Maselli DJ, Keyt H, Restrepo MI. Inhaled Antibiotic Therapy in Chronic Respiratory Diseases Int J Mol Sci 2017 May;18(1062):1-23. Maselli DJ, Amalakuhan B, Keyt H, Diaz AA. Suspecting non-cystic fibrosis bronchiectasis: What the busy primary care clinician needs to know International Journal of Clinical Practice 2017 Feb;71(2). Maselli DJ, Peters JI. In refractory chronic cough, physiotherapy plus speech and language therapy improved quality of life at 4 weeks Annals of Internal Medicine 2017 Jan;166(2). Diaz AA, Young TP, Maselli DJ, Martinez CH, Maclean ES, Yen A, Dass C, Simpson SA, Lynch DA, Kinney GL, Hokanson JE, Washko GR, San Jose Estepar R. Bronchoarterial ratio in never-smokers adults: Implications for bronchial dilation definition Respirology 2017 Jan;. Habib SA, Maselli DJ. Can Quality Improvement Initiatives With Organizational Changes Improve the Delivery of Asthma Care? Repiratory Care 2016 Dec;61(12):1706-1707. Diaz AA, Young TP, Maselli DJ, Martinez CH, Gill R, Nardelli P, Wang W, Kinney GL, Hokanson JE, Washko GR, San Jose Estepar R. Quantitative CT measures of bronchiectasis in smokers Chest 2016 Nov;. Maselli DJ, Velez MI, Rogers L. Reslizumab in the management of poorly controlled asthma: the data so far Journal of Asthma and Allergy 2016 Aug;9:155-162. Maselli DJ, Peters JI. ACP Journal Club. Review: In COPD, tiotropium improves lung function and reduces adverse events compared with ipratropium bromide Annals of Internal Medicine 2016 Jan;164(2):6-6. Amalakuhan B, Maselli DJ, Martinez-Garcia MA. Update in Bronchiectasis 2014 American Journal of Respiratory and Critical Care Medicine 2015 Nov;192(10):1155-1161. Maselli DJ, Keyt H, Rogers LJ. Profile of lebrikizumab and its potential in the treatment of asthma Journal of Asthma and Allergy 2015 Aug;10(8):87-92. Maselli DJ, Peters JI. Review: Adding tiotropium to ICSs alone or with LABAs improves pulmonary function in asthma Annals of Internal Medicine 2015 Jun;162(12):5-5. Maselli DJ. Risk factors and antibiotic therapy in P. aeruginosa community-acquired pneumonia Respirology 2015 May;20(4):660-666. Mullerova H, Maselli DJ, Locantore N, Vestbo J, Hurst JR, Wedzicha J, Bakke P, Agusti A, Anzueto A. Hospitalized Exacerbations of Chronic Obstructive Pulmonary Disease: Risk Factors and Outcomes in the ECLIPSE Cohort Chest 2015 Apr;147(4):999-1007. Nazarullah A, Nilson R, Maselli DJ, Jagirdar J. Incidence and aetiologies of pulmonary granulomatous inflammation: A decade of experience Respirology 2015 Jan;20(1):115-121. Laserna E, Sibila O, Fernandez JF, Maselli DJ, Mortensen EM, Anzueto A, Waterer G, Restrepo MI. Impact of Macrolide Therapy in Patients Hospitalized With Pseudomonas aeruginosa Community-Acquired Pneumonia Chest 2014 May;145(5):1114-1120. Maselli Caceres D. Biologics inch ahead in asthma treatment Chest Physician 2013 2013 Dec;8(12):10-11. Gabehart, KE, Royce, S, Maselli DJ, Miyasato, S, Davis, E, Tang, M, Le Saux CJ. Airway hyperresponsiveness is associated with airway remodeling but not inflammation in aging Cav1-/- mice Respiratory Research 2013 Dec;14(110). Maselli DJ, Peters JI. 5 days of prednisone was noninferior to 14 days in patients with acute COPD exacerbation Annals of Internal Medicine 2013 Sep;159(6). Maselli DJ, Singh H, Diaz J, Peters JI. Efficacy of omalizumab in asthmatic patients with IgE levels above 700 IU/mL: a retrospective study Annals of Allergy Asthma and Immunology 2013 Jun;:457-461. Maselli DJ, Adams SG, Peters JI, Levine SM. Management of asthma during pregnancy Therapeutic Advances in Respiratory Diseases 2013 Apr;7(2):87-100. Maselli DJ, Fernandez JF. Can respiratory therapist-driven protocols improve resource utilization? Respiratory Care 2013 Mar;58(3):546-547. Ibrahim M, Maselli DJ, Hasan R, Hamilton A. Safety of β-blockers in the acute management of cocaine-associated chest pain American Journal of Emergency Medicine 2013 Mar;31(3):613-616. Burguete SR, Maselli DJ, Fernandez Juan Felipe, Levine SM. Lung Transplant Infection Respirology 2013 Jan;11440(1843):22-28. Maselli DJ, Fernandez, Juan F. Computed tomography imaging for Mycobacterium xenopi infections, a clearer path for diagnosis? Respirology 2012 Dec;18:1-2. Fernandez JF, Maselli DJ, Simpson T, Restrepo MI. Pulmonary Mucormycosis: What Is the Best Strategy for Therapy? Respiratory Care 2012 Oct;58(5). Maselli DJ, Anzueto A. The need to further understand who gets hospitalized for a COPD exacerbation Multidisciplinary Respiratory Research 2012 Jun;7(1):7-7. Burguete SR, Fernandez, Juan Felipe, Maselli DJ, Levine SM. Pulmonary Hypertension as a risk factor for graft dysfunction, ultrasound-guided subclavian vein cannulation, and lebrikizumab for adult asthma. Beyond the Blue: What Fellows are Reading in Other Journals Am J Respir Crit Care Med 2012 Feb;185(2):223-224. Maselli DJ, Fernandez J, Whong CY, Echevarria K, Nambiar AM, Anzueto AR, Restrepo MI. Clinical evaluation of the role of ceftaroline in the management of community acquired bacterial pneumonia Infect Drug Resist 2012 Feb;5:43-51. Maselli DJ, Adams SG, Peters JI. The role of anti-infectives in the treatment of refractory asthma Therapeutic Advances in Respiratory Disease 2011 Dec;5(6):387-396. Maselli DJ, Restrepo MI. Strategies in the Prevention of Ventilator-Associated Pneumonia Therapeutic Advances in Respiratory Diseases 2011 Apr;5(2):131-141. Maselli D, Richey, S. Racoon Eyes Consultant 2009 Jun;49(6):393-393. Politano S, Maselli DJ, Zenali MJ, Nguyen A, Quintas-Cardama A. Bone marrow fibrosis and gelatinous bone marrow atrophy associated with acute Epstein-Barr virus infection American Journal of Hematology 2008 Jul;83(7):606-607.
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Clinical
Board Certifications
- American Board of Internal Medicine/Pulmonary Disease
- American Board of Internal Medicine/Critical Care Medicine