Eric Brey, Ph.D.
Chair of the Department of Biomedical Engineering
My laboratory is focused on the fields of tissue engineering, regenerative medicine and biomaterials. Specifically, we are investigating new biomaterial approaches for engineering vascularized tissues. We are also investigating novel imaging methods for analysis and monitoring of engineered tissues. Our research has received support from the National Science Foundation, the National Institutes of Health, the Department of Defense, the Veterans Administration and industry collaborators. In addition to research, I have a significant interest in engineering education, specifically in the area of undergraduate research and its influence on education and career trajectories.
Jiang B., Akar B, Waller TM, Larson JC, Appel AA, Brey E.M. Design of a biocomposite
biomaterial system for tissue engineering applications. Acta Biomaterialia. 10(3):1177-86, 2014.
Vaicik M.K., Kortesmaa J.T., Movérare-Skrtic S., Kortesmaa J., Soininen R., Bergström G., Ohlsson C., Chong L.Y., Rozell B., Emont M., Cohen R.N., *Brey E.M., *Tryggvason K. * Equal contribution as senior author. laminin α4 deficient mice exhibit decreased capacity for adipose tissue expansion and weight gain. PLoS One. 9(10):e109854, 2014.
Appel A.A., Larson J.C., Garson III A.B., Guan H, Zhong Z., Nguyen B.N., Fisher J.P. Anastasio M.A., Brey E.M. X-ray phase contrast imaging of calcified tissue and biomaterial structure in bioreactor engineered tissues. Biotechnology and Bioengineering. 112(3):612, 2015.
Wang M.O., Vorwald C.E., Dreher M.L., Mott E.J., Cheng M.H., Cinar A., Mehdizadeh H., Somo S., Dean S., Brey E.M., Fisher J.P. Evaluating 3D Printed Biomaterials as Scaffolds for Vascularized Bone Tissue Engineering. Advanced Materials. 27(1):138, 2015.
Somo S., Akar B., Bayrak E.S., Larson J.C., Appel A.A., Mehdizadeh H., Cinar A., Brey E.M. Vascularized Tissue Formation in Biomaterials is Controlled by Pore Interconnectivity. Tissue Engineering Part A. Accepted.
Roux B.M., Cheng M.H., Brey E.M. Engineering Clinically-Relevant Volumes of
Vascularized Bone. Journal of Cellular and Molecular Medicine. 19(5):903, 2015.
Vaicik M.K., Morse M., Blagajcevic A., Rios J., Larson J., Yang F., Cohen R.N., Papavasiliou G., Brey E.M. Hydrogel-Based Engineering of Beige Adipose Tissue. Journal of Materials Chemistry B: Materials for biology and medicine. Accepted.