Robert Davey, Ph.D.
Texas Biomedical Research Institute/ Boston University
Dr. Robert Davey joined the Texas Biomedical Research Institute in 2011, coming from the University of Texas Medical Branch, Galveston. Before that, he was at Harvard Medical School in Boston, where he was an instructor in medicine. Currently, Dr. Davey is the Ewing Halsell Scholar and Scientist at Texas Biomedical Research Institute department of Virology and Immunology. His recent work has been focused on identification of cellular factors important for establishing infection by filovirus and bunyaviruses. His work has culminated in a deeper understanding of the entry and cell signaling pathways that are used by these viruses to penetrate the cell membrane and establish infection. His recent work with Ebolavirus has been published in the high-impact journals PLoS Pathogens, PNAS and a new article on host factor dependence in Science that was featured on the cover page. Dr. Davey’s group works collaboratively with a number of groups providing sophisticated molecular biology and cell biology techniques for the study of pathogenic viruses including Ebolavirus for which the lab mainly works. He has developed high throughput screening techniques for Ebolavirus. He also performs contract work testing drugs and compounds for ebolavirus infection inhibition. His team is well trained in ABSL4 procedures and have been working with Ebolavirus since 2006.
GRB2 interaction with the ecotropic murine leukemia virus receptor, mCAT-1, controls virus entry and is stimulated by virus binding
Chen Z, Kolokoltsov AA, Wang J, Adhikary S, Lorinczi M, Elferink L, Davey RA
J Virol 86: 1421-32, 2012
PubMed ID: 22090132
Inhibition of Lassa virus and Ebola virus infection in host cells treated with the kinase inhibitors genistein and tyrphostin
Kolokoltsov AA, Adhikary S, Garver J, Johnson L, Davey RA, Vela EM
Arch Virol 157: 121-7, 2012
PubMed ID: 21947546