Journal Article
22. Bi M, Zhang Z, Jiang Y, Xue P, Wang H, Lai Z, Fu X, De Angelis C, Gong Y, Gao Z, Ran J, Jin V, Marangoni E, Montaudon E, Galss C, Li W, Huang T, Shao Z, Schiff R, Chen L* and Liu Z*. “Enhancer Reprogramming Driven by High-order Assemblies of Transcription Factors Promotes Phenotypic Plasticity to Achieve Breast Cancer Endocrine Resistance” Nature Cell Biology. 2020 https://doi.org/10.1038/s41556-020-0514-z
21. Zhang Z, Yu W, Tang D, Zhou Y, Wang H, Bi M, Zheng Y, Xu X, Zhang W, Tao H, Jin V, Liu Z* and Chen L*. (2020) Epigenomics-Based Identification of Estrogen-regulated Long Noncoding RNAs in ER+ Breast Cancer. RNA Biology. In Press
20. Ko SH, Apple EC, Liu Z*, Chen L*. Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH. Autophagy. 2020 Jan 13;:1-17. doi: 10.1080/15548627.2020.1713645. PMID: 31920157. * co-corresponding authors
19. Chen L, Liu Z. Multifaceted function of YAP/TEAD on chromatin:prospects of 'A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer'. J Mol Cell Biol. 2019 Dec 19;11(12):1101-1103. doi: 10.1093/jmcb/mjz106. PMID: 31774121
18. Apple E and Chen L (2019). Neuronal microtubules impact lifespan. Aging (Albany NY). 2019 Sep 6;11(17):6616-6617. doi: 10.18632/aging.102224.
17. Zhu C, Li L, Zhang Z, Bi M, Wang H, Su W, Hernandez K, Liu P, Chen J, Chen M, Huang TH, Chen L* and Liu Z*. A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer. Molecular Cell, 2019 PMID: 31303470 * co-corresponding authors
16. Wang H, Webster P, Chen L and Fisher AL (2019). Cell-autonomous and non-autonomous roles of daf-16 in muscle function and mitochondrial capacity in aging C. elegans. Aging (Albany NY). 2019 Apr 30; 11(8): 2295-2311. Doi: 10.18632/aging.101914. PMID: 31017874
15. Xu A, Zhang Z, Ko S, Fisher L, Liu Z and Chen L (2019). Microtubule regulators regulate neuronal aging and organismal longevity through DAF-16 in C. elegans. Aging Cell. 2019 Apr;18(2):e12884. doi: 10.1111/acel.12884. PMID: 30638295
14. Chen L. Microtubules and axon regeneration in C. elegans. Mol Cell Neurosci. 2018 Sep;91:160-166. doi: 10.1016/j.mcn.2018.03.007. Epub 2018 Mar 16 PMID: 29551667
13. Chen L, Liu Z, Zhou B, Wei C, Zhou Y, Rosenfeld M, Fu X, Chisholm A and Jin Y (2016) CELF RNA binding proteins promote axon regeneration in C. elegans and mammals through alternative splicing of syntaxins. eLife.16072. PMID: 27253061
12. Chen L, Chuang M, Koorman T, Boxem M, Chisholm A and Jin Y (2015) Axon injury triggers EFA-6 mediated destabilization of axonal microtubules via TACC and doublecortin like kinase. eLife.08695. PMID: 26339988
11. Grill B, Chen L, Bienvenut W, Anderson M, Quadroni M, Jin Y and Garner CC (2012) RAE-1 a novel PHR binding protein is required for axon termination in C. elegans. Journal of Neuroscience 32(8):2628-36 PMID: 22357847
10. Chen L, Wang Z, Hubert T, Ghosh-Roy A, O’ Rourke S, Bowerman B, Wu Z, Jin Y, Chisholm A. (2011) Axon regeneration pathways identified by systematic genetic screening in C. elegans. Neuron 71(6):1043-57 PMID: 21943602
9. Chen L and Chisholm A. (2011) Axon regeneration mechanisms: insights from C.elegans. Trends in Cell Biology 21(10):577-84 PMID: 21907582
8. Chen L, Zhao P, Wells L, Amemiya C, Condie B, Manley N. (2010) Mouse and zebrafish Hoxa3 orthologs have non-equivalent in vivo protein function. PNAS vol. 107 no. 23 10555-10560 PMID: 20498049
7. Liu Z, Farley A, Chen L, Kirby BJ, Kovacs CS, Blackburn C, Manley N. (2010) Thymus-associated parathyroid hormone has two cellular origins with distinct endocrine and immunological functions. PLoS Genetics 6(12): e1001251 PMID: 21203493
6. Chen L, Xiao S, Manley N. (2009) Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner. Blood. 113(3):567-74 PMID: 18978204
5. Wang ZR, Guo L, Chen L, McEachern MJ. (2009) Evidence for an additional base-pairing element between the telomeric repeat and the telomerase RNA template in Kluyveromyces lactis and other yeasts. Mol Cell Bio. 29(20):5389-98 PMID: 19687297
4. Liu X, Chen Y, Zhang F, Chen L, Ha T, Gao X, Li C. (2007) Synergistically therapeutic effects of VEGF165 and angiopoietin-1 on ischemic rat myocardium. Scand Cardiovasc J. 41(2):95-101 PMID: 17454834
3. Zhang F, Yang Z, Chen Y, Qin J, Zhu T, Xu D, Xu Z, Xu Q, Qian Y, Ma W, Chen L, Gao X, Li C, Ha T, Kao RL. (2003) Clinical cellular cardiomyoplasty: technical considerations. J Card Surg. 18(3):268-73 PMID: 12809404
2. Chen L, Gao X. Neuronal apoptosis induced by endoplasmic reticulum stress. (2002) Neurochem Res. 27(9):891-8 PMID: 12396099
1. Jiang P, Chen L, Lin J, Liu Q, Ding J, Gao X, Guo Z. (2002) Novel zinc fluorescent probe bearing dansyl and aminoquinoline groups. Chem Commun (Camb). (13):1424-5 PMID: 12125585