Rachel Giese, MD

• Professional Background

  Education

  • 2010 - Doctor of Medicine (MD) - University of Texas Health Science Center, San Antonio, Texas
  • 2005 - Bachelor of Science in Chemistry - Georgia Institute of Technology, Atlanta, Georgia

• Instruction & Training

  • 2008 - 2009, Howard Hughes Medical Institute Research Fellowship,, NATIONAL INSTITUTES OF HEALTH, Bethesda, Maryland
  • 2010, Doctor of Medicine, University of Texas Health Science Center, San Antonio, Texas
  • 2010 - 2015, Residency in Otolaryngology ‑ Head and Neck Surgery, UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES, Little Rock, Arkansas
  • 2015 - 2016, Department Head/Neck Surgery Clinical Fellowship, MEMORIAL SLOAN KETTERING CANCER CENTER, New York, New York
  • 2016 - 2018, NIH NCI T32 Research Fellowship,, MEMORIAL SLOAN KETTERING CANCER CENTER, New York, New York

• Service

  School

  Academic Activities
  Director, MS3 & MS4 Otolaryngology and Plastic Surgery Clerkship (2019-2021)
  Member, Central Curriculum Committee Member (2019-2021)
  Chair, Clinical Integration Curriculum Subcommittee (2020)
  Trainer, Tracheostomy Care for Nursing & Respiratory Therapy
  Mentor, Medical Student Applicants in Surgical Specialties

  Community

  Community Outreach
  Mazumdar Shaw Cancer Center, Bangalore, India (April 2018)
  International Surgery Outreach, Uspantan, Guatemala (July 2008)
  International Medical Outreach, Comayagua, Honduras (March 2007)
  Rotary International Ambassador, University of Málaga, Málaga, Spain (2003/4)
  Medical Care for Patients Recovering from Substance Abuse, Alpha Home/SAMM Shelter, San Antonio, Texas
  Sharing Table, Meal Preparation for Homeless, New York, New York
  Aid the Silent, Hearing Aid Screening clinic, Edinburg, Texas

• Publications

  1. Gupta A, Budhu S, Fitzgerald K, Giese R, Michel AO, Holland A, Campesato LF, van Snick J, Uyttenhove C, Ritter G, Wolchok JD, Merghoub T. Isoform specific anti-TGFβ therapy enhances antitumor efficacy in mouse models of cancer. Commun Biol. 2021 Nov 17;4(1):1296. doi: 10.1038/s42003-021-02773-z. PMID: 34789823; PMCID: PMC8599839.
  2. Giese RA, Turner M, Cleves M, J. Gardner R, Richter G, Propranolol for Treatment of Infantile Hemangioma: Efficacy and Effect on Pediatric Growth and Development, International Journal of Pediatrics, vol. 2021, Article ID 6669383, 2021. https://doi.org/10.1155/2021/6669383 3. Budhu S, Giese R, Gupta A, Fitzgerald K, Zappasodi R, Schad S, Hirschhorn D, Campesato LF, De Henau O, Gigoux M, Liu C, Mazo G, Deng L, Barker CA, Wolchok JD, Merghoub T. Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma. Cell Rep. 2021 Jan 12;34(2):108620. doi: 10.1016/j.celrep.2020.108620. PMID: 33440157. 4. Wang, W., Dai, P., Yang, N., Giese, R.A., Shuman, S., Merghoub, T., Wolchok, J.D., and Deng, L. Elucidating Mechanisms of Antitumor Immunity Mediated by Live Oncolytic Vaccinia and Heat Innactivated Vaccinia. Submitted. 5. Ganly I, Yang L, Giese RA, Hao Y, Nossa CW, Morris LGT, Rosenthal M, Migliacci J, Kelly D, Tseng W, Hu J, Li H, Brown S, Pei Z. Periodontal pathogens are a risk factor of oral cavity squamous cell carcinoma, independent of tobacco and alcohol and human papillomavirus. Int J Cancer. 2019 Aug 1;145(3):775-784. doi: 10.1002/ijc.32152. Epub 2019 Feb 19. PMID: 30671943; PMCID: PMC6554043.
  6. Khalil DN, Suek N, Campesato LF, Budhu S, Redmond D, Samstein RM, Krishna C, Panageas KS, Capanu M, Houghton S, Hirschhorn D, Zappasodi R, Giese R, Gasmi B, Schneider M, Gupta A, Harding JJ, Moral JA, Balachandran VP, Wolchok JD, Merghoub T. In situ vaccination with defined factors overcomes T cell exhaustion in distant tumors. J Clin Invest. 2019 Jul 22;129(8):3435-3447.
  7. Moreno, Mauricio, Stack, Brendan C., editors. Neck Dissection. In: Radical Neck Dissection. Chapter 6. New York: Thieme; 2018.
  8. Shah, Jatin Editor, Oral Oncology. In: Premalignant Lesions of the Oral Cavity (Chapter 9). Maryland Heights: Mosby; 2017.
  9. Richter, Gresham, Suen, James, editors. Head and Neck Vascular Malformations: A Practical Case-Based Approach. In: Capillary Malformations Basic Tenants and Interventions (Chapter 3). San Diego: Plural Publishing; 2015.
  10. Richter, Gresham, Suen, James, editors. Head and Neck Vascular Malformations: A Practical Case-Based Approach. In: Lymphatic Malformations Basic Tenants and Interventions (Chapter 5). San Diego: Plural Publishing; 2015.
  11. Richter, Gresham, Suen, James, editors. Head and Neck Vascular Malformations: A Practical Case-Based Approach. In: Arteriovenous Malformations: Basic Tenants and Interventions (Chapter 6). San Diego: Plural Publishing; 2015.
  12. Kocdor P, Siegel ER, Giese R, Tulunay-Ugur OE. Characteristics of dysphagia in older patients evaluated at a tertiary center. Laryngoscope. 2015 Feb;125(2):400-5.
  13. Increased postoperative respiratory complications in heterotaxy congenital heart disease patients with respiratory ciliary dysfunction. Harden B, Tian X, Giese R, Nakhleh N, Kureshi S, Francis R, Hanumanthaiah S, Li Y, Swisher M, Kuehl K, Sami I, Olivier K, Jonas R, Lo CW, Leatherbury L. J Thorac Cardiovasc Surg. 2013 Jul 22.
  14. High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy. Nakhleh N, Francis R, Giese RA, Tian X, Li Y, Zariwala MA, Yagi H, Khalifa O, Kureshi S, Chatterjee B, Sabol SL, Swisher M, Connelly PS, Daniels MP, Srinivasan A, Kuehl K, Kravitz N, Burns K, Sami I, Omran H, Barmada M, Olivier K, Chawla KK, Leigh M, Jonas R, Knowles M, Leatherbury L, Lo CW. Circulation. 2012 May 8;125(18):2232-42.
  15. Bromophycolides C-I from the Fijian Red Alga Callophycus serratus. Kubanek, J., Prusak, A.C., Snell, T.W., Giese, R.A., Fairchild, C.R., Aalbersberg, W., and Hay, M.E. J. Nat. Prod., 69, 5, 731-735, 2006.
  16. Antineoplastic Diterpene-Benzoate Macrolides from the Fijian Red Alga Callophycus serratus. Kubanek, J., Prusak, A.C., Snell, T.W., Giese, R.A., Hardcastle, K.I., Fairchild, C.R., Aalbersberg, W., Raventos-Suarez, C., and Hay, M.E. Org. Lett., 7, 23, 5261-5264, 2005.

  Conferences and Presentations
  1. Phosphatidylserine targeting and Radiation Improves Survival in a mouse model of resistance to checkpoint blockade. American Association of Cancer Researchers (AACR), Chicago, IL. April 16, 2018.
  2. Predictive Factors for Occult Metastatic Disease in Patients Undergoing Salvage Laryngectomy with Elective Neck Dissection. International Federation of Head and Neck Oncologic Societies World Congress. July 2014.
  3. Propranolol for Treatment of Infantile Hemangioma: Efficacy and Effect on Pediatric Growth and Development. International Society for the Study of Vascular Anomalies (ISSVA) Meeting. Melbourne, Australia. April 2014.
  4. Response of 226 Port Wine Stain Patients to Laser Therapy. International Society for the Study of Vascular Anomalies (ISSVA) Meeting. Melbourne, Australia. April 2014.
  5. Genetic Testing in Patients with Vascular Malformations. International Society for the Study of Vascular Anomalies (ISSVA) Meeting. Melbourne, Australia. April 2014.
  6. Malignant Molecular Characteristics of Arteriovenous Malformations. Resident Research Day. Arkansas Children’s Hospital and University of Arkansas for Medical Sciences, Little Rock, AR. May 2013.
  7. Effect of Propranolol on Normal Pediatric Growth and Development During Hemangioma Therapy. Meeting of the American Society of Pediatric Otolaryngologists (ASPO). Crystal City, VA. April 2012.
  8. Patients with congenital heart disease and laterality defects exhibit ciliary dysfunction: Is this a possible contributor to surgical outcomes? Weinstein Cardiovascular Development Conference San Francisco, California. May 7-10, 2009.
  9. Muscle Regeneration and Inflammation in Aging Female MCP1 Mice. University of Texas Health Science Center at San Antonio Dean’s Medical Student Research Day. San Antonio, TX. 2006.

  Honors & Awards
  Sub-awardee of NIH R21: Mobile Detection of Oral Cancer (2021)
  University of Texas Rio Grande Valley Team Excellence Award (2021)
  New York Head and Neck Society Research Competition, 1st Place (2018)
  Resident Research Day Highest Excellence in Research (2015)
  Howard Hughes Medical Institute Research Fellowship (2008)
  Global Outreach Scholarship (2007)
  Dean’s Medical Student Research Day 2006, 1st Place Poster (2006)
  Georgia Tech IMPACT Scholarship, Campus Leader Recognition (2004)
  Rotary International Ambassador of Goodwill Scholarship (2003)
  Georgia Institute of Technology Presidents’ Scholarship (2000)
  William Donovan Memorial Scholarship (2000)