Su-Hyuk Ko, Ph.D.

• Professional Background

  Education

  • 2016 - Ph.D. - Hanyang University Graduate School of Biomedical Science and Engineering

  Training

  • 2022 - Postdoctoral fellow - Department of Molecular Medicine, UT Health SA
  • 2017 - Postdoctoral fellow - Department of Microbiology, College of Medicine, Hanyang University

  Appointments

  • 2022 - Present - Instructor/Research - Cell Systems & Anatomy

• Research & Grants

  Study of the regenerative capacity of damaged mechanosensory and GABAergic neurons.
  The signaling mechanism regulating the regeneration ability of neurons damaged by laser axotomy is explored through various genetic mutations, transgene models, and drug treatments.

  A study of the effects of cell death mechanisms such as autophagy and ferroptosis on the maintenance/recovery of neuronal function.
  Transect/resuture the sciatic nerve of the animal model, then observe their behavior. We recently found that axonal fusion, which is the most efficient way for damaged neurons to restore their function, occurs under certain conditions.

• Publications

  • GPX modulation promotes regenerative axonal fusion and functional recovery after injury through PSR-1 condensation
  • Autophagy regulation and function in axon regeneration: new insights from Caenorhabditis elegans
  • Axon Injury-Induced Autophagy Activation Is Impaired in a C. elegans Model of Tauopathy
  • Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH