Dharam Kaushik, M.D.
Society of Urologic Oncology Fellowship Program Director
Dr. Dharam Kaushik is an Associate Professor and program director of urologic oncology fellowship in the department of urology at the University of Texas Health San Antonio. He completed his urology surgical residency at the University of Nebraska Medical Center, Omaha, Nebraska and clinical fellowship in urologic oncology with leaders in cancer surgery at Mayo Clinic, Rochester, Minnesota. Dr. Kaushik has expertise in surgical management of advanced renal cell carcinoma, including with complex tumor thrombus, retroperitoneal lymph node dissection for testicular cancer, bladder cancer, radical cystectomy, orthotopic neobladder reconstruction, robotic and open complex partial nephrectomy, penile and urethral cancer, inguinal lymph node dissection and salvage prostatectomy for post radiation failure in prostate cancer.
Dr Kaushik’s primary research interests include renal cell carcinoma with tumor thrombus, detection of novel biomarkers, newer therapeutic targets and studying mechanism of drug resistance in renal cell carcinoma, evaluating effect of exercise (Yoga) in urologic cancer.
- 2014 - Clinical Fellowship - Urology Oncologic Surgery - Mayo Clinic
- 2014 - Postdoctoral Training - Clinical and Translational Science Research - Mayo Clinic
- 2012 - Residency - Urology - University of Nebraska Medical Center
- 2008 - Residency - Urology - University of Nebraska Medical Center
- 2006 - Residency - General Surgery - North Shore University Hospital
- 2005 - Postdoctoral Training - Research Associate-Cellular and Stress Biology - Roswell Park Cancer Institute
- 2003 - Residency - General Surgery - Amritsar Medical College
- 2000 - BM BS - Medicine and Surgery - Mysore Medical College
- 1999 - Internship - Urology - Mysore Medical College
- 10/2014 - Program Director of Urologic Oncology Fellowship and Director - University of Texas Health, San Antonio, Texas, Urology, San Antonio
- 7/2014 - Assistant Professor Division of Urologic Oncology and Attending Staff - University of Texas Health Science Center at San Antonio, Urology, San Antonio
Instruction & Training
- - Present, Multidisciplinary Genitourinary Tumor Board
- 6/2016 - Present, American Board of Urology Prep Course
Research & Grants
Funding Agency National Center for Advancing Translational Sciences, NIH UL1 TR 001120 Title To compare radical cystectomy with chemo-radiation therapy for muscle invasive bladder cancer and evaluate biomarkers for chemo-radiation resistant bladder cancer patients Status Active Period - Present Role Principal Investigator Grant Detail This is a pilot randomized clinical trial to determine and quantify quality of life in patients treated with radical cystectomy and chemo radiation therapy. In addition we will determine and quantify progression free survival and bladder-intact survival in patients treated with radical cystectomy and chemoradiation therapy. We will evaluate genetic markers predicting response to chemoradiation by performing tissue RNA microarrays. Lastly we will assess the feasibility of conducting an adequately powered non-inferiority trial of the same design via recruitment rate, patient adherence to both treatment arm, and attrition.
Funding Agency Littenberg Foundation Title Department of Urology/Urology Oncology, Littenberg Foundation Grant ($8,774) to develop Tissue Microarray Technology for High-Throughput Molecular Profiling of Renal Cell Carcinoma with Venous Tumor Thrombus. Status Active Period - Present Role Principal Investigator Grant Detail Purpose of this grant is to develop Tissue Micro-Array (TMA) from kidney cancer and tumor thrombus patient. This TMA can be combined with immunohistochemistry analysis to define the clinical significance of altered expression of cell cycle-related molecules, or any other markers that may be deemed important. We are in the process of identifying candidate markers. Developing this TMA containing samples from kidney cancer and tumor thrombus would potentially assist us in determining downstream protein expression and possible molecules for targeting with drug delivery. Funding Agency ThriveWell Foundation Title ThriveWell Cancer foundation grant ($25,000) for the Study Impact of Yoga intervention on quality of life, immune and pro-inflammatory biomarkers in prostate cancer patients scheduled for radical prostatectomy Status Active Period 7/2015 - Present Role Principal Investigator Grant Detail Primary Objectives of this study is-
1.To determine the effect of preoperative and postoperative Yoga complementary therapy on quality of life (QoL), fatigue, Six-Minute Walk Test, recovery of urinary continence, recovery of erectile function in patients with prostate cancer who underwent radical prostatectomy.
2.To assess the feasibility of conducting an adequately powered trial of the same design via recruitment rate, adherence, attrition, and safety.
1.To determine the effect of Yoga on pro-inflammatory biomarkers: IFN-gamma, TNF-alpha, IL-6, IL-17, IL-1, and IL-10 & TGF-BETA.
2.To determine the effect of Yoga on cellular immune response by measuring activity of Natural Killer (NK) cell and regulatory T-cell: (Th1, Th2, Treg, Th17, CTL & NK cells)
- American Board of Urology