Skip to main content

Part of UT Health San Antonio

Profiles - UT Health San AntonioProfiles - UT Health Science Center San Antonio

Part of UT Health San Antonio

Menu
  • Home

You are here

  • Profiles Home
  • Faculty Directory
  • Xiaodu Wang
Xiaodu Wang

Contact

210-458-5565

xiaodu.wang@utsa.edu

Programs

  • M.S. in Biomedical Engineering
  • Ph.D. in Biomedical Engineering

Currently seeking M.S. students

Xiaodu Wang, Ph.D.

Professor

ASME and AIMBE Fellow

Department of Mechanical Engineering, UTSA

My research interests lie in the area of mechanics of biological materials and structures, including ultrastructural origins of bone fragility fractures, digital model of trabecular bone and its application in deep learning prediction of bone fractures, and prediction/prevention of bone fragility fractures. I have been serving as PI for multiple NIH (R03, R21s and R01s) and NSF supported projects.

Related Diseases: Osteoporosis, osteopenia, osteogenesis imperfecta and diabetes

Techniques: MicroCT, synchrotron X-ray scattering, light and confocal microscopy, FTIR, Raman spectroscopy, SEM, TEM, AFM, NMR/MRI, DXA, HPLC and Mechanical testing

  • Research & Grants

    My research interests lie in the area of mechanics of biological materials and structures, including ultrastructural origins of bone fragility fractures, digital model of trabecular bone and its application in deep learning prediction of bone fractures, and prediction/prevention of bone fragility fractures. I have been serving as PI for multiple NIH (R03, R21s, and R01s) and NSF supported projects.Diseases Associated: Osteoporosis, osteopenia, osteogenesis imperfecta, diabetes.
    Techniques Used: MicroCT, synchrotron X-ray scattering, Light and confocal microscopy, FTIR, Raman spectroscopy. SEM, TEM, AFM, NMR/MRI, DXA, HPLC, Mechanical testing

  • Publications

      Xiaodu Wang, Haoran Xu, Yehong Huang, Sumin Gu, and Jean Jiang: Coupling effect of water and proteoglycan on the in situ toughness of bone, JBMR, (2016) 31(5): 1026-1029.

      Liqiang Lin, Jitin Samuel, Xiaodu Wang, and Xiaowei Zeng: Contribution of extrafibrillar matrix to the mechanical behavior of bone using a novel cohesive finite element model, Journal of Mechanical Behavior of Biomedical Materials, (2016) 65: 224-235.

      Xiao Yang, Ahmed Jenan Mostafa, Mark Appleford, Lian-Wen Sun, and Xiaodu Wang: Bone formation is affected by matrix advanced glycation end products (AGEs) in vivo, Calcified Tissue International, (2016) 99(4): 373-383

      X. Dong, H. Leng, Q. Ran, X. Wang: Finding of microdamage morphology differences in mice femoral bones with distinct mineralization levels, Journal of Mechanics in Medicine and Biology (2010) accepted.

      Silva, M. J., Brodt, M. D., Lynch, M. A., McKenzie, J. A., Tanouye, K. M., Nyman, J. S., Wang, X: Type 1 diabetes in young rats leads to progressive trabecular bone loss, cessation of cortical bone growth, and diminished whole bone strength and fatigue life, Journal of bone and mineral research, 24 (2009) 1618-27

      X. Dong, T. Guda, H.R. Millwater, X. Wang: Probabilistic prediction of microdamage progression in bone using a finite element model of mineral-collagen composites, J. Biomech. 42 (2009) 202-209.

      Y. Yang, S. Park, Y. Liu, K. Lee, H. Kim, J. Koh, X. Meng, K. Kim, H. Ji, X. Wang, J. Ong: Development of sputtered nanoscale titanium oxide coating on osseointegrated implant devices and their biological evaluation, Vacuum 83 (2009) 569-574.

      H. Leng, X. Dong, and X. Wang: Progressive post-yield behavior of human cortical bone in compression for middle-aged and elderly groups, J. Biomech. 42 (2009) 491-497

      J.S. Nyman, H. Leng, X. Dong, X. Wang: Differences in the mechanical behavior of cortical bone between compression and tension when subjected to progressive loading, Journal of Mechanical Behavior of Biomaterials, 2 (2009) 613-619

      J.S. Nyman; Q. Ni, D.P. Nicollela, X. Wang: Measurements of mobile and bound water by nuclear magnetic resonance correlate with mechanical properties of bone, Bone 42 (2008) 193–199.

      X. Wang, J.S. Nyman: A novel approach to assess post-yield energy dissipation of bone in tension, J. Biomech. 40 (2007) 674-7.

      X. Wang, Y.J. Yoon, & H. Ji: A novel scratching approach for measuring age-related changes in the in situ toughness of bone, J. Biomech. 40 (2007) 1401-4.

      S. Parachuru, A Jain, and X. Wang: Size requirements of compact sandwich specimen for testing of bone, J. Mechanics in Medicine and Biology 7 (2007) 419-431

      J.S. Hyman, A. Roy, J.H. Tyler, R. Acuna, H.J. Gayle, and X. Wang: Age-related factors affecting the post-yield energy dissipation of human cortical bone. J. Orhtop. Res. 25 (2007) 646-655.

      Q. Ni, J. S. Nyman, X. Wang, A. De Los Santos, and D.P. Nicolella: Assessment of water distribution changes in human cortical bone by nuclear magnetic resonance,Meas. Sci. Technol. 18 (2007) 1–9.

      J.S. Nyman, A. Roy, R.L. Acuna, H.J. Gayle, M.J. R eyes, J.H. Tyler, D.D. Dean, and X. Wang: Age-related effect on the concentration of collagen crosslinks in human osteonal and interstitial bone tissue, Bone, 39 (2006) 1210-1217.

      J.G. Fleischli, T.J. Laughlin, K.A. Athanasiou, D.R. Lanctot, L. Lavery, X. Wang, and C.M. Mauli: Effect of diabetes mellitus on the material properties of the distal tibia. Journal of the American Podiatric Association, (2006) 96(2) 91-95.

      J. Nyman, A. Roy, X. Shen, and X. Wang: The influence of water distribution on the strength and toughness of cortical bone, J. Biomech. (2006) 39(5) 931–938.

map image

UT Health San Antonio

7703 Floyd Curl Drive
San Antonio, TX 78229

210-567-7000

We make lives better ©

We're a part of UT Health San Antonio, provider of comprehensive health,  dental, &  cancer care,  advanced academics,  and  life-saving research.

Web Privacy | Links from websites affiliated with The University of Texas Health Science Center at San Antonio's website (uthscsa.edu) to other websites do not constitute or imply university endorsement of those sites, their content, or products and services associated with those sites. The content on this website is intended to be used for informational purposes only. Health information on this site is not meant to be used to diagnose or treat conditions. Consult a health care provider if you are in need of treatment.