Muhammad Abdul-Ghani, MD, PhD
Professor/Research
Muhammad Abdul-Ghani, MD, PhD is a Professor of Medicine at the Diabetes Division, University of Texas Health Science Center at San Antonio. He graduated from the MD, PhD program of the Hebrew University of Jerusalem. His research interest focuses on the pathophysiology, prevention and treatment of type 2 diabetes. He has published over 160 articles in peer reviewed journal in the field and has been consecutively funded by the NIH/NIDDK for over 15 years. He has made major innovative discoveries about the pathophysiology and treatment of IGT/IFG and type 2 diabetes. His cleric EPIC and QATAR studies has led the American Diabetes Association to recommend for the first time, initiation of therapy in newly diagnosed T2DM patients with combination therapy. He has made many terminal observations about the mechanism of costa of the SGLT2 inhibitors, GLP-1 receptor agonists, and thiazolidinediones.
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Publications
- Triplitt C, Solis-Herrera C, Cersosimo E,Abdul-Ghani M, Defronzo RA. Empagliflozin and linagliptin combination therapy for treatment of patients with type 2 diabetes mellitus. Expert Opin Pharmacother. 2015 [Epub ahead of print]
- Abdul-Ghani M, DeFronzo RA. The place of renal sodium-glucose co-transport in the management of type 2 diabetes mellitus. Am J Physiol. 2015 (ahead of print).
- Kanat M, DeFronzo RA and Abdul-Ghani M, Treatment of prediabetes. World J Diabetes. 6:1207-22, 2015
- Abdul-Ghani MA, Puckett C, Triplitt C, Maggs D, Adams J, Cersosimo E, DeFronzo RA Initial Combination Therapy with Metformin/Pioglitazone/Exenatide is More Effective Than Sequential Add-On Therapy in Subjects with New Onset Diabetes. Results from the Efficacy and Durability of Initial Combination Therapy for Type 2 Diabetes (EDICT): A Randomized Trial. Diabetes Obes Metab. 17:268-75, 2015
- Winnier DA, Fourcaudot M, Norton L, Abdul-Ghani MA, Hu SL, Farook VS, Coletta DK, Kumar S, Puppala S, Chittoor G, Dyer TD, Arya R, Carless M, Lehman DM, Curran JE, Cromack DT, Tripathy D, Blangero J, Duggirala R, Göring HH, DeFronzo RA, Jenkinson CP. Transcriptomic Identification of ADH1B as a Novel Candidate Gene for Obesity and Insulin Resistance in Human Adipose Tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES).PLoS One. 10:e0119941, 2015
- Valaparla SK; Gao F; Daniele G; Abdul-Ghani M; Clarke GD. Fiber orientation measurements by diffusion tensor imaging improve hydrogen-1 magnetic resonance spectroscopy of intramyocellular lipids in human leg muscles Journal of Medical Imaging 2: 026002, 2015