Abhishek Gupta, PhD

Gupta A, You W, Han L, Ji J, Pan M, Han X, Sun X, Zhao P: Caspase-6 controls lipid and energy metabolism in diet-induced obesity. Advanced Science. advs.202514784. 2026.

Kumar S, Gupta A: From Molecules to Medicine: Deciphering Obesity and Lipid Metabolism for Translational Insights. Biomedicines. 2026.

Basri R, Balakrishnan B, Slayton M, Becker C, Hussein H, Puri I, Gupta A, Sharma V, Baumann C, Consitt L, Puri V. Role of muscle-specific Fsp27 in energy production and whole-body glucose homeostasis. Journal of Endocrine Society, 2025.

Varshney S, Kumar D, Choudhary R, Gupta A, Beg M, Shankar K, Rajan S, Srivastava A, Gupta S, Khandelwal N, Balaramnavar VM, Gaikwad AN: Flavopiridol inhibits adipogenesis and improves metabolic homeostasis by ameliorating adipose tissue inflammation in a diet-induced obesity model. Biomedicine and Pharmacotherapy 2024;179:117330. 

Balakrishnan B, Gupta A, Basri R, Sharma VM, Slayton M, Gentner K, Becker CC, Karki S, Muturi H, Najjar SM, Loria AS, Gokce N, Puri V. Endothelial-Specific Expression of CIDEC Improves High-Fat Diet-Induced Vascular and Metabolic Dysfunction. Diabetes, 2023. 

Gupta A, Balakrishnan B, Karki S, Slayton M, Jash S, Banerjee S, Grahn THM, Jambunathan S, Disney S, Hussein H, Kong D, Lowell BB, Natarajan P, Reddy UK, Gokce N, Sharma VM, Puri V. Human CIDEC transgene improves lipid metabolism and protects against high fat-diet induced glucose intolerance in mice. Journal of Biological Chemistry, 2022.

Slayton M, Balakrishnan B, Gupta A, Jobe S, Puri I, Neely S, Tamori Y, Russ DW, Yildrim G, Yakar S, Sharma VM, Puri V: Fsp27 plays a crucial role in muscle performance. American Journal of Physiology, Endocrinology and Metabolism 2022.

Gupta A, Balakrishnan B, Karki S, Slayton M, Gokce N, Sharma V, Puri V. Human Cidec transgene improves lipid metabolism and protects against high fat-diet induced glucose intolerance in mice. Journal of Endocrine Society, 2022.

Balakrishnan B, Gupta A, Sharma V, Slayton M, Gentner K, Karki S, Muturi H, Najjar SM, Loria AS, Gokce N, Puri V. Endothelial-specific expression of Cidec improves high-fat diet-induced vascular and metabolic dysfunction. Circulation Research, 2022. 

Gupta S, Mishra T, Varshney S, Kushwaha V, Khandelwal N, Rai P, Garg R, Dev K, Gupta A, Kumar D, Balaramnavar VM, Arya KR, Gayen JR, Narender T, Gaikwad AN. Coelogin ameliorates metabolic dyshomeostasis by regulating adipogenesis and enhancing energy expenditure in adipose tissue. Pharmacological Research 2021;172:105776.

Bele S, Girada SB, Ray A, Gupta A, Oruganti S, Babu PP, Rayalla RS, Kalivendi SV, Ibrahim A, Puri V, Adalla V, Katika MR, DiMarchi R, Mitra P. MS-275, a class 1 histone deacetylase inhibitor augments glucagon-like peptide-1 receptor agonism to improve glycemic control and reduce obesity in diet-induced obese mice. Elife 2020 ;9:e52212.

Slayton M, Gupta A, Balakrishnan B, Puri V. CIDE Proteins in Human Health and Disease. Cells 2019, 8(3):238

Shankar K, Kumar D, Gupta S, Varshney S, Rajan S, Srivastava A, Gupta A, Gupta AP, Vishwakarma AL, Gayen JR, Gaikwad AN: Role of Brown Adipose Tissue in Modulating Adipose Tissue Inflammation and Insulin Resistance in HFD fed Mice. European Journal of Pharmacology 2019, 854:354-364.

Kumar D, Pandya SK, Varshney S, Shankar K, Rajan S, Srivastava A, Gupta A, Gupta S, Vishwakarma AL, Misra A, Gaikwad AN: Temporal immunometabolic profiling of adipose tissue in HFD-induced obesity: Manifestations of mast cells in fibrosis and senescence. “International Journal of Obesity” 2019.

Singh P, Bajpai V, Gupta A, Gaikwad AN, Murya R, Kumar B. Identification and quantification of secondary metabolites of Pterocarpus marsupium by LC–MS techniques and its in-vitro lipid lowering activity. Industrial crops and products.  2018, 127:26-35. 

Rajan S, Satish S, Shankar K, Pandeti S, Varshney S, Srivastava A, Kumar D, Gupta A, Choudhary R, Balaramnavar V, Tadigoppula N, Gaikwad AN: Aegeline inspired synthesis of novel β3-AR agonist improves insulin sensitivity in vitro and in vivo models of insulin resistance. Metabolism: Clinical & Experimental 2018;85:1-13.

Srivastava A, Shankar K, Beg M, Rajan S, Gupta A, Varshney S, Kumar D, Gupta S, Mishra RK, Gaikwad AN: Chronic Hyperinsulinemia Induced miR-27b is Linked to Adipocyte Insulin Resistance by Targeting Insulin Receptor. Journal of Molecular Medicine 2018;96;3-4:315-331.

Rajan S, Puri S, Kumar D, Hari Babu M, Shankar K, Varshney S, Srivastava A, Gupta A, Sridhar Reddy M, Gaikwad AN: Novel Indole And Triazole Based Hybrid Molecules Exhibit Potent Anti-Adipogenic And Antidyslipidemic Activity By Activating Wnt3a/β-Catenin Pathway. European Journal of Medicinal Chemistry, 2018;143:1345-1360.

Rajan S, Panzade G, Srivastava A, Shankar K, Pandey R, Kumar D, Gupta S, Gupta A, Varshney S, Beg M, Mishra RK, Shankar R, Gaikwad AN. miR-876-3p regulates glucose homeostasis and insulin sensitivity by targeting adiponectin. Journal of Endocrinology 2018;17:0387.

Kumar D, Shankar K, Patel S, Gupta A, Varshney S, Gupta S, Rajan S, Srivastava A, Vishwakarma AL, Gaikwad AN: Chronic hyperinsulinemia promotes meta-inflammation and extracellular matrix deposition in adipose tissue: Implications of nitric oxide. Molecular and Cellular Endocrinology: pii: S0303-7207(18)30158-8. 2018.

Gupta A, Kumar A, Kumar D, Shankar K, Varshney S, Rajan S, Srivastava A, Gupta S, Narender T, Gaikwad AN: Ecliptal, a promising natural lead isolated from Eclipta alba modulates adipocyte function and ameliorates metabolic syndrome. Toxicology & Applied Pharmacology 2018;338:134-147.

Gupta A, Beg M, Kumar D, Shankar K, Varshney S, Rajan S, Srivastava A, Singh K, Sonkar S, Mahdi AA, Dikshit M, Gaikwad AN: Chronic hyper-leptinemia induces insulin signaling disruption in adipocytes: Implications of NOS2. Free Radical Biology & Medicine 2017;112:93-108.

Gupta A, Singh VK, Kumar D, Yadav P, Kumar S, Beg M, Shankar K, Varshney S, Rajan S, Srivastava A, Choudhary R, Balaramnavar VM, Bhatta R, Tadigoppula N, Gaikwad AN: Curcumin-3,4-Dichloro Phenyl Pyrazole (CDPP) overcomes curcumin's low bioavailability, inhibits adipogenesis and ameliorates dyslipidemia by activating reverse cholesterol transport. Metabolism: Clinical and Experimental 2017;73:109-124.

Gupta A, Kumar A, Kumar D, Shankar K, Varshney S, Rajan S, Srivastava A, Gupta S, Narender T, Gaikwad AN: Ethyl acetate fraction of Eclipta alba: a potential phytopharmaceutical targeting adipocyte differentiation. Biomedicine & Pharmacotherapy 2017;96:572-583.

Kumar D, Goand UK, Gupta S, Shankar K, Varshney S, Rajan S, Srivastava A, Gupta A, Vishwakarma AL, Srivastava AK, Gaikwad AN: Saroglitazar reduces obesity and associated inflammatory consequences in murine adipose tissue. European Journal of Pharmacology 2017.

Rajan S, Shankar K, Beg M, Varshney S, Gupta A, Srivastava A, Kumar D, Mishra RK, Hossain Z, Gayen JR, Gaikwad AN: Chronic hyperinsulinemia reduces insulin sensitivity and metabolic functions of brown adipocyte. The Journal of Endocrinology 2016;230(3):275-90.

Beg M, Srivastava A, Shankar K, Varshney S, Rajan S, Gupta A, Kumar D, Gaikwad AN: PPP2R5B, a regulatory subunit of PP2A, contributes to adipocyte insulin resistance. Molecular and Cellular Endocrinology 2016;437:97-107.

Shankar K, Singh SK, Kumar D, Varshney S, Gupta A, Rajan S, Srivastava A, Beg M, Srivastava AK, Kanojiya S, Mishra DK, Gaikwad AN: Cucumis melo ssp. Agrestis var. Agrestis Ameliorates High Fat Diet Induced Dyslipidemia in Syrian Golden Hamsters and Inhibits Adipogenesis in 3T3-L1 Adipocytes. Pharmacognosy Magazine 2015;11:S501-510.

Rajan S, Gupta A, Beg M, Shankar K, Srivastava A, Varshney S, Kumar D, Gaikwad AN: Adipocyte transdifferentiation and its molecular targets. Differentiation; Research in Biological Diversity 2014;87:183-192.