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Sakie Katsumura

Departments & Divisions

Sakie Katsumura

Assistant Professor/Research

  • Professional Background

    Education

    • 2023 - Research Scientist - Cancer Metabolism, Aging - UT Health San Antonio
    • 2022 - Postdoctoral Fellowship - Cancer and Energy Metabolism - UT Health San Antonio
    • 2017 - Ph.D. - Clinical training - Maxillofacial Surgery - Tokyo Medical and Dental University
    • 2013 - Residency - Oral Surgery - Tokyo Medical University Hospital

    Appointments

    • 11/2023 - Assistant Professor/Research - Cancer Metabolism, Aging - UT Health San Antonio

  • Publications

      Katsumura S, Morita M, Regulation of energy metabolism through mRNA degradation of GDF15 and FGF21: Exploring new strategy for obesity treatment, Experimental Medicine, Neuron-mediated metabolic and inflammatory control and biological homeostasis, 2023.

      Katsumura S, Siddiqui N, Goldsmith MR, Cheah JH, Fujikawa T, Minegishi G, Yamagata A, Yabuki Y, Kobayashi K, Shirouzu M, Inagaki T, Huang TH, Musi N, Topisirovic I, Larsson O, Morita M. Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure. Cell Metab. 2022;34(4):564-80 e8. Epub 2022/04/07. doi: 10.1016/j.cmet.2022.03.005.
      This research was highlighted by Nat Rev Endocrinol., CNOT6L regulates hepatokine expression, 2022 Jul;18(7):392. Epub 2022/05/06. doi: 10.1038/s41574-022-00684-5.

      O'Dwyer C, Yaworski R, Katsumura S, Ghorbani P, Gobeil Odai K, Nunes JRC, LeBlond ND, Sanjana S, Smith TTK, Han S, Margison KD, Alain T, Morita M, Fullerton MD. Hepatic Choline Transport Is Inhibited During Fatty Acid-Induced Lipotoxicity and Obesity. Hepatol Commun. 2020;4(6):876-89. Epub 2020/06/04. doi: 10.1002/hep4.1516.

      *Pearl D, *Katsumura S, Amiri M, Tabatabaei N, Zhang X, Vinette V, Pang X, Beug ST, Kim SH, Jones LM, Robichaud N, Ong SG, Jia JJ, Ali H, Tremblay ML, Jaramillo M, Alain T, Morita M, Sonenberg N, Tahmasebi S. 4E-BP-Dependent Translational Control of Irf8 Mediates Adipose Tissue Macrophage Inflammatory Response. J Immunol. 2020;204(9):2392-400. Epub 2020/03/28. doi: 10.4049/jimmunol.1900538.

      Morita M, Siddiqui N, Katsumura S, Rouya C, Larsson O, Nagashima T, Hekmatnejad B, Takahashi A, Kiyonari H, Zang M, St-Arnaud R, Oike Y, Giguere V, Topisirovic I, Okada-Hatakeyama M, Yamamoto T, Sonenberg N. Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis. Proc Natl Acad Sci U S A. 2019;116(16):7973-81. Epub 2019/03/31. doi: 10.1073/pnas.1816023116.

      Morita M, Prudent J, Basu K, Goyon V, Katsumura S, Hulea L, Pearl D, Siddiqui N, Strack S, McGuirk S, St-Pierre J, Larsson O, Topisirovic I, Vali H, McBride HM, Bergeron JJ, Sonenberg N. mTOR controls mitochondrial dynamics and cell survival via MTFP1. Mol Cell. 2017;67(6):922-35 e5. Epub 2017/09/19. doi: 10.1016/j.molcel.2017.08.013.

      Katsumura S, Izu Y, Yamada T, Griendling K, Harada K, Noda M, Ezura Y. FGF Suppresses Poldip2 Expression in Osteoblasts. J Cell Biochem. 2017;118(7):1670-7. Epub 2016/12/06. doi: 10.1002/jcb.25813.

      Katsumura S, Ezura Y, Izu Y, Shirakawa J, Miyawaki A, Harada K, Noda M.  Beta Adrenergic Receptor Stimulation Suppresses Cell Migration in Association with Cell Cycle Transition in Osteoblasts-Live Imaging Analyses Based on FUCCI System. J Cell Physiol. 2016;231(2):496-504. Epub 2015/07/21.

  • Clinical

    Board Certifications

    • Board Certification-Japanese Society of Oral and Maxillofacial Surgeons