Jing Yong Ye, Ph.D.
Professor of Biomedical Engineering
UTSA
Currently seeking M.S. & Ph.D. students
Biophotonics, Bioimaging, Biosensing, Cancer diagnosis, Drug delivery, Neuroengineering Research
Dr. Jing Yong Ye’s research is focused on biophotonics and nanobiotechnology. He has developed a number of innovative technologies for biomedical imaging and sensing applications and holds 14 patents. He has invented and developed a unique label-free biosensor by utilizing photonic crystal structures in a total-internal-reflection configuration, which has been demonstrated for a wide range of applications. For instance, the biosensor is highly sensitive in the detection of cardiac biomarkers for potential rapid diagnosis of myocardial infarction. Dr. Ye has also been working with his collaborators with a major grant from USDA to screen different peptides for the treatment of a serious soybean plant disease. Moreover, he has developed an innovative approach for sensitive detection of endotoxin that has great potential to be utilized by pharmaceutical industry for quality control of parenteral pharmaceuticals and implantable medical devices. His new approach has improved the assay sensitivity of endotoxin by 200 times compared to the best commercially available systems and reduced the time needed for the assay by more than half. Recently, supported by two NIH grants, Dr. Ye and his collaborators have been working on developing new techniques for prostate cancer detection as well as for drug screening of cardiotoxicity by utilizing a label-free biosensor in conjunction with a heart-on-a-chip. In addition, Dr. Ye has been working on photoacoustic tomography for cancer diagnosis and brain imaging, fluorescence biosensing/imaging based on a patented double-clad fiber, as well as nanoparticle-based drug delivery system for enhanced treatment of cancer.
Associated Diseases: Breast Cancer, Prostate Cancer, Neurodegenerative diseases
Techniques Used: Label-free biosensing, Photoacoustic imaging, Fiber-based fluorescence biosensing