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Director of Basic Science Research

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210-450-8094

glatt@uthscsa.edu

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Departments & Divisions

Vaida Glatt, PhD

Assistant Professor

Director of Basic Science Research

Department of Orthopaedics

Dr. Vaida Glatt is an Assistant Professor and the Director of Research at the Department of Orthopaedic Surgery at the University of Texas Health Science Center in San Antonio, USA. She completed her postdoctoral fellowships at the Center for Advanced Orthopaedic Studies, Harvard Medical School, and the Julius Wolff Institute for Biomechanics and Musculoskeletal Regeneration in Berlin, Germany. In 2012, Dr. Glatt joined the Trauma Research Group at Institute of Health and Biomedical Innovation, Queensland University of Technology in Brisbane, Australia, as a Senior Research Fellow. Soon after arriving in Australia, she was awarded the Vice-Chancellor’s Research Fellowship to continue her research work.

Since then, she has acquired extensive research expertise in the musculoskeletal field with a focus on bone regeneration and healing by using preclinical and translational in vivo models to develop novel treatments. One of her primary research focuses is in the field of mechano-biology, which is the study of the interactions between mechanical and biological factors to develop and explain the influence of mechanical conditions on the progression of bone healing. In fact, she was the first in the field to accelerate bone healing by a process called Reversed Dynamization. Additionally, Dr. Glatt’s focus is on tissue regenerative medicine where she is actively developing therapies to improve the regeneration of bone tissue by means of improving the effectiveness of bone morphogenetic protein 2 (BMP-2) while minimizing the side effects and doses required. Based on this research, she developed a natural carrier, the Biomimetic Hematoma, and filed a provisional patent in 2018 through the Office of Technology Commercialization, UTHSCSA. This proprietary patent relates to the compositions and methods of improving treatment and accelerating the healing of complex bone injuries such as large bone defects in patients. Furthermore, in 2020, she was awarded President’s Translational and Entrepreneurial Research Fund (PTEF) from UTHSCSA to continue this technology towards a clinical application. Dr. Glatt is also involved with multidisciplinary projects on musculoskeletal research with collaborators on nearly every continent.

Dr. Glatt is the author of over 70 publications in peer-reviewed journals and is a contributing book author. She has presented her work at over 60 international conferences, is a sought out speaker and lecturer at various top international universities, has editorial responsibilities with multiple international journals, is a reviewer for the AO Foundation grant applications, and is a member of three major societies in the field. Dr. Glatt has received local, national, and international research grants in the field of bone healing, including being awarded several grants from the AO Foundation, and later awarded with substantial grants from the Department of Defense in USA and the German Research Council (DFG), amongst others.

  • Professional Background

    Education

    • 2016 - Postdoctoral Fellowship - Bone Repair and Regeneration - Inst. of Health & Biomedical Innovation - Queensland Univ. of Technology
    • 2012 - Postdoctoral Fellowship - Bone Repair and Regeneration - Julius Wolff Institute, Charité - Universitätsmedizin
    • 2010 - PhD - Medicine - University of Warwick
    • 2001 - MS - Biomechanical Engineering - Vilnius Gediminas Technical University
    • 1998 - BS - Biomechanical Engineering - Vilnius Gediminas Technical University

    Appointments

    • 1/2017 - Director of Basic Science Research - UT Health San AntonioSan Antonio
    • 8/2016 - Assistant Professor - UT Health San Antonio, Orthopaedics, San Antonio

  • Publications

      Journal Article

      Glatt V,Hohmann E, Tetsworth K. Swimming induced pulmonary oedema in athletes- a systematic review and best evidence synthesis BMC Sports Science, Medicine and Rehabilitation 2018 Nov;10(18). Glatt V, Corona PS, Vicente M, Tetsworth K. Preliminary results using patient-specific 3d printed models to improve preoperative planning for correction of post-traumatic tibial deformities with circular frames International Journal of the Care of the Injured 2018 Sep;49:51-59. Glatt V,Tetsworth K, Hohmann E. Minimally Invasive Plate Osteosynthesis of Humeral Shaft Fractures: Current State of Art Journal of the American Academy of the Orthopaedic Surgeons 2018 Sep;15(26):652-661. Glatt V, Hohmann E, Tetsworth K, Cote M. Arthroscopic Partial Meniscectomy versus Physical Therapy for degenerative Meniscus Lesions: How robust Is the Current Evidence? A Critical Systematic Review and Qualitative Synthesis NCBI 2018 Jul;. Glatt V, Hohmann E, Tetsworth K. Orthopaedic Academic Activity in the United States JAAOS Global Research 2018 Jul;2(7). Glatt V, Hohmann E, Myburgh J, Keough N, Tetsworth K. Inter-and intraclass correlations for three standard foot radiographic measurements for plantar surface angles. Which measure is most reliable? Foot and Ankle Surgery 2018 Jul;. Glatt V, Hohmann E, Tetsworth K. The hamstring/quadriceps ratio is an indicator of function in ACL-deficient, but not in ACL-reconstructed knees Archives of Orthopaedic and Trauma Surgery 2018 Jul;. Glatt V,Hohmann E, Keough N, tetsworth K, Putz R, Imhoff A. The mechanical properties of fresh versus fresh-frozen and preserved (Thiel and Formalin) long head of biceps tendons: a cadaveric investigation NCBI 2018 Jun;. Glatt V, Duryea J, Evans C. Image analysis software as a strategy to improve the radiographic determination of fracture healing Journal of Orthopaedic Trauma 2018 May;. Glatt V, Molepo M, Barnard AC, Birkholtz F, Tetsworth K, Hohmann E. Functional outcomes of the failed plate fixation in distal tibial fractures salvaged by hexapod external fixator European Journal of Orthopaedic Surgery and Traumatology 2018 May;. Glatt V, Muderis MA, Lu W, Tetsworth K. Two-Stage Osseointegrated Reconstruction of Post-traumatic Unilateral Transfemoral Amputees NCBI 2018 Mar;. Glatt V,Hohmann E, KONIG A, Kat CJ, Tetsworth K Keough N,. Single versus double-row repair for full-thickness rotator cuff tears using suture anchors. A systematic review and meta-analysis of basic biomechanical studies NCBI 2017 Dec;. Glatt V. Bone transport versus acute shortening for the management of infected tibial non-union NCBI 2017 Oct;. Glatt V, Tetsworth K, Paley D, Sen C, Jaffe M, Maar DC, Hohmann E, Herzenberg JE. bone transport versus acute shortening for the management of infected tibial non-unions with bone defects. Injury NCBI 2017 Jul;. Glatt V, Hohmann E, Tetsworth K. Early or delayed reconstruction in multi-ligament knee injuries: A systematic review and meta-analysis. Knee NCBI 2017 Jul;. Glatt V, Hohmann E, Tetsworth K. Open versus Arthroscopic surgical Treatment for Anterior Shoulder Dislocation: A Comparative Systematic review and Meta-Analysis Over the Past 20 Years NCBI 2017 Jul;. Glatt V,Hohmann E, Tetsworth K. Worldwide orthopaedic research activity 2010-2014: Publication rates in the top 15 orthopaedic journals related to population size and gross domestic product NCBI 2017 Jun;. Glatt V, Anthony J, Varughese I, Tetsworth K, Hohmann E. Influence of the Labrum on Version and Diameter of the Glenoid: A Morphometric Study Using Magnetic Resonance Images. Arthroscopy NCBI 2017 Apr;. Glatt V. Modulation of fixation stiffness from flexible to stiff in a rat model of bone healing Acta Orthopaedica 2017 Apr;. Glatt V. Response to letter to the editor regarding "Minimally invasive plating versus either open reduction and plate fixation or intramedullary nailing of humeral shaft fractures: a systematic review and meta-analysis of randomized controlled trials" Journal of Shoulder and Elbow Surgery 2017 Mar;. Glatt V, Hohmann E, Tetsworth K. Orthopaedic Research in Australia: A bibliographic analysis of the publication rates in the top 15 journals NCBI 2017 Mar;. Glatt V, Hohmann E, Birkholtz F, Tetsworth K,. The "Road to Union" protocol for the reconstruction of isolated complex high-energy tibial trauma.Injury NCBI 2017 Mar;. Glatt V,Tetsworth K, Block S. Putting 3D modelling and 3D printing into practice: virtual surgery and preoperative planning to reconstruct complex post-traumatic skeletal deformities and defects Sicot-J 2017 Feb;. Glatt V, Evans CH, Tetsworth K. Concert between Biology and Biomechanics: The Influence of the Mechanical Environment on Bone Healing Frontiers in Physiology 2017 Jan;. Glatt V, Tetsworth K, Fraser D, Hohmann E. Use of Google Scholar public profiles in orthopaedics NCBI 2017 Jan;. Glatt V, Green N, Tetsworth K, Wilson LJ, Grant CA. guide to Image Processing in the Creation of 3D Models for Orthopaedics Techniques in Orthopaedics 2016 Sep;. Glatt V, Grant CA, Izatt M, Labrom R, Askin G. Use of 3D Printing in Complex spinal Surgery: Historical Perspectives, Current usage and Future Directions Techniques in Orthopaedics 2016 Sep;. Glatt V,Hohmann e, Tetsworth K. MInimally Invasive Plating Versus Open Reduction and Plate Fixationand Intramedullary Nailing of Humeral shaft Fractures: a Systematic Review and Meta-Analysis of Randomized controlled Trials Journal of Shoulder and Elbow surgery 2016 Aug;. Glatt V, Tepic S, Evans CH. Reverse Dynamization: A Novel Approach to Bone Healing The Journal of American Academy of Orthopaedic Surgeons 2016 Jul;. Glatt V, wang X, Friis T, Crawford R, Xiao Y. Structural Properties of Fracture Hematoma: Current Status and Future Clinical Implications NCBI 2016 Jul;. Glatt V, Lui F, Porter RM, Wells J, Shen Z, Schinhan M, Ivkovic A, Vrahas MS, Evans CH, Ferreira E. Interaction between Living Bone Particles and rhBMP-2 in Large Segmental Defect Healing in the Femur Mayo Clinic 2016 Apr;. Glatt V,Bartinkowski N, Quirk N, Schuetz M, Evans CH. Reverse Dynamization: Influence of Fixator stiffness on the Mode and Efficiency of Large-Bone-Defect-Healing at Different Doses of rhBMP-2 The Journal of Bone and Joint surgery 2016 Apr;. Glatt V. The Osseointegration Group of Australia Accelerated Protocol (OGAAP-1) for Two-Stage Osseointegrated Reconstruction of Amputees The Journal of Bone and Joint Surgery 2016 Jan;. Glatt V,Hohmann E, Tetsworth K. Orthopaedic Research Activity in South Africa. Publication Rates in the 15 Highest Impact Journals related to Population Size and Gross Domestic Product SA orthop. j. [online] 2016 Jan;15:23-30. Glatt V,Lui F, Ferreira E, Porter RM, Schinhan, Shen Z, Randolph MA, Kirker-Head CA, Wehling C, Vrahas MS, Evans CH, Wells JW. Rapid and reliable healing of critical size bone defects with genetically modified sheep muscle NCBI 2015 Sep;.

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