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Lily Dong

Contact

210-567-4849

dongq@uthscsa.edu

Departments & Divisions

Research

Research profile

Lily Q. Dong, Ph.D.

Professor

Department of Cell Systems and Anatomy

Currently seeking M.S. students

My laboratory studies fundamental mechanisms underlying insulin resistance and its related diseases including obesity and type 2 diabetes that have become the greatest threats to global human health. We have discovered and characterized several key molecules in adiponectin signaling and the roles in regulating the cross talk between adiponectin and insulin signal pathways. These mechanisms allow us to explore how insulin resistance initiates and develops, a major cause of metabolic disorders.  Throughout our work, we have developed a track record in molecular signaling, metabolism and disease studies.

  • Professional Background

    Education

    • 1995 - Postdoctoral Fellowship - Molecular Biology - Stanford University
    • 1991 - PhD - Biochemistry - Iowa State University
    • 1985 - MS - Biochemistry - Wuhan University
    • 1982 - BS - Biochemistry - Wuhan University

    Highlights

    Career Development Award (American Diabetes Association) (2005) 

    Award for Excellent in Graduate Student Education (Department of Cellular & Structural Biology, UTHSCSA) (2008)

    Named as an Academic Member (Master Teacher) by the UTHSCSA (2010)

    Named as Distinguished Teaching Professor by the University of Texas Board of Regents (2010)

    Presidential Teaching Excellent Award (UTHSCSA) (2013)

    Appointments

    • 9/2011 - Professor (With Tenure) - The University of Texas Health Science Center at San Antonio, Cellular & Structural Biology, San Antonio
    • 9/2007 - Associate Professor (With tenure)) - The University of Texas Health Science Center at San Antonio, Cellular & Structural Biology, San Antonio
    • 9/2002 - Assistant Professor (Tenure-track) - The University of Texas Health Science Center at San Antonio, Cellular & Strutural Biology, San Antonio
    • 09/1998 - Assistant Professor (Research) - Department of Pharmacology, UTHSCSA, San Antonio, Texas
    • 02/1996 - Instructor (Research) - Department of Pharmacology, University of Texas Health Science Center at San Antonio

  • Instruction & Training

    • 8/2017 - Present, Ph.D. Dissertations Directed, UTHSCSA
    • 6/2017 - Present, High School/Junior High School Student Supervision, UTHSCSA
    • 6/2017 - Present, High School/Junior High School Student Supervision, UTHSCSA
    • 1/2017 - Present, Ph.D. Dissertations Directed, UTHSCSA
    • 1/2017 - Present, Pre-Doctoral Student Supervision, UTHSCSA
    • 1/2017 - Present, Ph.D. Dissertations Directed, UTHSCSA
    • 8/2016 - Present, CSBL 5074 Introduction to Research
    • 5/2016 - Present, Ph.D. Dissertations Directed, UTHSCSA
    • 1/2016 - Present, Masters' Thesis Directed, UTHSCSA
    • 1/2016 - Present, Ph.D. Dissertations Directed, UTHSCSA
    • 8/2015 - Present, BIME 6004 Biology for Bioengineers
    • 8/2015 - Present, INTD 5000/Fundamentals of Biomedical Science/Obesity Team
    • 7/2015 - Present, Undergraduate Student Supervision, UTHSCSA
    • 6/2010 - Present, Undergraduate Student Supervision, UTHSCSA
    • 1/2009 - Present, Undergraduate Student Supervision, UTHSCSA
    • 2/2007 - Present, INTD5007 Advanced Cell and Molecular Biology

  • Research & Grants

    My laboratory studies fundamental mechanisms underlying insulin resistance and its related diseases including obesity and type 2 diabetes that have become the greatest threats to global human health. We have discovered and characterized several key molecules in adiponectin signaling and the roles in regulating the cross talk between adiponectin and insulin signal pathways. These mechanisms allow us to explore how insulin resistance initiates and develops, a major cause of metabolic disorders.  Throughout our work, we have developed a track record in molecular signaling, metabolism and disease studies.

    Research profile

    Grants

    Federal

    Funding Agency NIH/NIDDK, Title The role of TCTP in regulating adiponectin signaling, Period 04/2015 - 03/2021 (NCE), Role Principal Investigator , Grant Detail The major goals of this project are to determine the roles of NELF, a key Pol II-pausing factor, in regulating expression of genes involved in beige adipose thermogenesis.

    Funding Agency NIH/NIDDK, Title Regulation of Transcription Elongation in Adipose Homeostasis, Status Active Period 12/2017 - 11/2021, Role Principal Investigator, Grant Detail The major goals of this project are to determine the roles of NELF, a key Pol II-pausing factor, in regulating expression of genes involved in beige adipose thermogenesis. 

    Funding Agency NIH/NIDDK, Title Regulation of Mitochondrial Biogenesis and Function by DsbA-L in the liver, Status Active Period 04/2018 - 03/2022, Role Co-Investigator, Grant Detail The major goals of this project are to determine the role of Disulfide-bond-A oxidoreductase (DsbA)-like protein (DsbA-L) in regulating mitochondrial function in the liver.

    Private

     

    State

     

  • Publications