- 1996 - MS - Medical Biochemistry - Shandong Medical University
- 1991 - MD - Medicine - Qingdao Medical College
- Postdoctoral Fellowship - Molecular Therapy (Cardiovascular Disease) - UTHSCSA
- Postdoctoral Fellowship - Immunogenetics (HIV/AIDS) - UTHSCSA
- 10/2009 - Assistant Professor - Uni. Texas Heath. Sci. Ctr. San Antonio, Medicine, San Antonio
Instruction & Training
- 1/2007 - Present, Visiting Graduate Students, UTHSCSA
- 7/2006 - Present, Pre-Doctoral Student Supervision, UTHSCSA
- 1/2005 - Present, Pre-Doctoral Student Supervision, UTHSCSA
- 5/2004 - Present, Undergraduate Student Supervision, UTHSCSA
Research & Grants
U.S. Air Force Medical Service Research Program
Predictors of Immune Status and Diseases (PI-Jason Okulicz)
9/2016 - 8/2018
The proposed work will use Genetics Genomics Proteomics (G2P) technologies to identify determinants of immune/inflammatory responses and disease outcomes will improve precision military medicine and provide novel therapeutic targets.
My role on this grant: I helped in the design of this study. I am involved in cohort development, liaison with cohort collaborators, administrative duties related to ongoing research, in charge of database, inventory and genetic genomics, handling and maintenance of all equipment, conduct of large scale genetic studies both with GWAS and traditional approaches. Expertise in NGS-related technologies including RNA-seq.
Department of Veterans Affairs
Center for Personalized Medicine (PI-Sunil Ahuja)
4/2014 - 3/2018
This Program Project Grant supports three thematic projects and a core for carrying out research on the pathogenesis of HIV/AIDS, with an emphasis on host genetic and epigenetic determinants of susceptibility, disease progression, and response to therapy.
My role on this grant: I am the director of the PPG core. I have been intimately involved in establishing and maintaining smooth functioning of the Illumina based equipment we have at the STVHCS Core in the Center for Personalized Medicine (CPM). I have excellent working relationships with all Principal Investigators and all Heads of Units for the Core in the CPM. I am responsible for the day-to-day operation of the core and liaison with members of the Center of Personalized Medicine who oversee the Genomic, Bioinformatic, Clinical, and Administrative units of the Center. I am well versed with all the aspects of the studies in the PPG. In particular, I have high familiarity with all the platforms used in each unit of the Center; these include: sample processing, GWAS, next-generation sequencing, bioinformatics, transcriptomics, and the handling of large datasets. I interact with Dr. Sunil Ahuja and other PIs of the projects on a daily basis and assess the requirements of the various projects. I streamline the operations of the core in consultation with other members of the PPG and am responsible for optimal utilization of the core resources, quality control and security. Accompanied is the organizational chart of the CPM
Ahuja SK, Manoharan MS, Harper NL, Jimenez F, Hobson, BD,Martinez H, Ingale P, Liu Y-G, Carrillo A, Lou Z, Kellog DL, Ahuja SS, Rather CG, Esch RE, Ramirez DA, Clark RA, Nadeau K, Andrews CP, Jacobs RL, He W. Preservation of epithelial cell barrier function and muted inflammation in resistance to allergic rhinoconjunctivitis from house dust mite challenge J Allergy Clin Immunol 2016 Sep;. He W, Jimenez F, Martinez H, Harper NL, Manoharan MS, Carillo A, Ingale P, Liu Y, Ahuja SS, Clark RA, Rather CG, Ramirez DA, Andrews CP, Jacobs RL, Ahuja SK. Cockroach sensitization mitigates allergic rhinoconjunctivitis symptom severity in patients allergic to house dust mites and pollen J Allergy Clin Immunol 2015 Sep;136(3):658-666. Gornalusse G, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan M, Avadhanam N, Murthy KK, Martinez H, Molano Murillo AM, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich L, Karim SA, Martin JN, Deeks SJ, Hecht F, Sinclair E, Clark RA, Okulicz J, Valentine FT, Martinson N, Tiemessen CT, Ndung`u T, Hunt PW, He W, Ahuja SK. Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor Proc Natl Acad Sci (USA) 2015 Aug;112(34):E4762-E4771. Okulicz JF, Le T, Agan BK, Camargo J, Landrum ML, Wright EJ, Dolan MJ, Ganesan A, Ferguson TM, Smith DM, Richman DD, Little SJ, Clark RA, He W, Ahuja SK. Influence of the Timing of Anti-retroviral Therapy on Normalization of Immune Status in HIV-1 Infected Individuals JAMA Intern Med 2015 Jan;175(1):88-99. Le T, Wright EJ, Smith DM, He W, Catano G, Okulicz JF, Young JA, Clark RA, Richman DD, Little SJ, Ahuja SK. Enhanced CD4+ T-Cell Recovery with Earlier HIV-1 Antiretroviral Therapy NEJM 2013 Jan;368(3):218-230. Mamtani M, Mummidi S, Ramsuran V, Pham MH, Maldonado R, Begum K, Valera MS, Sanchez R, Castiblanco J, Kulkarni H, Ndunga??u T, He W, Anaya JM, Ahuja SK. Influence of Variations in CCL3L1 and CCR5 on Tuberculosis in a Northwestern Colombian Population J Infect Dis 2011 Jun;203(11):1590-1594.
He W. From the total of 38 peer-reviewed journal articles with citations of 887 times, average citation per items: 22.7, and H-index: 15. The citation report is from www.webofknowledge.com H-index Report 2016 Oct;.