Yong-Hee P. Chun, D.D.S., Dr. med. dent., M.S., Ph.D.

Currently seeking M.S. & Ph.D. students

• Professional Background

  Education

  • 2009 - PhD - Oral Health Sciences - University of Michigan
  • 2003 - MS - Periodontics - University of Michigan
  • 2000 - Dr. med.dent. - Oral Biology - University of Goettingen, Germany
  • 1994 - DDS - Doctor of Dental Surgey - University of Goettingen, Germany

  Highlights

  2019 ADEA Leadership Institute, Fellowship

  2017 American Association for Dental Research Anne D. Haffajee Fellowship (inaugural)

  2015 Mu Nu Chapter of Omicron Kappa Upsilon (OKU)

  2014 Sunstar - American Academy of Periodontology Foundation Research Fellowship

  2003 American Academy of Periodontology, Chasens Fellowship for Teaching and Research

  Appointments

  • 1/2020 - Cross-appointed - UT Health San Antonio, Molecular Medicine
  • 9/2018 - Assocoiate Professor, tenured - UT Health San Antonio, Periodontics
  • 9/2017 - Associate Professor - UT Health San Antonio, Periodontics
  • 2/2014 - Cross-appointed - University of Texas Health Science Center at San Antonio, Cell Systems and Anatomy, San Antonio
  • 10/2013 - Assistant Professor and Tenure Track - University of Texas Health Science Center at San Antonio, Periodontics, San Antonio
  • 1/2010 - Assistant Professor/Research - University of Texas Health Science Center at San Antonio, Periodontics, San Antonio
  • 1995-2000 - Operative Dentistry, Preventive Dentistry & Endodontics - Charite University, Berlin, Germany

• Instruction & Training

  • 2021 - present, TSCI 5077, Practicum in Translational Science
  • 2014 - present, BIOC 5013 Biochemistry/ DHHD 5001 Human Health and Disease, UTHSA
  • 2011 - present, PERI 7081 Junior Periodontics, UTHSA
  • 2011 - present, PERI 5073/6073 Literature Seminars, UTHSA
  • 2011 - present, PERI 5047/6074 Current Lit Seminar, UTHSA
  • 2010 - present, PERI 5081/PERI 6082/ DIPC 5001/ DIPC 6002 Introduction to Patient Care, UTHSA
  • 2010 - present, MSDS 5020 Dental Biomedical Core Course, UTHSA
  • 2010 - present, PERI 5037 Bone & Connective Tissue Biology, UTHSA

• Research & Grants

  Dr. Chun's research areas are dental tissues, understanding pathways of diseases affecting them and developing precise dental therapies. The focus is the basement membrane protein ameloblastin. Ameloblastin is critical for enamel formation and belongs to the secreted calcium-binding phosphoproteins. As the hardest tissue of the body, enamel is a unique tissue and its formation by ameloblasts is accomplished by a transitioning through multiple stages. The duration of enamel formation from the initiation to final maturation is about 4 years. Diseases affecting enamel and surrounding structures include amelogenesis imperfecta, molar-incisor hypomineralization and periodontal disease.

  Grants

  • K08 - Role of ameloblastin for ameloblasts and enamel formation
  • R21 - Ameloblastin concentration on enamel formation
  • R01 - Enamel with overexpressed ameloblastin
  • R21 - Alternative splicing of ameloblastin in enamel formation
  • TL1 - NRSA Training Core

• Service

  Department

  • Faculty Promotion, Tenure and Appointment Committee (Chair)

  • Research Mentor

  School

  • Curriculum Committee – DS3 and 4 (Chair)

  • Curriculum Committee – DS1 and 2

  • Outcome Assessment Committee

  Institutional

  • Executive Committee of the Institute for Integration of Medicine & Science (IIMS)

  Service to the Profession

  • Southwest Society of Periodontists, Scientific Affairs Committee

  National

  • American Academy of Periodontology Foundation
  • NIH, NIDCR, Special Grants Review Committee
  • American Association for Dental Research, Committee on Diversity and Inclusion

• Publications

  Book Chapter

  • Harris SE, Rakian A, Foster BL, Chun YP, Rakian R. The Periodontium. Principles of Bone Biology, Academic Press, Cambridge, MA, 2019, 4th edition, p1061-1082
  • Chun YP, Krebsbach PH, Simmer JP. Craniofacial disorders affecting the dentition: Genetic. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 9th edition, 2018, American Society for Bone and Mineral Research Publications, Wiley-Blackwell
  • Chun YP, Hu JC-C. Clinical Correlates: dentinogenesis imperfecta, restorative procedures, caries. Mineralized Tissues in Oral and Craniofacial Science: Biological Principles and Clinical Correlates. IA, Section II: Teeth. Wiley-Blackwell, Ames, USA, 1st edition 2012, ISBN-13: 978-0470958339
  • Chun YP, Hu JC-C, Simmer JP. The non-amelogenins: Ameloblastin and Enamelin. Amelogenins: Multifaceted proteins for dental and bone formation & repair, Bentham Science Publishers, 1st edition, 2010, Chapter 5, 42-55

   

  Journal Article

  • Colley M, Liang S, Tan C, Trobough KP, Bach SBH, Chun YP. Mapping and identification of native proteins in mouse mandibles and tooth development. Anal Chem (2020) 92, 7630-7637
  • Hoskin E, Bertone M, Chun YP, Lee A, Motahari M, Martin A. Should dental school faculty be measured and compensated using academic productivity models? Two viewpoints. J Dent Edu (2020), 84, 534-542
  • Liang T, Hu Y, Smith CE, Richardson AS, Yang J, Lin B, Wang SK, Kim JW, Chun YP, Simmer JP, Hu J C-C AMBN mutations causing hypoplastic amelogenesis imperfecta and Ambn knockout-NLS-lacZ knockin mice exhibiting failed amelogenesis and Ambn tissue-specificity. Mol Genet Genomic Med, 2019, 7, e929
  • Klepper KL, Chun YP, Cochran D, Chen S, McGuff HS, Mealey BL. Impact of Er-YAG laser on wound healing following non-surgical therapy, A pilot study. Clin Exp Dent Res (2019) 5; 250-258
  • Pham CD, Smith CE, Hu Y, Hu J C-C, Simmer JP, Chun YP. Endocytosis and enamel formation Front Physiol (2017) 8, 529
  • Bizhang M, Schmidt I, Chun YP, Arnold WH, Zimmer S. Toothbrush abrasivity in a long-term simulation on human dentin depends on brushing mode and bristle arrangement. PLoS One (2017) 12, e0172060
  • Nunez SM, Chun YP, Ganss B, Hu Y, Richardson AS, Schmitz JE, Fajardo R, Yang J, Hu JC, Simmer JP Maturation stage enamel malformations in Amtn and Klk4 null mice. Matrix Biol (2016) 52-54, 219-233
  • Chan HL, Chun YP, MacEachern M, Oates TW. Does gingival recession require surgical treatment? Dent Clin North Am (2015), 59, 981-996
  • Guo F, Feng J, Wang F, Li W, Gao Q, Chen Z, Shoff L, Donly KJ, Gluhak-Heinrich J, Chun YP, Harris SE, MacDougall M, Chen S. Bmp2 deletion causes an amelogenesis imperfecta phenotype via regulating enamel gene expression. J Cell Physiol (2015) 230, 1871-1882
  • Rios HF, Bashutski JD, McAllister BS, Murakami S, Cobb CM, Chun YP, Lin Z, Mandelaris G, Cochran DL. Emerging regenerative approaches for periodontal reconstruction: Practical applications from the AAP Regeneration Workshop. Clin Adv Periodontics (2015) 5, 40-46
  • Cochran DL, Cobb CM, Bashutski JD, Chun, YP, Lin Z, Mandelaris G, McAllister BS, Murakami S, Rios HF. Emerging regenerative approaches for periodontal reconstruction: A consensus report. J Periodontol (2015) 86, 193-196
  • Teepe JD, Schmitz JE, Hu Y, Yamada Y, Fajardo RJ, Smith CE, Chun YP. Correlation of ameloblastin with enamel mineral content. Connect Tissue Res (2014) 55, 38-42
  • Schmitz JE, Teepe JD, Hu Y, Smith CE, Fajardo RF, Chun YP. Estimating mineral changes in enamel formation by ashing and MicroCT. J Dent Res (2014) 93, 256-262
  • Yeh C-K, Harris SE, Mohan S, Horn D, Fajardo R, Chun YP, Jorgensen J, MacDougall M., Abboud-Werner S. Hyperglycemia and xerostomia are key determinants of tooth decay in type 1 diabetic mice. Lab Invest (2012) 92, 868-882
  • Thoma DS, Villar CC, Carnes DL, Dard M, Ranevski R, Chun YP, Cochran DL. Angiogenic activity of enamel matrix derivative (EMD) and EMD-derived proteins: an experimental study in mice. J Clin Periodontol (2011) 38, 253-260
  • Chun YP, Lu Y, Hu Y, Krebsbach PH, Yamada Y, Hu JC-C, Simmer JP. Transgenic rescue of enamel phenotype in Ambn null mice. J Dent Res (2010) 89, 1407-1413
  • Chun YP, Yamakoshi Y, Yamakoshi F, Fukae M, Hu JC-C, Bartlett JD, Simmer JP. Cleavage site specificity of Mmp-20 for secretory stage ameloblastin. J Dent Res (2010) 89, 785-790
  • Chun YP, Raffelt C, Pfeiffer H, Blunck U, Saul G, Bizhang M, Roulet J-F. Restoring strength of incisors with veneers and full ceramic crowns. J Adhes Dent (2010) 12, 45-54
  • Yamashita J, Datta NS, Chun YP, Yang D-Y, Carey AA, Kreider JM, Goldstein SA, McCauley LK. Role of Bcl-2 in osteoclastogenesis, cell survival, and PTH anabolic actions in bone. J Bone Min Res (2008) 23, 621-632
  • Bizhang M, Chun YP, Heisrath D, Purucker P, Singh P, Kersten T, Zimmer S. Microbiota of exposed root surfaces after periodontal maintenance therapy. A 3-year evaluation. J Periodontol (2007) 78, 1580-1589
  • Hu JC-C, Chun YP, Al Hazzazzi T, Simmer JP. Enamel Formation and Amelogenesis Imperfecta. Cells Tissues Organ (2007) 186, 78-85

   

• Clinical

  Board Certifications

  • Diplomate of the American Board of Periodontology